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Add Multiple or Custom Enzymes #273
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@jackrogan this is not supported. Yet, we will give priority for next release. Can you let me know which dataset do you have in mind that can help us to test. |
Yes, it is a bit complicated. In theory, we need to model any order of enzymes and add an option to allow for simultaneous application. While e.g. Comet supports this, many other search engines do not. |
I know already that when I'm using enzymes different that Trypsin, I need to enable only As you said similar approach can be followed for multiple enzymes, only allow Comet when multiple enzymes is needed. |
I don't have any data yet - I'm still working out how to analyse a planned experiment. |
Trypsin/P should work. Please open another issue for this. |
Description of feature
Is it possible to run a search with multiple enzymes, or to add a custom enzyme (in this case with the appropriate cleaving locations expected for a 2-enzyme digestion?)
If it helps, the digestions I'm interested in running are Trypsin + Asp-N and Trypsin + Glu-C.
Thanks!
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