Update Log

We have fixed some problem observed in the beta version of 2.2.12
a. Clumping now function as expected
b. Standard error calculated should now always be correct
Fix problem where PRSice doesn't honor the --model setting
Fix INFO score and MAF filtering in the base
Fix output of the --no-regress. --no-regress should now also generate a *.prsice file which contains the number of SNPs included in the PRS
Fix problem related to set-based permutation
- We also now drastically speed up set based permutation when the --ultra option is used (Require more memory).
PRSice should now be able to handle special characters in the base file
Add --num-auto. User can now change the number of autosome in their samples (Note: we assume all autosome to be diploid)
Add --keep-ambig-as-is. When set, ambiguous SNPs that were kept will never be flipped. This should allow for slightly better control for the user
Completely remove --pearson as we don't have the manpower to maintain this feature
Also remove --enable-mmap as that doesn't help too much

Note

Window builds are completely failing and I have no idea why. We will try to figure out the problem but it is unlikely that it will be anytime soon. As a result of that, the window build will be unavailable until further noticed.
Currently, due to the flexibility of PRSice, there are large amount of functions that need to be tested before we can be confident for PRSice to work as expected. Therefore, I am hoping that until we complete the unit test for all feature of PRSice (which is extremely time consuming, and our current coverage is less than 5%), we will not add in any new features.