Motivation: The idea for this repository comes from my experience during my PhD, where I spent a lot of time and energy searching for resources that are normally freely accessible but sometimes hard to find. Primarily, if you are new to or transitioning into the field of Alzheimer's research, I hope this could help you to have a good starting point and save your time.
So, I decided to share what I would call a complete collection of materials and resources for Alzheimer's disease research, which will, of course, continue to grow to support research and everyone interested or working in this field.
I will continuously share more about my current research, therefore stay tuned. ✌️
- Databases & Data Repositories
- Research Organizations & Initiatives
- Genetic Resources
- Biomarker Research
- Neuroimaging Resources
- Clinical Trials & Studies
- Research Tools
- Funding Opportunities
- Publications & Journals
- Educational Resources
- Software & Computational Tools
- Animal Models
- Patient Data & Cohorts
- Open Science Resources
- Alzheimer's Disease Neuroimaging Initiative (ADNI) - Longitudinal multicenter study designed to develop clinical, imaging, genetic, and biochemical biomarkers for the early detection and tracking of Alzheimer's disease
- Alzheimer's Disease Sequencing Project (ADSP) - Large-scale sequencing analysis of genomes of individuals with Alzheimer's disease
- AlzGPS - A genome-wide positioning systems platform for Alzheimer's disease drug discovery
- AlzPED - Alzheimer's Preclinical Efficacy Database for evaluation of preclinical therapy development
- NIAGADS - NIA Genetics of Alzheimer's Disease Data Storage Site
- Alzheimer's Disease Data Initiative (ADDI) - Global platform to accelerate discoveries and innovations in Alzheimer's disease and related dementias
- AMP-AD Knowledge Portal - Data, tools, and resources for the study of Alzheimer's disease
- Allen Brain Atlas - Comprehensive atlas of gene expression in the adult and developing brain
- Human Brain Project - European research initiative aiming to build a collaborative ICT-based scientific research infrastructure
- BRAIN Initiative - Revolutionary project aimed at developing innovative technologies to understand the human brain
- OpenNeuro - Free and open platform for sharing neuroimaging data
- Proteomics DB - Database of human proteome information
- PRIDE Archive - Repository of mass spectrometry proteomics data
- Metabolomics Workbench - Repository for metabolomics data and metadata
- National Institute on Aging (NIA) - US federal agency supporting Alzheimer's research
- National Institute of Neurological Disorders and Stroke (NINDS) - US agency funding research on neurological disorders
- European Medicines Agency (EMA) - EU agency for the evaluation of medicinal products
- Alzheimer's Association - Largest nonprofit funder of Alzheimer's research
- Alzheimer's Research UK - UK's leading dementia research charity
- Alzheimer's Foundation of America - Organization providing support, services, and education
- Cure Alzheimer's Fund - Non-profit funding targeted research with potential for breakthrough results
- World Health Organization (WHO) Dementia Action Plan - Global action plan on the public health response to dementia
- International Alzheimer's Disease Research Portfolio (IADRP) - Database of funded Alzheimer's disease research projects
- JPND Research - EU Joint Programme on Neurodegenerative Disease Research
- DIAN (Dominantly Inherited Alzheimer Network) - International research partnership studying dominantly inherited Alzheimer's disease
- EADB (European Alzheimer's Disease Biobank) - Large-scale biobanking initiative
- MODEL-AD - Center developing next-generation mouse models of Alzheimer's disease
- AIBL (Australian Imaging, Biomarkers and Lifestyle Study) - Study of biomarkers, cognitive characteristics, and lifestyle factors
- AlzGene - Database of genetic association studies in Alzheimer's disease
- AD Genetics Database - Comprehensive, unbiased, publicly available database of genetic association studies
- GWAS Catalog - Catalog of genome-wide association studies
- gnomAD - Genome Aggregation Database for population genetics
- ClinVar - Database of genetic variations and their clinical significance
