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<a href=#event-format><svg width="16" height="16" fill="currentcolor" class="bi bi-link" viewBox="0 0 16 16"><path d="M6.354 5.5H4a3 3 0 000 6h3a3 3 0 002.83-4H9c-.086.0-.17.01-.25.031A2 2 0 017 10.5H4a2 2 0 110-4h1.535c.218-.376.495-.714.82-1z"/><path d="M9 5.5a3 3 0 00-2.83 4h1.098A2 2 0 019 6.5h3a2 2 0 110 4h-1.535a4.02 4.02.0 01-.82 1H12a3 3 0 100-6H9z"/></svg></a></h1><p>Each monthly Open Science Forum event will be a one-hour webinar featuring two short scientific talks followed by an optional 30-minute moderated discussion with the speakers:</p><p><strong>Science talks (recorded, webinar format)</strong></p><ul><li>Talk 1 : 25 minutes + 5 minutes Q&amp;A</li><li>Talk 2 : 25 minutes + 5 minutes Q&amp;A</li></ul><p><strong>Moderated discussion with speakers (unrecorded, Zoom meeting format)</strong></p><ul><li>Talk 1 : 30 minutes</li></ul><p>Each recorded talk will be posted online after the event, along with relevant links to publications, data, reagents, or other resources discussed by the speaker that may be useful in disseminating resources or reagents for global antiviral discovery.</p><h1 id=mailing-list>Mailing list
<a href=#mailing-list><svg width="16" height="16" fill="currentcolor" class="bi bi-link" viewBox="0 0 16 16"><path d="M6.354 5.5H4a3 3 0 000 6h3a3 3 0 002.83-4H9c-.086.0-.17.01-.25.031A2 2 0 017 10.5H4a2 2 0 110-4h1.535c.218-.376.495-.714.82-1z"/><path d="M9 5.5a3 3 0 00-2.83 4h1.098A2 2 0 019 6.5h3a2 2 0 110 4h-1.535a4.02 4.02.0 01-.82 1H12a3 3 0 100-6H9z"/></svg></a></h1><p>To receive invitations to events and other news items, <a href="https://asapdiscovery.us10.list-manage.com/subscribe?u=fd04e028b883a3832b2fbc61d&amp;id=1ba169f53a">sign up for the Antiviral Drug Discovery (AViDD) Open Science Forum mailing list</a>.</p><h1 id=schedule>Schedule
<a href=#schedule><svg width="16" height="16" fill="currentcolor" class="bi bi-link" viewBox="0 0 16 16"><path d="M6.354 5.5H4a3 3 0 000 6h3a3 3 0 002.83-4H9c-.086.0-.17.01-.25.031A2 2 0 017 10.5H4a2 2 0 110-4h1.535c.218-.376.495-.714.82-1z"/><path d="M9 5.5a3 3 0 00-2.83 4h1.098A2 2 0 019 6.5h3a2 2 0 110 4h-1.535a4.02 4.02.0 01-.82 1H12a3 3 0 100-6H9z"/></svg></a></h1><p>The Open Science Forum will hold virtual events the <strong>third Wednesday of every month</strong>:</p><p><strong>Wed 19 February 2025</strong>: <em>8.00A PT / 11.00A ET / 4.00P UK (GMT+1) / 5.00P Geneva (GMT+2)</em> <strong><a href=https://meetmsk.zoom.us/webinar/register/WN_4Xbqx8MMS4-7p8poMEmnDw>[Register Here]</a></strong>
