Mechanism for activation of OR6A/B/P/Y receptors by aldehydes. #390
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This is dependent on #391. |
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Predictions are running on the server for octanal and decanal. If both ligands show up as agonists on this page: http://primaryodors.net/receptor.php?r=OR6A2 then this PR can be closed. |
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TODO: Check the best-binding pairs. It is assigning both aldehydes to Ser260 instead of Lys164. |
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Operating under the hypothesis that the active motion of TMR6 brings Arg6.57 into contact with Asp5.39, freeing Lys4.60 for ligand binding.
Require ability to reconnect broken strands before proceeding.