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Building 3D Digital Mouse Lemur Brain Atlas

Manual annotation of the brain regions on brain slice images is a highly time-consuming and demanding job. By training with only one annotated dataset, we obtain the deep neural networks that can be used for annotating other datasets of same-species animals. Our deep neural networks enable us to automatically annotate datasets with a significantly reduced amount of time. In addition, we create a digital brain atlas with 3D meshes by registering the annotated dataset to the blackface image.


Hierarchically Organized Brain Regions

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Big Region Annotation

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Subregion Annotation

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Construction of a Reference Template

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Results

  • Deep Neural Network and Algorithm for Automatic Brain Region Annotation
  • 3D Digital Brain Atlas

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atlas_3d


Detailed Pipeline for Building 3D Digital Brain Atlas

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Principal Investigator of The Project : Linqing Feng(Ph.D), Korea Institute of Science and Technology