<a name=2025-feb></a><br><em>Moderator:</em> <a href=https://web.stanford.edu/group/kirkegaard/karla.html><strong>Karla Kirkegaard</strong></a> (<a href=https://www.stanford.edu/>Stanford University</a>)</p><ul><li><strong><a href=https://sites.google.com/site/kielianlab/>Margaret Kielian</a> (<a href=https://einsteinmed.edu/>Albert Einstein College of Medicine</a>) (<a href=https://acdc-virus.org/>AC/DC</a>) and <a href=https://medschool.cuanschutz.edu/immunology-and-microbiology/immu-micro-labs/morrison-lab>Thomas Morrison</a> (<a href=https://www.cuanschutz.edu/>University of Colorado, Anschutz</a>)</strong>: <em>4′-fluorouridine inhibition of alphavirus replication and infection in vitro and in vivo</em></li><li><strong>TBD</strong></li></ul><p><strong>Wed 19 March 2025</strong>: <em>8.00A PT / 11.00A ET / 4.00P UK (GMT+1) / 5.00P Geneva (GMT+2)</em> <strong><a href=https://meetmsk.zoom.us/webinar/register/WN_4Xbqx8MMS4-7p8poMEmnDw>[Register Here]</a></strong>
<a name=2025-march></a><br><em>Moderator:</em> <a href=https://dndi.org/our-people/peter-sjo/><strong>Peter Sjö</strong></a> (<a href=http://dndi.org>DNDi</a>)</p><ul><li><strong><a href=https://www.diamond.ac.uk/Home.html>Anu Chandran and Jasmin Aschenbrenner, Diamond Light Source</a></strong>: <em>Crystallographic Fragment Screening of RNA-Dependent RNA Polymerase Domains as a Foundation for Developing Pan-Flavivirus Therapeutics</em></li><li><strong><a href=https://dr.ntu.edu.sg/cris/rp/rp01058>Nam-Joon Cho, Nanyang Technological University</a></strong>: <em>TBD</em></li></ul><h1 id=past-presentations>Past Presentations
<a name=2025-feb></a><br><em>Moderator:</em> <a href=https://web.stanford.edu/group/kirkegaard/karla.html><strong>Karla Kirkegaard</strong></a> (<a href=https://www.stanford.edu/>Stanford University</a>)</p><ul><li><strong><a href=https://sites.google.com/site/kielianlab/>Margaret Kielian</a> (<a href=https://einsteinmed.edu/>Albert Einstein College of Medicine</a>) (<a href=https://acdc-virus.org/>AC/DC</a>) and <a href=https://medschool.cuanschutz.edu/immunology-and-microbiology/immu-micro-labs/morrison-lab>Thomas Morrison</a> (<a href=https://www.cuanschutz.edu/>University of Colorado, Anschutz</a>)</strong>: <em>4′-fluorouridine inhibition of alphavirus replication and infection in vitro and in vivo</em></li><li><strong><a href=https://www.cheme.columbia.edu/faculty/jingyue-ju>Jingyue Ju, Columbia University</a> (<a href=https://mavdaresearch.org/en>MAVDA</a>)</strong>: <em>Discovery and Optimization of RNA Synthesis Inhibitors for Coronavirus and Other Viruses of Pandemic Potential</em></li></ul><p><strong>Wed 19 March 2025</strong>: <em>8.00A PT / 11.00A ET / 4.00P UK (GMT+1) / 5.00P Geneva (GMT+2)</em> <strong><a href=https://meetmsk.zoom.us/webinar/register/WN_4Xbqx8MMS4-7p8poMEmnDw>[Register Here]</a></strong>
<a name=2025-march></a><br><em>Moderator:</em> <a href=https://dndi.org/our-people/peter-sjo/><strong>Peter Sjö</strong></a> (<a href=http://dndi.org>DNDi</a>)</p><ul><li><strong><a href=https://www.diamond.ac.uk/Home.html>Anu Chandran and Jasmin Aschenbrenner, Diamond Light Source</a> (<a href=http://asapdiscovery.org>ASAP</a>)</strong>: <em>Crystallographic Fragment Screening of RNA-Dependent RNA Polymerase Domains as a Foundation for Developing Pan-Flavivirus Therapeutics</em></li><li><strong><a href=https://dr.ntu.edu.sg/cris/rp/rp01058>Nam-Joon Cho, Nanyang Technological University</a></strong>: <em>TBD</em></li></ul><h1 id=past-presentations>Past Presentations
