diff --git a/worker/include/RTC/PipeConsumer.hpp b/worker/include/RTC/PipeConsumer.hpp
index 39066f4140..5a3e646467 100644
--- a/worker/include/RTC/PipeConsumer.hpp
+++ b/worker/include/RTC/PipeConsumer.hpp
@@ -73,7 +73,8 @@ namespace RTC
 		absl::flat_hash_map<uint32_t, RTC::RtpStreamSend*> mapSsrcRtpStream;
 		bool keyFrameSupported{ false };
 		absl::flat_hash_map<RTC::RtpStreamSend*, bool> mapRtpStreamSyncRequired;
-		absl::flat_hash_map<RTC::RtpStreamSend*, RTC::SeqManager<uint16_t>> mapRtpStreamRtpSeqManager;
+		absl::flat_hash_map<RTC::RtpStreamSend*, std::unique_ptr<RTC::SeqManager<uint16_t>>>
+		  mapRtpStreamRtpSeqManager;
 	};
 } // namespace RTC
 
diff --git a/worker/include/RTC/SimulcastConsumer.hpp b/worker/include/RTC/SimulcastConsumer.hpp
index fcce57adb4..70c328971c 100644
--- a/worker/include/RTC/SimulcastConsumer.hpp
+++ b/worker/include/RTC/SimulcastConsumer.hpp
@@ -115,7 +115,7 @@ namespace RTC
 		bool syncRequired{ false };
 		int16_t spatialLayerToSync{ -1 };
 		bool lastSentPacketHasMarker{ false };
-		RTC::SeqManager<uint16_t> rtpSeqManager;
+		std::unique_ptr<RTC::SeqManager<uint16_t>> rtpSeqManager;
 		int16_t preferredSpatialLayer{ -1 };
 		int16_t preferredTemporalLayer{ -1 };
 		int16_t provisionalTargetSpatialLayer{ -1 };
diff --git a/worker/include/RTC/SvcConsumer.hpp b/worker/include/RTC/SvcConsumer.hpp
index c61220293f..cb860709d6 100644
--- a/worker/include/RTC/SvcConsumer.hpp
+++ b/worker/include/RTC/SvcConsumer.hpp
@@ -100,7 +100,7 @@ namespace RTC
 		std::vector<RTC::RtpStreamSend*> rtpStreams;
 		RTC::RtpStreamRecv* producerRtpStream{ nullptr };
 		bool syncRequired{ false };
-		RTC::SeqManager<uint16_t> rtpSeqManager;
+		std::unique_ptr<RTC::SeqManager<uint16_t>> rtpSeqManager;
 		int16_t preferredSpatialLayer{ -1 };
 		int16_t preferredTemporalLayer{ -1 };
 		int16_t provisionalTargetSpatialLayer{ -1 };
diff --git a/worker/src/RTC/PipeConsumer.cpp b/worker/src/RTC/PipeConsumer.cpp
index cde4fbfc76..fa25ef885b 100644
--- a/worker/src/RTC/PipeConsumer.cpp
+++ b/worker/src/RTC/PipeConsumer.cpp
@@ -4,6 +4,7 @@
 #include "RTC/PipeConsumer.hpp"
 #include "Logger.hpp"
 #include "MediaSoupErrors.hpp"
+#include "Utils.hpp"
 #include "RTC/Codecs/Tools.hpp"
 
 namespace RTC
@@ -264,7 +265,7 @@ namespace RTC
 		// Packets with only padding are not forwarded.
 		if (packet->GetPayloadLength() == 0)
 		{
-			rtpSeqManager.Drop(packet->GetSequenceNumber());
+			rtpSeqManager->Drop(packet->GetSequenceNumber());
 
 #ifdef MS_RTC_LOGGER_RTP
 			packet->logger.Dropped(RtcLogger::RtpPacket::DropReason::EMPTY_PAYLOAD);
@@ -284,7 +285,7 @@ namespace RTC
 				MS_DEBUG_TAG(rtp, "sync key frame received");
 			}
 
-			rtpSeqManager.Sync(packet->GetSequenceNumber() - 1);
+			rtpSeqManager->Sync(packet->GetSequenceNumber() - 1);
 
 			syncRequired = false;
 		}
@@ -292,7 +293,7 @@ namespace RTC
 		// Update RTP seq number and timestamp.
 		uint16_t seq;
 
