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Candida glabrata response to stress

Candida glabrata is the human-pathogenic fungi causing dreadful infections in immuno-compromised individuals. It can tolerate high levels of oxidative stress (OS) and proliferate inside phagocytes. Earlier studies have shown how it responds upon encounter to oxidative stress, however how it adapts to OS is not known. Here, we made an attempt to understand adaptation of C. glabrata to an oxidative environment by analyzing transcriptomic data.

All the observations have been reported in paper entitled: Transcriptomic analysis reveals global and temporal transcription changes during Candida glabrata adaptation to an oxidative environment.

Linked here are the scripts used to analyze and generate figures in the entitled study.

Author

Pooja Sethiya

Koon Ho Wong’s lab, University of Macau

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Oxidative stress response of Candida glabrata.

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