diff --git a/packages/bruno-cli/src/commands/run.js b/packages/bruno-cli/src/commands/run.js
index 29edf63b9c..4f82a86e69 100644
--- a/packages/bruno-cli/src/commands/run.js
+++ b/packages/bruno-cli/src/commands/run.js
@@ -11,6 +11,7 @@ const { rpad } = require('../utils/common');
 const { bruToJson, getOptions, collectionBruToJson } = require('../utils/bru');
 const { dotenvToJson } = require('@usebruno/lang');
 const constants = require('../constants');
+const { findItemInCollection } = require('../utils/collection');
 const command = 'run [filename]';
 const desc = 'Run a request';
 
@@ -18,6 +19,7 @@ const printRunSummary = (results) => {
   let totalRequests = 0;
   let passedRequests = 0;
   let failedRequests = 0;
+  let skippedRequests = 0;
   let totalAssertions = 0;
   let passedAssertions = 0;
   let failedAssertions = 0;
@@ -49,7 +51,10 @@ const printRunSummary = (results) => {
         failedAssertions += 1;
       }
     }
-    if (!hasAnyTestsOrAssertions && result.error) {
+    if (!hasAnyTestsOrAssertions && result.skipped) {
+      skippedRequests += 1;
+    }
+    else if (!hasAnyTestsOrAssertions && result.error) {
       failedRequests += 1;
     } else {
       passedRequests += 1;
@@ -62,6 +67,9 @@ const printRunSummary = (results) => {
   if (failedRequests > 0) {
     requestSummary += `, ${chalk.red(`${failedRequests} failed`)}`;
   }
+  if (skippedRequests > 0) {
+    requestSummary += `, ${chalk.magenta(`${skippedRequests} skipped`)}`;
+  }
   requestSummary += `, ${totalRequests} total`;
 
   let assertSummary = `${rpad('Tests:', maxLength)} ${chalk.green(`${passedTests} passed`)}`;
@@ -84,6 +92,7 @@ const printRunSummary = (results) => {
     totalRequests,
     passedRequests,
     failedRequests,
+    skippedRequests,
     totalAssertions,
     passedAssertions,
     failedAssertions,
@@ -144,7 +153,7 @@ const createCollectionFromPath = (collectionPath) => {
           });
         }
       }
-      return currentDirItems
+      return currentDirItems;
     };
     collection.items = traverse(collectionPath);
     return collection;
@@ -634,6 +643,34 @@ const handler = async function (argv) {
     }
 
     const runtime = getJsSandboxRuntime(sandbox);
+
+    const runSingleRequestByPathname = async (relativeItemPathname) => {
+      return new Promise(async (resolve, reject) => {
+        let itemPathname = path.join(collectionPath, relativeItemPathname);
+        if (itemPathname && !itemPathname?.endsWith('.bru')) {
+          itemPathname = `${itemPathname}.bru`;
+        }
+        const bruJson = cloneDeep(findItemInCollection(collection, itemPathname));
+        if (bruJson) {
+          const res = await runSingleRequest(
+            itemPathname,
+            bruJson,
+            collectionPath,
+            runtimeVariables,
+            envVars,
+            processEnvVars,
+            brunoConfig,
+            collectionRoot,
+            runtime,
+            collection,
+            runSingleRequestByPathname
+          );
+          resolve(res?.response);
+        }
+        reject(`bru.runRequest: invalid request path - ${itemPathname}`);
+      });
+    }
+
     let currentRequestIndex = 0;
     let nJumps = 0; // count the number of jumps to avoid infinite loops
     while (currentRequestIndex < bruJsons.length) {
@@ -651,7 +688,8 @@ const handler = async function (argv) {
         brunoConfig,
         collectionRoot,
         runtime,
-        collection
+        collection,
+        runSingleRequestByPathname
       );
 
