Release Notes (CurveAlign)

Release Notes of CurveAlign

CurveAlign v5.0 Beta major updates (March, 2020):

1. Add an HSV color based registration and segmentation for automatic boundary creation
2. Add alignment measurement between individual fiber features in addition to relative angle with respect to tumor boundary
3. Add density/intensity estimation module for user defined individual ROIs
4. Add synthetic fiber generator module to create synthetic fibers with user specified fiber properties
5. Add fast individual fiber estimation using C++ mex functions in CT-FIRE
6. Provide headless functions to run on distributed computer system such as CHTC (The Center for High Throughput Computing, UW-Madison)

CurveAlign v4.0 Beta major updates (August, 2017):

1. Add an automatic boundary creation module to automatically register H&E image with SHG image, and then segment boundaries based on the registered H&E bright field image
2. Add the ROI manager for defining the regions of interest in an image
3. Add ROI analysis for post-processing CurveAlign analysis results of an individual image
4. Add ROI analysis for running CurveAlign on the defined ROIs of individual image for orientation and alignment measurement with Curvelets
5. Add ROI analysis and ROI post-processing for the defined ROIs in multiple images
6. Add output table to selectively display the alignment information as well as the associated overlay, heatmap and histogram figures
7. Add options in Curveletsbased analysis to allow the user to specify the scale to be used and the radius to group the curvelets
8. Add an option to select/un-select the fibers within a tiff boundary
9. Add options to control the heat map of the relative angle or localized alignment;
10. Add a function to manually draw tiff boundaries
11. Fix a bug in the measurement and output of the relative angle
12. Add the function to combine the results in a selected folder of CurveAlign output.

CurveAlign version 3.0 major updates (December 2014):

Compared to the version 2.3, its primary change is adding fiber feature extraction from CT-FIRE output

1. Output up to thirty four fiber features, including angle, alignment, density, and etc. , these features are saved in both .csv file and .mat file
2. Multiple tiff boundaries can be loaded to investigate the interaction between fiber and cell
3. Read in CT-FIRE fiber extraction results
4. A feature ranking using linear support vector machine approach is included
5. Keep the most features of the older version (2.3), such as the statistics for the relative angles, heat map to show the fiber (angle) alignment, and the fiber-boundary association, etc.