<a href=#past-presentations><svg width="16" height="16" fill="currentcolor" class="bi bi-link" viewBox="0 0 16 16"><path d="M6.354 5.5H4a3 3 0 000 6h3a3 3 0 002.83-4H9c-.086.0-.17.01-.25.031A2 2 0 017 10.5H4a2 2 0 110-4h1.535c.218-.376.495-.714.82-1z"/><path d="M9 5.5a3 3 0 00-2.83 4h1.098A2 2 0 019 6.5h3a2 2 0 110 4h-1.535a4.02 4.02.0 01-.82 1H12a3 3 0 100-6H9z"/></svg></a></h1><p>All talk videos are archived on <a href=https://www.youtube.com/@AViDD-OSF>Youtube</a> and slides are archived at <a href=https://zenodo.org/communities/open-antivirals/>Zenodo</a>.</p><p><strong>Wed 15 January 2025</strong>: <em>8.00A PT / 11.00A ET / 4.00P UK (GMT+1) / 5.00P Geneva (GMT+2)</em> <strong><a href=https://meetmsk.zoom.us/webinar/register/WN_4Xbqx8MMS4-7p8poMEmnDw>[Register Here]</a></strong>
<a name=2025-jan></a><br><em>Moderator:</em> <a href=https://www.diamond.ac.uk/Home.html><strong>Frank von Delft</strong></a> (<a href=https://www.diamond.ac.uk/Instruments/Mx/Fragment-Screening.html>Diamond Light Source</a>)</p><ul><li><strong><a href=https://www.med.upenn.edu/cherrylab/>Sara Cherry, University of Pennsylvania</a> (<a href=https://www.campp.org/>CAMPP</a>) (<a href=https://readdi.org/>READDI-AC</a>)</strong>: <em>Identifying antivirals active against emerging RNA viruses</em> <strong><a href=https://youtu.be/oKEp-mAgaac>[Video]</a></strong></li><li><strong><a href=https://pharm.ucsf.edu/craik>Charles Craik, University of California San Francisco</a> (<a href=https://qcrg.ucsf.edu/qcrg-avidd-overview>QCRG</a>)</strong>: <em>Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus-MPro inhibitors with potent in vivo efficacy</em> <strong><a href=https://youtu.be/kjv9xlG_Oeg>[Video]</a></strong></li></ul><p><strong>Wed 18 December 2024</strong>: <em>8.00A PT / 11.00A ET / 4.00P UK (GMT+1) / 5.00P Geneva (GMT+2)</em>
<a name=2024-dec></a><br><em>Moderator:</em> <a href=https://www.choderalab.org/><strong>John Chodera</strong></a> (<a href=https://www.mskcc.org/>MSKCC</a>)</p><ul><li><strong><a href=https://pharmacy.unc.edu/research/centers/sgc-unc/people/>Peter Brown, UNC Chapel Hill</a> (<a href=https://readdi.org/>READDI-AC</a>)</strong>: <em>A Covalent Chemical Probe for Chikungunya nsP2 Cysteine Protease</em> <strong><a href=https://www.researchsquare.com/article/rs-5363451/v1>[Preprint]</a></strong> <strong><a href=https://youtu.be/ceiIc2A1oy8>[Video]</a></strong></li><li><strong><a href=https://meihonglab.com/professor-mei-hong/>Mei Hong, Massachusetts Institute of Technology</a> (<a href=https://qcrg.ucsf.edu/qcrg-avidd-overview>QCRG</a>)</strong>: <em>Structures and Drug Binding of the SARS-CoV-2 Envelope Protein from Solid-State NMR</em> <strong><a href=https://youtu.be/KaZ8xnfRwjw>[Video]</a></strong></li></ul><p><strong>Wed 20 November 2024</strong>: <em>8.00A PT / 11.00A ET / 4.00P UK (GMT+1) / 5.00P Geneva (GMT+2)</em>
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