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Made updates pertaining to PIP-ECHO #2468

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The current version of mzLib has had some significant changes made to MBR in FlashLFQ.

This update supports those changes.

  • Added property to SearchParameters - MbrFdrThreshold. This controls the FDR of MBR identifications

    • Added text box in Search Task to allow users to set this parameter
  • Call to the FlashLFQ engine in PostSearchAnalysisTask receives additional argument - PeptidesToQuantify

    • This ensures that only peptides with a peptide-level Q-value <0.01 are written to the output and used to calculate protein intensities
  • Identifications passed in to FlashLFQ now have additional information: Score, Q-value, and bool isDecoy.

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codecov bot commented Feb 8, 2025

Codecov Report

Attention: Patch coverage is 96.29630% with 1 line in your changes missing coverage. Please review.

Project coverage is 93.95%. Comparing base (9c9fe5a) to head (273b1a6).

Files with missing lines Patch % Lines
...eus/TaskLayer/SearchTask/PostSearchAnalysisTask.cs 95.83% 0 Missing and 1 partial ⚠️
Additional details and impacted files

Impacted file tree graph

@@            Coverage Diff             @@
##           master    #2468      +/-   ##
==========================================
+ Coverage   93.93%   93.95%   +0.01%     
==========================================
  Files         149      149              
  Lines       22474    22496      +22     
  Branches     3090     3092       +2     
==========================================
+ Hits        21111    21135      +24     
+ Misses        911      908       -3     
- Partials      452      453       +1     
Files with missing lines Coverage Δ
MetaMorpheus/EngineLayer/SpectralMatch.cs 97.85% <100.00%> (ø)
...aMorpheus/TaskLayer/SearchTask/SearchParameters.cs 100.00% <100.00%> (ø)
...eus/TaskLayer/SearchTask/PostSearchAnalysisTask.cs 94.15% <95.83%> (+0.27%) ⬆️

... and 1 file with indirect coverage changes

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