Repositories list

• segdup-caller

  Public
  Specialized handling for difficult genes

  Python

  •

  BSD 2-Clause "Simplified" License

  •11 fork•77 stars•11 issue•00 pull requests•Updated Apr 25, 2026Apr 25, 2026

• sentieon-cli

  Public
  A command-line interface for Sentieon pipelines

  Python

  •

  BSD 2-Clause "Simplified" License

  •44 forks•1414 stars•00 issues•00 pull requests•Updated Apr 22, 2026Apr 22, 2026

• sentieon-amazon-omics

  Public
  Sentieon pipelines for AWS HealthOmics

  WDL

  •

  BSD 2-Clause "Simplified" License

  •44 forks•88 stars•00 issues•00 pull requests•Updated Apr 21, 2026Apr 21, 2026

• terraform

  Public
  Terraform configuration files for the Sentieon software

  HCL

  •

  BSD 2-Clause "Simplified" License

  •22 forks•11 star•00 issues•00 pull requests•Updated Apr 13, 2026Apr 13, 2026

• vcflib

  Public
  An open-source Python library for parsing and manipulation of VCF

  Python

  •

  BSD 2-Clause "Simplified" License

  •22 forks•99 stars•00 issues•00 pull requests•Updated Apr 9, 2026Apr 9, 2026

• sentieon-models

  Public
  Model files for Sentieon variant callers

  44 forks•1616 stars•00 issues•00 pull requests•Updated Apr 6, 2026Apr 6, 2026

• sentieon-scripts

  Public
  Helper scripts for biological data processing from Sentieon

  Shell

  •

  BSD 2-Clause "Simplified" License

  •2323 forks•6565 stars•22 issues•00 pull requests•Updated Apr 3, 2026Apr 3, 2026

• sentieon-docker

  Public
  Example Dockerfiles for use with the Sentieon software

  dockerfilessentieonsentieon-docker

  dockerfilessentieonsentieon-docker

  Dockerfile

  •

  BSD 2-Clause "Simplified" License

  •66 forks•99 stars•00 issues•00 pull requests•Updated Apr 3, 2026Apr 3, 2026

• KMC

  Public
  Fast and frugal disk based k-mer counter

  C++

  •8383 forks•00 stars•00 issues•00 pull requests•Updated Jan 5, 2026Jan 5, 2026

• hap-eval

  Public
  A VCF comparison engine for structual variant benchmarking

  Python

  •

  BSD 2-Clause "Simplified" License

  •44 forks•2424 stars•44 issues•11 pull request•Updated Sep 26, 2025Sep 26, 2025

• sentieon-google-genomics

  Public archive
  Run Sentieon pipelines on Google Cloud Platform

  somatic-variantsgcpbioinformatics-pipeline+ 6

  somatic-variantsgcpbioinformatics-pipelinecloud-computingspeedupgenomic-data-analysisngs-pipelinegermline-variantssentieon

  Shell

  •

  BSD 2-Clause "Simplified" License

  •77 forks•77 stars•00 issues•00 pull requests•Updated Aug 4, 2025Aug 4, 2025

• sentieon-dnascope-ml

  Public
  Sentieon DNAscope + Machine Learning Model

  machine-learningnext-generation-sequencingdna+ 6

  machine-learningnext-generation-sequencingdnabioinformatics-pipelinevariant-callinggermline-variantssentieongenomics-datadnascope

  Shell

  •44 forks•1212 stars•11 issue•00 pull requests•Updated Mar 19, 2025Mar 19, 2025

• aws-benchmark-scripts

  Public
  Scripts used in benchmarking Sentieon DNAseq and DNAscope pipelines on AWS EC2

  Python

  •33 forks•55 stars•00 issues•00 pull requests•Updated Jan 25, 2024Jan 25, 2024

• Sentieon-WDL

  Public
  WDL pipelines for the Sentieon tools

  wdl-workflowsentieonccdg+ 2

  wdl-workflowsentieonccdgfunctional-equivalent-pipelinefastq2vcf

  WDL

  •

  BSD 2-Clause "Simplified" License

  •22 forks•99 stars•00 issues•00 pull requests•Updated Dec 29, 2022Dec 29, 2022

• sentieon-matching-performance

  Public
  Accuracy and runtime benchmarks for the Sentieon GATK-matching tools

  Shell

  •

  BSD 2-Clause "Simplified" License

  •33 forks•66 stars•00 issues•00 pull requests•Updated Mar 19, 2021Mar 19, 2021

• sentieon-dnaseq

  Public archive
  Sentieon DNAseq

  accelerationgatkbioinformatics-pipeline+ 7

  accelerationgatkbioinformatics-pipelinevariant-callingdnaseqbwa-memdna-sequencingsentieongatk4genomics-data

  Shell

  •1313 forks•2323 stars•00 issues•00 pull requests•Updated Dec 30, 2020Dec 30, 2020

• Sentieon-cwl

  Public
  CWL pipelines for the Sentieon tools

  distributed-computingngs-pipelinesentieon+ 2

  distributed-computingngs-pipelinesentieoncwl-standardstoil-supports

  Common Workflow Language

  •

  BSD 2-Clause "Simplified" License

  •22 forks•44 stars•00 issues•00 pull requests•Updated Oct 22, 2018Oct 22, 2018

• toil

  Public
  A scalable, efficient, cross-platform and easy-to-use workflow engine in pure Python

  Python

  •

  Apache License 2.0

  •244244 forks•00 stars•00 issues•00 pull requests•Updated Jun 12, 2018Jun 12, 2018