Investigate applicability on single cell datasets

[nictru]

Credits to Katie Hoadley, who would be interested in using this on a dataset of hers

[mlist]

Fatemeh has already done work in this direction, e.g. https://pubmed.ncbi.nlm.nih.gov/33124660/ but generally a good idea to adapt our pipeline to sc data now that Nico knows that format as well ;-)

[nictru]

Some meeting notes:

• Maybe @quirinmanz has some fitting datasets
• Look into Fatemehs paper and potentially use this instead of DYNAMITE
• We should investigate sample aggregation (peak mixing), if the current implementation makes sense in this context

[quirinmanz]

Not sure what exactly you need/are looking for?
scATAQ-seq? I don't have one lying around, at the moment

[nictru]

We would require RNA-Seq and any kind of HM-ChIP-Seq, ATAC-Seq or DNAse-Seq data. Is not on top of our priority, if someone stumbles across such a dataset, leave a note here

[quirinmanz]

https://www.nature.com/articles/s41576-022-00509-1/tables/2
There will be more datasets available soon I think

[mlist]

how about this: https://support.10xgenomics.com/single-cell-multiome-atac-gex/datasets/1.0.0/pbmc_granulocyte_sorted_10k