       results.push({
@@ -701,6 +739,11 @@ const handler = async function (argv) {
 
       // determine next request
       const nextRequestName = result?.nextRequestName;
+
+      if (result?.shouldStopRunnerExecution) {
+        break;
+      }
+      
       if (nextRequestName !== undefined) {
         nJumps++;
         if (nJumps > 10000) {
diff --git a/packages/bruno-cli/src/runner/run-single-request.js b/packages/bruno-cli/src/runner/run-single-request.js
index 29ed749b94..0d1787273e 100644
--- a/packages/bruno-cli/src/runner/run-single-request.js
+++ b/packages/bruno-cli/src/runner/run-single-request.js
@@ -38,11 +38,13 @@ const runSingleRequest = async function (
   brunoConfig,
   collectionRoot,
   runtime,
-  collection
+  collection,
+  runSingleRequestByPathname
 ) {
   try {
     let request;
     let nextRequestName;
+    let shouldStopRunnerExecution = false;
     let item = {
       pathname: path.join(collectionPath, filename),
       ...bruJson
@@ -66,11 +68,41 @@ const runSingleRequest = async function (
         collectionPath,
         onConsoleLog,
         processEnvVars,
-        scriptingConfig
+        scriptingConfig,
+        runSingleRequestByPathname
       );
       if (result?.nextRequestName !== undefined) {
         nextRequestName = result.nextRequestName;
       }
+
+      if (result?.stopExecution) {
+        shouldStopRunnerExecution = true;
+      }
+
+      if (result?.skipRequest) {
+        return {
+          test: {
+            filename: filename
+          },
+          request: {
+            method: request.method,
+            url: request.url,
+            headers: request.headers,
+            data: request.data
+          },
+          response: {
+            status: 'skipped',
+            statusText: 'request skipped via pre-request script',
+            data: null,
+            responseTime: 0
+          },
+          error: 'Request has been skipped from pre-request script',
+          skipped: true,
+          assertionResults: [],
+          testResults: [],
+          shouldStopRunnerExecution
+        };
+      }
     }
 
     // interpolate variables inside request
@@ -316,7 +348,8 @@ const runSingleRequest = async function (
           error: err?.message || err?.errors?.map(e => e?.message)?.at(0) || err?.code || 'Request Failed!',
           assertionResults: [],
           testResults: [],
-          nextRequestName: nextRequestName
+          nextRequestName: nextRequestName,
+          shouldStopRunnerExecution
         };
       }
     }
@@ -356,11 +389,16 @@ const runSingleRequest = async function (
         collectionPath,
         null,
         processEnvVars,
-        scriptingConfig
+        scriptingConfig,
+        runSingleRequestByPathname
       );
       if (result?.nextRequestName !== undefined) {
         nextRequestName = result.nextRequestName;
       }
+
+      if (result?.stopExecution) {
+        shouldStopRunnerExecution = true;
+      }
     }
 
     // run assertions
@@ -401,13 +439,18 @@ const runSingleRequest = async function (
         collectionPath,
         null,
         processEnvVars,
-        scriptingConfig
+        scriptingConfig,
+        runSingleRequestByPathname
       );
       testResults = get(result, 'results', []);
 
       if (result?.nextRequestName !== undefined) {
         nextRequestName = result.nextRequestName;
       }
+
+      if (result?.stopExecution) {
+        shouldStopRunnerExecution = true;
+      }
     }
 
