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henriksson-lab/malaria_crispr2024

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This is an interactive Shiny-based app that visualises the analysed data for CRISPR screens using the PbHiT system in the rodent malaria parasite Plasmodium berghei” as described in Jonsdottir et al. DOI: https://doi.org/10.1101/2024.04.20.590404

Generated by the Bushell lab at Umeå University. http://www.bushelllab.com/

License

MIT license

Files

  • count.R -- takes all FASTQ files and outputs count matrices
  • grstats.R -- takes count files and generates statistics
  • crispr_methods_paper.R -- generates plots for the paper
  • crispr_pools/* -- processed count files and metadata

These are related to the shiny app:

  • global.R -- Load files into memory
  • server.R -- Server backend
  • start.R -- For starting the server
  • Makefile -- For starting the server
  • ui.R -- User interface declaration

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