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tried out laynii, looks promising, but looks like metric leaks a bit
where it shouldn't (e.g. into DG from near srlm)..
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akhanf committed Jan 13, 2025
1 parent d9edaf2 commit cebfbcd
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Showing 5 changed files with 122 additions and 86 deletions.
8 changes: 4 additions & 4 deletions hippunfold/config/snakebids.yml
Original file line number Diff line number Diff line change
Expand Up @@ -231,10 +231,10 @@ parse_args:
--laminar_coords_method:
choices:
- 'laplace'
- 'equivolume'
default:
- 'equivolume'
help: 'Method to use for laminar coordinates. Equivolume uses equivolumetric layering from Waehnert et al 2014 (Nighres implementation). (default: %(default)s)'
- 'equivol'
- 'equidist'
default: 'equivol'
help: 'Method to use for laminar coordinates. Equivol and equidist are from the laynii LN2_LAYERS tool. (default: %(default)s)'

--autotop_labels:
choices:
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170 changes: 112 additions & 58 deletions hippunfold/workflow/rules/autotop.smk
Original file line number Diff line number Diff line change
Expand Up @@ -126,98 +126,152 @@ rule laplace_coords_dentate:
shell:
"cp {input} {output}"


rule prep_equivolume_coords:
rule morphclose_dg:
input:
get_labels_for_laplace,
params:
src_labels=lambda wildcards: config["laplace_labels"][wildcards.dir]["src"],
dseg_tissue=get_labels_for_laplace,
output:
outerbin=bids(
dseg_tissue=bids(
root=work,
datatype="coords",
dir="{dir}",
desc="all",
suffix="mask.nii.gz",
datatype="anat",
**inputs.subj_wildcards,
suffix="dseg.nii.gz",
desc="closeDG",
space="corobl",
hemi="{hemi}",
**inputs.subj_wildcards
hemi="{hemi}"
),
innerbin=bids(
group: 'subj'
container:
config["singularity"]["autotop"]
shell:
"c3d {input} -as DSEG -retain-labels 8 -binarize -dilate 1 3x3x3vox -erode 1 3x3x3vox -scale 100 -push DSEG -max -replace 100 8 -o {output}"

rule prep_dseg_for_laynii_hipp:
input:
dseg_tissue=bids(
root=work,
datatype="coords",
dir="{dir}",
desc="SRLM",
suffix="mask.nii.gz",
datatype="anat",
**inputs.subj_wildcards,
suffix="dseg.nii.gz",
desc="closeDG",
space="corobl",
hemi="{hemi}",
**inputs.subj_wildcards
hemi="{hemi}"
),
log:
bids(
root="logs",
params:
gm_labels=lambda wildcards: " ".join(
[str(lbl) for lbl in config["laplace_labels"][wildcards.dir]["gm_noDG"]]
),
src_labels=lambda wildcards: " ".join(
[str(lbl) for lbl in config["laplace_labels"][wildcards.dir]["src"]]
),
sink_labels=lambda wildcards: " ".join(
[str(lbl) for lbl in config["laplace_labels"][wildcards.dir]["sink"]]
),
output:
dseg_rim=bids(
root=work,
datatype="anat",
**inputs.subj_wildcards,
dir="{dir}",
hemi="{hemi}",
suffix="binarize.txt"
suffix="dseg.nii.gz",
dir="{dir,IO}",
desc="laynii",
label="{autotop,hipp}",
space="corobl",
hemi="{hemi}"
),
container:
config["singularity"]["autotop"]
group:
"subj"
shell:
"c3d -background -1 {input} -as DSEG -retain-labels {params.gm_labels} -binarize -scale 3 -popas GM -push DSEG -retain-labels {params.src_labels} -binarize -scale 2 -popas WM -push DSEG -retain-labels {params.sink_labels} -binarize -scale 1 -popas PIAL -push GM -push WM -add -push PIAL -add -o {output}"


rule prep_dseg_for_laynii_dentate:
input:
dseg_tissue=bids(
root=work,
datatype="anat",
**inputs.subj_wildcards,
suffix="dseg.nii.gz",
desc="closeDG",
space="corobl",
hemi="{hemi}"
),
params:
gm_labels=lambda wildcards: " ".join(
[str(lbl) for lbl in [8]]
),
src_labels=lambda wildcards: " ".join(
[str(lbl) for lbl in [2,4,7,0] ]
),
sink_labels=lambda wildcards: " ".join(
[str(lbl) for lbl in [1]]
),
output:
dseg_rim=bids(
root=work,
datatype="anat",
**inputs.subj_wildcards,
suffix="dseg.nii.gz",
dir="{dir,IO}",
desc="laynii",
label="{autotop,dentate}",
space="corobl",
hemi="{hemi}"
),
container:
config["singularity"]["autotop"]
script:
"../scripts/prep_equivolume_coords.py"
group:
"subj"
shell:
"c3d -background -1 {input} -as DSEG -retain-labels {params.gm_labels} -binarize -scale 3 -popas GM -push DSEG -retain-labels {params.src_labels} -binarize -scale 2 -popas WM -push DSEG -retain-labels {params.sink_labels} -binarize -scale 1 -popas PIAL -push GM -push WM -add -push PIAL -add -o {output}"


