diff --git a/pyproject.toml b/pyproject.toml
index 1544f76..fba512b 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -14,7 +14,7 @@ readme = "README.md"
 license = {text = "GPL-3.0"}
 requires-python = ">=3.8"
 dependencies = [
-    "zigpy>=0.60.0",
+    "zigpy>=0.60.2",
 ]
 
 [tool.setuptools.packages.find]
diff --git a/zigpy_xbee/api.py b/zigpy_xbee/api.py
index b4a73da..ffad765 100644
--- a/zigpy_xbee/api.py
+++ b/zigpy_xbee/api.py
@@ -8,6 +8,7 @@
 
 import serial
 from zigpy.config import CONF_DEVICE_PATH, SCHEMA_DEVICE
+from zigpy.datastructures import PriorityLock
 from zigpy.exceptions import APIException, DeliveryError
 import zigpy.types as t
 
@@ -289,6 +290,7 @@ def __init__(self, device_config: Dict[str, Any]) -> None:
         self._cmd_mode_future: Optional[asyncio.Future] = None
         self._reset: asyncio.Event = asyncio.Event()
         self._running: asyncio.Event = asyncio.Event()
+        self._send_lock = PriorityLock()
 
     @property
     def reset_event(self):
@@ -333,20 +335,31 @@ def close(self):
             self._uart.close()
             self._uart = None
 
-    def _command(self, name, *args, mask_frame_id=False):
+    def _get_command_priority(self, name: str, *args) -> int:
+        return {
+            "tx_explicit": -1,
+            "remote_at": -1,
+        }.get(name, 0)
+
+    async def _command(self, name, *args, mask_frame_id=False):
         """Send API frame to the device."""
-        LOGGER.debug("Command %s %s", name, args)
         if self._uart is None:
             raise APIException("API is not running")
-        frame_id = 0 if mask_frame_id else self._seq
-        data, needs_response = self._api_frame(name, frame_id, *args)
-        self._uart.send(data)
-        future = None
-        if needs_response and frame_id:
+
+        async with self._send_lock(priority=self._get_command_priority(name)):
+            LOGGER.debug("Command %s %s", name, args)
+            frame_id = 0 if mask_frame_id else self._seq
+            data, needs_response = self._api_frame(name, frame_id, *args)
+            self._uart.send(data)
+
+            if not needs_response or not frame_id:
+                return
+
             future = asyncio.Future()
             self._awaiting[frame_id] = (future,)
-        self._seq = (self._seq % 255) + 1
-        return future
+            self._seq = (self._seq % 255) + 1
+
+            return await future
 
     async def _remote_at_command(self, ieee, nwk, options, name, *args):
         """Execute AT command on a different XBee module in the network."""
@@ -597,9 +610,3 @@ async def _probe(self) -> None:
                 raise APIException("Failed to configure XBee for API mode")
         finally:
             self.close()
-
-    def __getattr__(self, item):
-        """Handle supported command requests."""
-        if item in COMMAND_REQUESTS:
-            return functools.partial(self._command, item)
-        raise AttributeError(f"Unknown command {item}")
diff --git a/zigpy_xbee/zigbee/application.py b/zigpy_xbee/zigbee/application.py
index 2158b95..55f0ffe 100644
--- a/zigpy_xbee/zigbee/application.py
+++ b/zigpy_xbee/zigbee/application.py
@@ -302,29 +302,31 @@ async def send_packet(self, packet: zigpy.types.ZigbeePacket) -> None:
                 "Cannot send a packet to a device without a known IEEE address"
             )
 
-        send_req = self._api.tx_explicit(
-            long_addr,
-            short_addr,
-            packet.src_ep or 0,
-            packet.dst_ep or 0,
-            packet.cluster_id,
-            packet.profile_id,
-            packet.radius,
-            tx_opts,
-            packet.data.serialize(),
-        )
-
-        try:
-            v = await asyncio.wait_for(send_req, timeout=TIMEOUT_TX_STATUS)
-        except asyncio.TimeoutError:
-            raise zigpy.exceptions.DeliveryError(
-                "Timeout waiting for ACK", status=TXStatus.NETWORK_ACK_FAILURE
+        async with self._limit_concurrency():
+            send_req = self._api._command(
+                "tx_explicit",
+                long_addr,
+                short_addr,
+                packet.src_ep or 0,
+                packet.dst_ep or 0,
+                packet.cluster_id,
+                packet.profile_id,
+                packet.radius,
+                tx_opts,
+                packet.data.serialize(),
             )
 
-        if v != TXStatus.SUCCESS:
-            raise zigpy.exceptions.DeliveryError(
-                f"Failed to deliver packet: {v!r}", status=v
-            )
+            try:
+                v = await asyncio.wait_for(send_req, timeout=TIMEOUT_TX_STATUS)
+            except asyncio.TimeoutError:
+                raise zigpy.exceptions.DeliveryError(
+                    "Timeout waiting for ACK", status=TXStatus.NETWORK_ACK_FAILURE
+                )
+
+            if v != TXStatus.SUCCESS:
+                raise zigpy.exceptions.DeliveryError(
+                    f"Failed to deliver packet: {v!r}", status=v
+                )
 
     @zigpy.util.retryable_request()
     def remote_at_command(
@@ -356,7 +358,9 @@ async def permit_with_link_key(
         # Key type:
         # 0 = Pre-configured Link Key (KY command of the joining device)
         # 1 = Install Code With CRC (I? command of the joining device)
-        await self._api.register_joining_device(node, reserved, key_type, link_key)
+        await self._api._command(
+            "register_joining_device", node, reserved, key_type, link_key
+        )
 
     def handle_modem_status(self, status):
         """Handle changed Modem Status of the device."""