-		rtpSeqManager.Input(packet->GetSequenceNumber(), seq);
+		rtpSeqManager->Input(packet->GetSequenceNumber(), seq);
 
 		// Save original packet fields.
 		auto origSsrc = packet->GetSsrc();
@@ -680,7 +681,15 @@ namespace RTC
 			this->mapMappedSsrcSsrc[consumableEncoding.ssrc] = encoding.ssrc;
 			this->mapSsrcRtpStream[encoding.ssrc]            = rtpStream;
 			this->mapRtpStreamSyncRequired[rtpStream]        = false;
-			this->mapRtpStreamRtpSeqManager[rtpStream];
+
+			// Let's chosee an initial output seq number between 1000 and 32768 to avoid
+			// libsrtp bug:
+			// https://github.com/versatica/mediasoup/issues/1437
+			const uint16_t initialOutputSeq =
+			  Utils::Crypto::GetRandomUInt(1000u, std::numeric_limits<uint16_t>::max() / 2);
+
+			this->mapRtpStreamRtpSeqManager[rtpStream].reset(
+			  new RTC::SeqManager<uint16_t>(initialOutputSeq));
 		}
 	}
 
diff --git a/worker/src/RTC/SimulcastConsumer.cpp b/worker/src/RTC/SimulcastConsumer.cpp
index bc54bf3424..fcd60c1c5f 100644
--- a/worker/src/RTC/SimulcastConsumer.cpp
+++ b/worker/src/RTC/SimulcastConsumer.cpp
@@ -5,6 +5,7 @@
 #include "DepLibUV.hpp"
 #include "Logger.hpp"
 #include "MediaSoupErrors.hpp"
+#include "Utils.hpp"
 #include "RTC/Codecs/Tools.hpp"
 
 namespace RTC
@@ -98,6 +99,14 @@ namespace RTC
 			  "%s codec not supported for simulcast", mediaCodec->mimeType.ToString().c_str());
 		}
 
+		// Let's chosee an initial output seq number between 1000 and 32768 to avoid
+		// libsrtp bug:
+		// https://github.com/versatica/mediasoup/issues/1437
+		const uint16_t initialOutputSeq =
+		  Utils::Crypto::GetRandomUInt(1000u, std::numeric_limits<uint16_t>::max() / 2);
+
+		this->rtpSeqManager.reset(new RTC::SeqManager<uint16_t>(initialOutputSeq));
+
 		RTC::Codecs::EncodingContext::Params params;
 
 		params.spatialLayers  = encoding.spatialLayers;
@@ -802,7 +811,7 @@ namespace RTC
 		// not have payload other than padding, then drop it.
 		if (spatialLayer == this->currentSpatialLayer && packet->GetPayloadLength() == 0)
 		{
-			this->rtpSeqManager.Drop(packet->GetSequenceNumber());
+			this->rtpSeqManager->Drop(packet->GetSequenceNumber());
 
 #ifdef MS_RTC_LOGGER_RTP
 			packet->logger.Dropped(RtcLogger::RtpPacket::DropReason::EMPTY_PAYLOAD);
@@ -951,7 +960,7 @@ namespace RTC
 			// 'packet->GetSequenceNumber() -2' may increase SeqManager::base and
 			// increase the output sequence number.
 			// https://github.com/versatica/mediasoup/issues/408
-			this->rtpSeqManager.Sync(packet->GetSequenceNumber() - (this->lastSentPacketHasMarker ? 1 : 2));
+			this->rtpSeqManager->Sync(packet->GetSequenceNumber() - (this->lastSentPacketHasMarker ? 1 : 2));
 
 			this->encodingContext->SyncRequired();
 
@@ -1013,7 +1022,7 @@ namespace RTC
 			// Rewrite payload if needed. Drop packet if necessary.
 			if (!packet->ProcessPayload(this->encodingContext.get(), marker))
 			{
-				this->rtpSeqManager.Drop(packet->GetSequenceNumber());
+				this->rtpSeqManager->Drop(packet->GetSequenceNumber());
 