rule equivolume_coords:

rule laynii_layers:
input:
outerbin=bids(
dseg_rim=bids(
root=work,
datatype="coords",
datatype="anat",
**inputs.subj_wildcards,
suffix="dseg.nii.gz",
dir="{dir}",
desc="all",
suffix="mask.nii.gz",
desc="laynii",
label="{autotop}",
space="corobl",
hemi="{hemi}",
**inputs.subj_wildcards
hemi="{hemi}"
),
innerbin=bids(
output:
equivol=bids(
root=work,
datatype="coords",
dir="{dir}",
desc="SRLM",
suffix="mask.nii.gz",
dir="{dir,IO}",
label="{autotop}",
suffix="coords.nii.gz",
desc="equivol",
space="corobl",
hemi="{hemi}",
**inputs.subj_wildcards
),
params:
script=os.path.join(workflow.basedir, "scripts/equivolume_coords.py"),
output:
coords=bids(
equidist=bids(
root=work,
datatype="coords",
dir="{dir}",
label="hipp",
dir="{dir,IO}",
label="{autotop}",
suffix="coords.nii.gz",
desc="equivol",
desc="equidist",
space="corobl",
hemi="{hemi}",
**inputs.subj_wildcards
),
shadow:
"minimal"
container:
config["singularity"]["autotop"]
group:
"subj"
resources:
time=30,
log:
bids(
root="logs",
**inputs.subj_wildcards,
dir="{dir}",
hemi="{hemi}",
suffix="equivolume.txt"
),
container:
config["singularity"]["autotop"]
shell:
"python {params.script} {resources.tmpdir} {input.innerbin} {input.outerbin} {output.coords} &> {log}"
"cp {input} dseg.nii.gz && "
"LN2_LAYERS -rim dseg.nii.gz -equivol && "
"cp dseg_metric_equidist.nii.gz {output.equidist} && "
"cp dseg_metric_equivol.nii.gz {output.equivol}"
9 changes: 2 additions & 7 deletions hippunfold/workflow/rules/common.smk
Original file line number Diff line number Diff line change
Expand Up @@ -123,11 +123,6 @@ def get_final_subfields():


def get_final_coords():
if "laplace" in config["laminar_coords_method"]:
desc_io = "laplace"
elif "equivolume" in config["laminar_coords_method"]:
desc_io = "equivol"

coords = []
# compute all laplace coords by default (incl IO)
coords.extend(
Expand All @@ -144,7 +139,7 @@ def get_final_coords():
**inputs.subj_wildcards,
),
desc="laplace",
dir=["AP", "PD", "IO"],
dir=["AP", "PD"],
autotop=config["autotop_labels"],
hemi=config["hemi"],
space=crop_ref_spaces,
Expand All @@ -164,7 +159,7 @@ def get_final_coords():
label="hipp",
**inputs.subj_wildcards,
),
desc=[desc_io],
desc=config['laminar_coords_method'],
dir=["IO"],
hemi=config["hemi"],
space=crop_ref_spaces,
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2 changes: 1 addition & 1 deletion hippunfold/workflow/rules/native_surf.smk
Original file line number Diff line number Diff line change
Expand Up @@ -30,7 +30,7 @@ nan_labels = {
}

desc_io = {
"hipp": "equivol" if "equivolume" in config["laminar_coords_method"] else "laplace",
"hipp": config["laminar_coords_method"],
"dentate": "laplace",
}

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19 changes: 3 additions & 16 deletions hippunfold/workflow/rules/warps.smk
Original file line number Diff line number Diff line change
Expand Up @@ -286,31 +286,18 @@ rule create_unfold_coord_map:


def get_laminar_coords(wildcards):
if "laplace" in config["laminar_coords_method"]:
coords_io = bids(

return bids(
root=work,
datatype="coords",
dir="IO",
label="hipp",
suffix="coords.nii.gz",
desc="laplace",
space="corobl",
hemi="{hemi}",
**inputs.subj_wildcards
)
elif "equivolume" in config["laminar_coords_method"]:
coords_io = bids(
root=work,
datatype="coords",
dir="IO",
label="hipp",
suffix="coords.nii.gz",
desc="equivol",
desc=config["laminar_coords_method"],
space="corobl",
hemi="{hemi}",
**inputs.subj_wildcards
)
return coords_io


rule create_warps_hipp:
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