Skip to content

set of scripts and pipelines to work with QTL results

Notifications You must be signed in to change notification settings

RajLabMSSM/downstream-QTL

Folders and files

NameName
Last commit message
Last commit date

Latest commit

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Repository files navigation

downstream-QTL

Pipelines for working with QTL results. Assumes QTLs were mapped using QTL-mapping-pipeline and both QTL and GWAS summary statistics have been placed into the Raj Lab GWAS/QTL Database.

Written by Jack Humphrey and Katia de Paiva Lopes Raj Lab 2020

  • Scripts for wrangling GWAS summary stats (GWAS)

  • Colocalisation with GWAS results (COLOC)

  • Pairwise sharing between QTLs (qvalue_sharing, pisquared)

  • Random-effects meta-analysis of multiple QTL datasets (METASOFT)

  • Multivariate adaptive shrinkage for sharing of effect sizes between QTL datasets (MASHR)

  • Building Transcriptome-wide Association Study models and applying them to GWAS (TWAS) - under construction

  • Fine-mapping using the echolocatoR pipeline (Fine-mapping)

About

set of scripts and pipelines to work with QTL results

Resources

Stars

Watchers

Forks

Packages

No packages published

Contributors 3

  •  
  •  
  •  

Languages