ezmtt is a package for analyzing MTT assay data - namely, fitting and plotting curves and calculating IC%.
It mainly serves as a ‘companion package’ for the protocol here, but is flexible enough to support a variety of plate layouts.
You can install the development version of ezmtt from GitHub with:
# install.packages("devtools")
devtools::install_github("KaiAragaki/ezmtt")library(ezmtt)
mtt |>
mtt_fit(
conditions = list(
drug_a = c(0, 1, 10, 100, 1000, 10000),
drug_b = c(0, 1, 10, 100, 1000, 10000),
NA,
NA
),
model = c("ll", "lm")
) |>
mtt_plot(ic_pct = 50)
#> Lowest dose is 0, converting to 1e-04
#> Lowest dose is 0, converting to 1e-04