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Applying Pre-Trained Perturb-Seq Models to scRNA-Seq Data #92

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BioSenior opened this issue Feb 20, 2025 · 0 comments
Open

Applying Pre-Trained Perturb-Seq Models to scRNA-Seq Data #92

BioSenior opened this issue Feb 20, 2025 · 0 comments

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@BioSenior
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Hi! Thanks for developing GEARS, which is an amazing tool for modeling transcriptional responses to perturbations.

I was wondering if one can use one of the pre-trained models (on Perturb-seq data) and apply them to scRNA-seq data to infer possible transcriptional response to a list of known/given perturbations; not to train the model per se but to apply the ones already trained on a different data source, despite them using different cell types and tissue just to inquire about possible similarities.

Thanks in advance!

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