     if (testResults?.length) {
@@ -440,7 +483,8 @@ const runSingleRequest = async function (
       error: null,
       assertionResults,
       testResults,
-      nextRequestName: nextRequestName
+      nextRequestName: nextRequestName,
+      shouldStopRunnerExecution
     };
   } catch (err) {
     console.log(chalk.red(stripExtension(filename)) + chalk.dim(` (${err.message})`));
diff --git a/packages/bruno-cli/src/utils/collection.js b/packages/bruno-cli/src/utils/collection.js
index 365732c488..64e17cb39b 100644
--- a/packages/bruno-cli/src/utils/collection.js
+++ b/packages/bruno-cli/src/utils/collection.js
@@ -204,5 +204,6 @@ module.exports = {
   mergeHeaders,
   mergeVars,
   mergeScripts,
+  findItemInCollection,
   getTreePathFromCollectionToItem
 }
\ No newline at end of file
diff --git a/packages/bruno-electron/src/ipc/network/index.js b/packages/bruno-electron/src/ipc/network/index.js
index 782878c59a..6ae5ef2208 100644
--- a/packages/bruno-electron/src/ipc/network/index.js
+++ b/packages/bruno-electron/src/ipc/network/index.js
@@ -544,7 +544,7 @@ const registerNetworkIpc = (mainWindow) => {
         if (itemPathname && !itemPathname?.endsWith('.bru')) {
           itemPathname = `${itemPathname}.bru`;
         }
-        const _item = findItemInCollectionByPathname(collection, itemPathname);
+        const _item = cloneDeep(findItemInCollectionByPathname(collection, itemPathname));
         if(_item) {
           const res = await runRequest({ item: _item, collection, environment, runtimeVariables, runInBackground: true });
           resolve(res);
@@ -952,7 +952,7 @@ const registerNetworkIpc = (mainWindow) => {
           if (itemPathname && !itemPathname?.endsWith('.bru')) {
             itemPathname = `${itemPathname}.bru`;
           }
-          const _item = findItemInCollectionByPathname(collection, itemPathname);
+          const _item = cloneDeep(findItemInCollectionByPathname(collection, itemPathname));
           if(_item) {
             const res = await runRequest({ item: _item, collection, environment, runtimeVariables, runInBackground: true });
             resolve(res);
diff --git a/packages/bruno-tests/collection/ping-another-one.bru b/packages/bruno-tests/collection/ping-another-one.bru
new file mode 100644
index 0000000000..84c1412a84
--- /dev/null
+++ b/packages/bruno-tests/collection/ping-another-one.bru
@@ -0,0 +1,15 @@
+meta {
+  name: ping-another-one
+  type: http
+  seq: 2
+}
+
+get {
+  url: {{host}}/ping
+  body: none
+  auth: none
+}
+
+script:pre-request {
+  throw new Error('this should not execute in a collection run');
+}
diff --git a/packages/bruno-tests/collection/ping.bru b/packages/bruno-tests/collection/ping.bru
index 3abc7a2d41..8f4f3c6f72 100644
--- a/packages/bruno-tests/collection/ping.bru
+++ b/packages/bruno-tests/collection/ping.bru
@@ -9,3 +9,7 @@ get {
   body: none
   auth: none
 }
+
+script:pre-request {
+  bru.runner.stopExecution();
+}
diff --git a/packages/bruno-tests/collection/scripting/api/bru/runRequest.bru b/packages/bruno-tests/collection/scripting/api/bru/runRequest.bru
new file mode 100644
index 0000000000..7eb0e332cd
--- /dev/null
+++ b/packages/bruno-tests/collection/scripting/api/bru/runRequest.bru
@@ -0,0 +1,96 @@
+meta {
+  name: runRequest
+  type: http
+  seq: 2
+}
+
+post {
+  url: {{host}}/api/echo/json
+  body: json
+  auth: none
+}
+
+headers {
+  foo: bar
+}
+
+auth:basic {
+  username: asd
+  password: j
+}
+
+auth:bearer {
+  token: 
+}
+
+body:json {
+  {
