Enrichment analyses

Usage

Two tools are available to perform enrichment analyses on your dataset: Gprofiler and GSEA.

To use them, simply click on the respectives buttons after loading your dataset.

• Gprofiler launch a query to several pathways databases with the current selection of gene. It generate a plot and a pable, accessible with two tabs. You can also select the organism on which you would like to submit the query (for now only Human and Dog are implemented in the application). Unlike the Volcano plot, you should click the button if you want to launch gprofiler again.

• GSEA launch a query to one specified pathway database, which you can select next to the button. Unlike the volcano plot or the Gprofiler analysis, it always launch on the complete list of genes, and it takes into account the Log2FoldChange of every gene into the analysis. Three tabs are available for this analysis: one barplot with over- and under- expressed pathways, one with a network representation of these pathways and genes associated (this can lag if too many nodes), and one with a table.