Error: cannot execute binary file

[ftwtp1]

Hi all,

I am new to bioinformatics and to this community so I apologise in the advance if the way I write things are vague/not clear or if I miss out on some important details. (or if I ask naive/stupid questions)

I am trying to run bwakit on my Mac (M2 Ultra) and bumped into a problem and am seeking for advice.
So I mainly followed what is written on this page (https://github.com/lh3/bwa/blob/master/bwakit/README.md) and followed the following script.

#Download the bwa-0.7.11 binary package (download link may change)
wget -O- http://sourceforge.net/projects/bio-bwa/files/bwakit/bwakit-0.7.12_x64-linux.tar.bz2/download
| gzip -dc | tar xf -
#Generate the GRCh38+ALT+decoy+HLA and create the BWA index
bwa.kit/run-gen-ref hs38DH # download GRCh38 and write hs38DH.fa
bwa.kit/bwa index hs38DH.fa # create BWA index
#mapping
bwa.kit/run-bwamem -o out -H hs38DH.fa read1.fq read2.fq | sh

When I run the last command for the mapping I get the following warning.

WARNING: many programs require read groups. Please specify with -R if you can.
sh: line 1: bwa.kit/seqtk: cannot execute binary file
sh: line 3: bwa.kit/samtools: cannot execute binary file

How can I make this executable?

I appreciate your help and thank you in advance for your time!

[lh3]

That is x64 only