+    "hello": "bruno"
+  }
+}
+
+assert {
+  res.status: eq 200
+}
+
+script:pre-request {
+  bru.setVar("runRequest-ping-res-1", null);
+  bru.setVar("runRequest-ping-res-2", null);
+  bru.setVar("runRequest-ping-res-3", null);
+  
+  let pingRes = await bru.runRequest('ping');
+  bru.setVar('runRequest-ping-res-1', {
+    data: pingRes?.data,
+    statusText: pingRes?.statusText,
+    status: pingRes?.status
+  });
+}
+
+script:post-response {
+  let pingRes = await bru.runRequest('ping');
+  bru.setVar('runRequest-ping-res-2', {
+    data: pingRes?.data,
+    statusText: pingRes?.statusText,
+    status: pingRes?.status
+  });
+}
+
+tests {
+  const pingRes = await bru.runRequest('ping');
+  bru.setVar('runRequest-ping-res-3', {
+    data: pingRes?.data,
+    statusText: pingRes?.statusText,
+    status: pingRes?.status
+  });
+  
+  test("should run request and return valid response in pre-request script", function() {
+    const expectedPingRes = {
+      data: "pong",
+      statusText: "OK",
+      status: 200
+    };
+    const pingRes = bru.getVar('runRequest-ping-res-1');
+    expect(pingRes).to.eql(expectedPingRes);
+  });
+  
+  test("should run request and return valid response in post-response script", function() {
+    const expectedPingRes = {
+      data: "pong",
+      statusText: "OK",
+      status: 200
+    };
+    const pingRes = bru.getVar('runRequest-ping-res-2');
+    expect(pingRes).to.eql(expectedPingRes);
+  });
+  
+  test("should run request and return valid response in tests script", function() {
+    const expectedPingRes = {
+      data: "pong",
+      statusText: "OK",
+      status: 200
+    };
+    const pingRes = bru.getVar('runRequest-ping-res-3');
+    expect(pingRes).to.eql(expectedPingRes);
+  });
+  
+}
diff --git a/packages/bruno-tests/collection/scripting/api/bru/runner/1.bru b/packages/bruno-tests/collection/scripting/api/bru/runner/1.bru
new file mode 100644
index 0000000000..97a7edbb6e
--- /dev/null
+++ b/packages/bruno-tests/collection/scripting/api/bru/runner/1.bru
@@ -0,0 +1,19 @@
+meta {
+  name: 1
+  type: http
+  seq: 1
+}
+
+post {
+  url: https://echo.usebruno.com
+  body: none
+  auth: none
+}
+
+script:pre-request {
+  bru.setVar('bru-runner-req', 1);
+}
+
+script:post-response {
+  bru.setVar('bru.runner.skipRequest', true);
+}
diff --git a/packages/bruno-tests/collection/scripting/api/bru/runner/2.bru b/packages/bruno-tests/collection/scripting/api/bru/runner/2.bru
new file mode 100644
index 0000000000..b1be74b22e
--- /dev/null
+++ b/packages/bruno-tests/collection/scripting/api/bru/runner/2.bru
@@ -0,0 +1,19 @@
+meta {
+  name: 2
+  type: http
+  seq: 2
+}
+
+post {
+  url: https://echo.usebruno.com
+  body: none
+  auth: none
+}
+
+script:pre-request {
+  bru.runner.skipRequest();
+}
+
+script:post-response {
+  bru.setVar('bru.runner.skipRequest', false);
+}
diff --git a/packages/bruno-tests/collection/scripting/api/bru/runner/3.bru b/packages/bruno-tests/collection/scripting/api/bru/runner/3.bru
new file mode 100644
index 0000000000..4ffe49315e
--- /dev/null
+++ b/packages/bruno-tests/collection/scripting/api/bru/runner/3.bru
@@ -0,0 +1,21 @@
+meta {
+  name: 3
+  type: http
+  seq: 3
+}
+
+post {
+  url: https://echo.usebruno.com
+  body: none
+  auth: none
+}
+
+script:pre-request {
+}
+
+tests {
+  test("should skip the previous request ('2')", function() {
+    const wasRequestSkipped = bru.getVar('bru.runner.skipRequest');
+    expect(wasRequestSkipped).to.eql(true);
+  });
+}