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📦 🔬 R/adaptest: Data-Adaptive Procedures for Multiple Hypothesis Testing in High-Dimensional Biology

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R/adaptest

Travis-CI Build Status AppVeyor Build Status Coverage Status Project Status: WIP – Initial development is in progress, but there has not yet been a stable, usable release suitable for the public. GPL-2 License JOSS status

Data-adaptive statistics for multiple testing in high-dimensional problems

Authors: Wilson Cai and Nima Hejazi


What’s adaptest?

The adaptest R package is a tool for performing multiple testing on effect sizes under high-dimensional settings, using the approach of data-adaptive statistical target parameters and inference. For technical details on the data-adaptive multiple testing procedure, consult Cai, Hejazi, and Hubbard. For an introduction to statistical inference procedures using data-adaptive target parameters, the interested reader is directed to Hubbard, Kherad-Pajouh, and van der Laan (2016).


Installation

Install the most recent stable release from GitHub via devtools:

devtools::install_github("wilsoncai1992/adaptest")

Issues

If you encounter any bugs or have any specific feature requests, please file an issue.


Contributions

It is our hope that adaptest will grow to be widely adopted as a tool for employing data-adaptive multiple hypothesis testing procedures in high-dimensional and complex problem settings. To that end, contributions are very welcome, though we ask that interested contributors consult our contribution guidelines prior to submitting a pull request.


Citation

After using the adaptest R package, please cite it:

  @article{cai2017adaptest,
    doi = {},
    url = {},
    year  = {2017},
    month = {},
    publisher = {The Open Journal},
    volume = {submitted},
    number = {},
    author = {Cai, Weixin and Hubbard, Alan E and Hejazi, Nima S},
    title = {adaptest: Data-Adaptive Statistics for High-Dimensional Testing
      in R},
    journal = {The Journal of Open Source Software}
  }

License

The software contents of this repository are distributed under the GPL-2 license. See file LICENSE for details.


References

Cai, Weixin, Nima S Hejazi, and Alan E Hubbard. “Data-Adaptive Statistics for Multiple Hypothesis Testing in High-Dimensional Settings.” https://arxiv.org/abs/1704.07008.

Hubbard, Alan E, Sara Kherad-Pajouh, and Mark J van der Laan. 2016. “Statistical Inference for Data Adaptive Target Parameters.” The International Journal of Biostatistics 12 (1): 3–19.

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