Different Genotype arrays for demultiplexing samples

[carolynmcgrail]

Hello,

We have samples that will be genotyped on different arrays, will this be a problem when demultiplexing due to less overlap of shared snps?

Thank you,
Carolyn

[hyunminkang]

I think so. I would recommend imputing the genotypes and extract high-quality (e.g. RSQ > 0.9) imputed genotypes in such cases. Thanks, Hyun. ----------------------------------------------------- Hyun Min Kang, Ph.D. Professor of Biostatistics University of Michigan, Ann Arbor Email : ***@***.***

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On Wed, Oct 5, 2022 at 1:23 PM carolynmcgrail ***@***.***> wrote: Hello, We have samples that will be genotyped on different arrays, will this be a problem when demultiplexing due to less overlap of shared snps? Thank you, Carolyn — Reply to this email directly, view it on GitHub <#96>, or unsubscribe <https://github.com/notifications/unsubscribe-auth/ABPY5OIQIVOSS6HFY6LIAVTWBW2QVANCNFSM6AAAAAAQ5YF6E4> . You are receiving this because you are subscribed to this thread.Message ID: ***@***.***>