- PLINK - Whole genome association analysis toolset
- ANNOVAR - Functional annotation of genetic variants
- PolyPhen-2 - Tool for prediction of possible impact of amino acid substitutions
- Alzheimer's Disease Knowledge Portal - Platform for accessing and analyzing genomic data
- Blood-Based Biomarker Interest Group - Alzheimer's Association initiative for blood biomarkers
- Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium - Public-private partnership for biomarker development
- Alzheimer's Association QC Program for CSF Biomarkers - Quality control program for CSF biomarker measurements
- CSF Biomarker Database - Database of published CSF biomarker performance
- Biomarkers for Alzheimer's Disease Research Summit - NIA initiative for biomarker standardization
- Global Biomarker Standardization Consortium - International effort to standardize biomarker tests
- ADNI MRI Protocols - Standardized MRI protocols for Alzheimer's disease research
- UK Biobank Imaging - Large-scale population imaging dataset
- Human Connectome Project - Mapping of human brain connectivity
- Centiloid Project - Standardization of amyloid PET measures
- ADNI PET Protocols - Standardized PET protocols for Alzheimer's disease research
- Tau PET Consortium - International collaboration on tau imaging
- FreeSurfer - Software suite for processing and analyzing brain MRI images
- FSL - Library of analysis tools for brain imaging data
- SPM - Statistical Parametric Mapping software
- AFNI - Analysis of Functional NeuroImages software
- ClinicalTrials.gov - Registry of clinical trials
- EU Clinical Trials Register - European registry of clinical trials
- ISRCTN Registry - Primary clinical trial registry
- Alzheimer's Disease Clinical Trials Database - Alzheimer's Association's database of clinical trials
- FDA Guidance for Alzheimer's Disease Drug Development - Regulatory guidance for Alzheimer's drug development
- EMA Guidelines on Alzheimer's Disease - European regulatory guidelines
- ICHOM Standard Set for Dementia - Standardized outcome measures for dementia
- A4 Study (Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease) - Testing anti-amyloid treatment in asymptomatic individuals
- DIAN-TU (Dominantly Inherited Alzheimer Network Trials Unit) - Clinical trials in autosomal dominant Alzheimer's disease
- API (Alzheimer's Prevention Initiative) - Evaluating treatments to prevent Alzheimer's disease
- MMSE (Mini-Mental State Examination) - Brief cognitive assessment tool
- MoCA (Montreal Cognitive Assessment) - Cognitive screening test
- CDR (Clinical Dementia Rating) - Scale for staging dementia severity
- ADAS-Cog (Alzheimer's Disease Assessment Scale-Cognitive Subscale) - Cognitive assessment tool
- Digital Cognitive Assessment Tools - Computerized cognitive testing
- Brain Health Registry - Online registry for brain health research
- C2N Diagnostics - Blood tests for Alzheimer's disease
- Cogstate - Digital cognitive assessments
- NIA Biospecimen Best Practice Guidelines - Guidelines for biospecimen collection and processing
- Alzheimer's Disease Biospecimen Collection Protocol - Standardized protocols for biospecimen collection
- NIH Funding Opportunities - US federal funding for research
- NIA Alzheimer's Disease Research Centers - Network of centers providing funding and resources
- European Commission Horizon Europe - EU research and innovation funding program
- UK Research and Innovation (UKRI) - UK's main research funding body
- Alzheimer's Association Research Grants - Various funding opportunities
- BrightFocus Foundation - Funding for Alzheimer's disease research
- Cure Alzheimer's Fund Research Grants - Funding for breakthrough research
- Alzheimer's Drug Discovery Foundation (ADDF) - Funding for drug discovery and development
- Gates Ventures - Funding from the Bill & Melinda Gates Foundation
- Pharmaceutical Research and Manufacturers of America (PhRMA) - Industry funding opportunities
- Alzheimer's & Dementia - Official journal of the Alzheimer's Association
- Journal of Alzheimer's Disease - International multidisciplinary journal
- Neurobiology of Aging - Fundamental age-related research
