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Distance-based LD shrinkage #11

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xiangzhu opened this issue Aug 7, 2018 · 0 comments
Open

Distance-based LD shrinkage #11

xiangzhu opened this issue Aug 7, 2018 · 0 comments
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enhancement

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@xiangzhu
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xiangzhu commented Aug 7, 2018

I wonder how hard to add the following distance-based LD shrinkage estimator: LD(i, j) = 0 if SNP i and j are far away, say 10Mb apart.

This approach was used in GCTA-COJO paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593158/

screen shot 2018-08-06 at 9 15 50 pm
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