 #ifdef MS_RTC_LOGGER_RTP
 				packet->logger.Dropped(RtcLogger::RtpPacket::DropReason::DROPPED_BY_CODEC);
@@ -1032,7 +1041,7 @@ namespace RTC
 		uint16_t seq;
 		const uint32_t timestamp = packet->GetTimestamp() - this->tsOffset;
 
-		this->rtpSeqManager.Input(packet->GetSequenceNumber(), seq);
+		this->rtpSeqManager->Input(packet->GetSequenceNumber(), seq);
 
 		// Save original packet fields.
 		auto origSsrc      = packet->GetSsrc();
@@ -1066,7 +1075,7 @@ namespace RTC
 		// Process the packet.
 		if (this->rtpStream->ReceivePacket(packet, sharedPacket))
 		{
-			if (this->rtpSeqManager.GetMaxOutput() == packet->GetSequenceNumber())
+			if (this->rtpSeqManager->GetMaxOutput() == packet->GetSequenceNumber())
 			{
 				this->lastSentPacketHasMarker = packet->HasMarker();
 			}
diff --git a/worker/src/RTC/SvcConsumer.cpp b/worker/src/RTC/SvcConsumer.cpp
index a2337b4f81..d5fb24d750 100644
--- a/worker/src/RTC/SvcConsumer.cpp
+++ b/worker/src/RTC/SvcConsumer.cpp
@@ -5,6 +5,7 @@
 #include "DepLibUV.hpp"
 #include "Logger.hpp"
 #include "MediaSoupErrors.hpp"
+#include "Utils.hpp"
 #include "RTC/Codecs/Tools.hpp"
 
 namespace RTC
@@ -79,6 +80,14 @@ namespace RTC
 			MS_THROW_TYPE_ERROR("%s codec not supported for svc", mediaCodec->mimeType.ToString().c_str());
 		}
 
+		// Let's chosee an initial output seq number between 1000 and 32768 to avoid
+		// libsrtp bug:
+		// https://github.com/versatica/mediasoup/issues/1437
+		const uint16_t initialOutputSeq =
+		  Utils::Crypto::GetRandomUInt(1000u, std::numeric_limits<uint16_t>::max() / 2);
+
+		this->rtpSeqManager.reset(new RTC::SeqManager<uint16_t>(initialOutputSeq));
+
 		RTC::Codecs::EncodingContext::Params params;
 
 		params.spatialLayers  = encoding.spatialLayers;
@@ -681,7 +690,7 @@ namespace RTC
 		// Packets with only padding are not forwarded.
 		if (packet->GetPayloadLength() == 0)
 		{
-			this->rtpSeqManager.Drop(packet->GetSequenceNumber());
+			this->rtpSeqManager->Drop(packet->GetSequenceNumber());
 
 #ifdef MS_RTC_LOGGER_RTP
 			packet->logger.Dropped(RtcLogger::RtpPacket::DropReason::EMPTY_PAYLOAD);
@@ -701,7 +710,7 @@ namespace RTC
 				MS_DEBUG_TAG(rtp, "sync key frame received");
 			}
 
-			this->rtpSeqManager.Sync(packet->GetSequenceNumber() - 1);
+			this->rtpSeqManager->Sync(packet->GetSequenceNumber() - 1);
 			this->encodingContext->SyncRequired();
 
 			this->syncRequired = false;
@@ -715,7 +724,7 @@ namespace RTC
 
 		if (!packet->ProcessPayload(this->encodingContext.get(), marker))
 		{
-			this->rtpSeqManager.Drop(packet->GetSequenceNumber());
+			this->rtpSeqManager->Drop(packet->GetSequenceNumber());
 
 #ifdef MS_RTC_LOGGER_RTP
 			packet->logger.Dropped(RtcLogger::RtpPacket::DropReason::DROPPED_BY_CODEC);
@@ -738,7 +747,7 @@ namespace RTC
 		// Update RTP seq number and timestamp based on NTP offset.
 		uint16_t seq;
 
-		this->rtpSeqManager.Input(packet->GetSequenceNumber(), seq);
+		this->rtpSeqManager->Input(packet->GetSequenceNumber(), seq);
 
 		// Save original packet fields.
 		auto origSsrc = packet->GetSsrc();