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Seabreeze: an automated pipeline for structrual variant analysis of bacterial resequencing experiments

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seabreeze

workflow seabreeze is a tool for the comprehensive analysis of structural variant (SVs) mutations in bacterial resequencing experiments. seabreeze automates and unites several analyses into a single, easy-to-use pipeline. For specified pairs of bacterial genomes, it can:

  • Compute size difference between genomes
  • Predict the location of insertion sequences
  • Predict SVs (inversions, deletions, translocations, duplications)
  • Generate intuitive synteny plots to visualise SVs
  • Analyse the effect of SVs on the balance of the two replichores
  • Predict the putative mechanism of inversions and deletions
  • Annotate the genes contained in the mutated regions

Please refer to the official documentation for information on installation and usage.

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Seabreeze: an automated pipeline for structrual variant analysis of bacterial resequencing experiments

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