- Alzheimer's Research & Therapy - Open access journal for Alzheimer's research
- Nature Reviews Neurology - Reviews on neurological diseases
- JAMA Neurology - Peer-reviewed medical journal on neurology
- Cochrane Database of Systematic Reviews - Systematic reviews of healthcare interventions
- PROSPERO - International prospective register of systematic reviews
- Alzheimer's Association TrialMatch - Educational resources about clinical trials
- National Institute on Aging Training Resources - Training and education for researchers
- Coursera Neuroscience Courses - Online courses on neuroscience
- edX Neuroscience Courses - Free online courses from top universities
- AAIC (Alzheimer's Association International Conference) - Annual conference on Alzheimer's research
- CTAD (Clinical Trials on Alzheimer's Disease) - Conference focused on clinical trials
- ADPD (Alzheimer's & Parkinson's Diseases Conference) - Conference on neurodegenerative diseases
- Society for Neuroscience Annual Meeting - Large neuroscience conference
- NIA Training Programs - Career development and training opportunities
- Alzheimer's Association Research Fellowships - Research training fellowships
- AgeUK Dementia Training - Training for healthcare professionals
- R Statistical Software - Free software for statistical computing
- Python with Pandas - Data analysis library for Python
- MATLAB - Platform for numerical computation and visualization
- GraphPad Prism - Statistical analysis and graphing software
- Bioconductor - Open source software for bioinformatics
- Galaxy - Web-based platform for data intensive biomedical research
- CytoScape - Open source software for visualizing molecular interaction networks
- RStudio - Integrated development environment for R
- TensorFlow - Open source machine learning framework
- PyTorch - Machine learning library
- scikit-learn - Machine learning in Python
- Keras - Deep learning API
- REDCap - Secure web application for building and managing databases
- MongoDB - NoSQL database program
- PostgreSQL - Advanced open source database
- The Jackson Laboratory Alzheimer's Models - Mouse models for Alzheimer's research
- Alzforum Research Models - Database of animal models
- Charles River Laboratories - Provider of research models
- MODEL-AD - Next generation mouse models of Alzheimer's disease
- iPSC Neurodegenerative Disease Initiative - iPSC models for neurodegeneration
- Allen Cell Types Database - Multimodal characterization of cell types in the brain
- 3D Brain Cell Atlas - Comprehensive RNA-Seq data of brain cells
- National Cell Repository for Alzheimer's Disease - Repository for cell lines and DNA samples
- Alzheimer's Disease Neuroimaging Initiative (ADNI) Animal Data - Preclinical animal imaging data
- Religious Orders Study and Rush Memory and Aging Project (ROSMAP) - Two longitudinal clinical-pathologic cohort studies
- Harvard Aging Brain Study - Longitudinal study of aging and Alzheimer's disease
- Mayo Clinic Study of Aging - Population-based study of cognitive aging
- Baltimore Longitudinal Study of Aging (BLSA) - America's longest-running scientific study of human aging
- Minority Aging Research Study (MARS) - Study focusing on African American cognitive aging
- Washington Heights-Inwood Columbia Aging Project (WHICAP) - Multiethnic community study
- Health and Retirement Study (HRS) - Panel study of older Americans
- UK Biobank - Large-scale biomedical database and research resource
- NIH NeuroBioBank - Federally funded network of brain and tissue repositories
- BrainNet Europe - Network of European brain banks
- PubMed Central - Archive of biomedical and life sciences journal literature
- Europe PMC - Repository of life science articles and preprints
- Zenodo - Open access repository for research papers, data, and software
- Open Science Framework - Platform for research project management and collaboration
- GitHub - Platform for software development and sharing
- Sage Bionetworks Synapse - Platform for data-driven collaborative research
- AMP-AD Knowledge Portal - Portal for the Accelerating Medicines Partnership
- GAAIN (Global Alzheimer's Association Interactive Network) - Global big data platform for Alzheimer's disease
- ADDI Workbench - Integrated data sharing platform