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Simulations of circadian amplitude

This repository contains the code needed to generate the figures in "Beyond phase shifting: Amplitude as a target for circadian light interventions" by Olivia Walch, Franco Tavella, Jamie Zeitzer, and Renske Lok.

Figure 1, which shows phase and amplitude response curves, can be found in the ipynb notebooks amplitude_boost_simulations.ipynb and amplitude_boost_plots.ipynb.

Figure 2, which shows how more light tends to hit during the amplitude suppression region as sleep irregularity increases is in make_sleep_irregularity_figure.py

Figure 3, which is an explainer image for two definitions of amplitude, is generated by make_melatonin_figure.py

All figures can be made by running the Jupyter notebooks and then running make_all_figures.py

The repository also contains some code for analyzing how different day lengths and light brightnesses affect circadian amplitude, as well as a simple model for melatonin production on permanent DST and permanent ST. These are in the more_simulations directory.

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