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added oncotools link
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sigven committed Oct 27, 2021
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**oncoEnrichR** is an R package for functional interrogation of human genesets in the context of cancer. The package leverages an extensive amount of prior molecular knowledge for geneset interpretation along multiple dimensions.

Web-based access to **oncoEnrichR** is available at <https://oncotools.elixir.no>

**oncoEnrichR** is primarily intended for exploratory analysis and prioritization of a gene list (referred to here as **query set**) from high-throughput cancer biology experiments, e.g. genetic screens (siRNA/CRISPR), protein proximity labeling, or transcriptomics (differential expression). The tool queries a number of high-quality data resources in order to assemble useful gene annotations and analyses in an interactive report (examples from the report shown below).

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- October 27th 2021: **1.0.6 release**

- Addition of new modules

- Regulatory interactions - DoRothEA
- Ligand-receptor interactions - CellChatDB

- Data updates: Open Targets Platform, KEGG, WikiPathways, CancerMine, TCGA, EFO, DiseaseOntology

- Additional dedicated enrichment plots (GO)

- Improved target rankings (tissue- and celltype enrichment, regulatory interactions)

- See complete [CHANGELOG](https://sigven.github.io/oncoEnrichR/news/index.html)

- July 8th 2021: **1.0.4 release**
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- [NetPath](http://www.netpath.org) - signaling transduction pathways
- [STRING](https://string-db.org) - protein-protein interaction database
- [CORUM](https://mips.helmholtz-muenchen.de/corum/) - protein complex database
- [Compleat](https://fgr.hms.harvard.edu/compleat>) - protein complex resource
- [Compleat](https://fgr.hms.harvard.edu/compleat%3E) - protein complex resource
- [ComplexPortal](https://www.ebi.ac.uk/complexportal/home) - manually curated, encyclopaedic resource of macromolecular complexes
- [hu.MAP2](http://humap2.proteincomplexes.org) - human protein complex map
- [ComPPI](http://comppi.linkgroup.hu/) - subcellular compartment database
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