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config.yaml
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config.yaml
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MODEL_PARAMETERS:
T_INITIAL: -21
T_FINAL: 7200
HEMODYNAMICS:
S_BLOOD_VOLUME: 5000
S_BLOOD_PRESSURE: 65
K_BASELINE_BLOOD_PRESSURE: 0.001
K_BLOOD_PRESSURE_NO: 1.0e-07
K_URINATE: 0.01
COAGULATION:
S_RBC: 5.0e9
K_BASELINE_RBC: 4.01127e-6
S_INACTIVE_COAG_FACTOR: 1.0e8
S_INACTIVE_ANTI_COAG: 4.0e6
S_ACTIVE_ANTI_COAG: 1.0e3
S_PLATELETS: 3
K_BASELINE_PLATELETS: 0.000120338
RBC_INFUSION_BONUS_CONC: 1.44
PLASMA_INFUSION_COAG_BONUS: 1.55
PLATELET_INFUSION_BONUS_CONC: 3.67
D_ACTIVE_COAG_FACTOR: 0.693314718
D_CLOT: 1.0e-5
K_ACTIVE_COAG_FACTOR_ACTIVE_ANTI_COAG_ENHANCE: 0.001
K_ACTIVE_COAG_FACTOR_ACTIVE_ANTI_COAG_COLLIDE: 0.001
K_PLATELET_SOURCE_ENHANCE: 0.001
K_COAG_FACTOR_ACTIVATION_TRAUMA: 1.0e-7
K_INACTIVE_ANTI_COAG_ACTIVE_COAG_FACTOR: 1.0e-7
K_CLOT: 1.0e-9
K_CLOT_RBC: 1.0e-7
K_BLEED_TRAUMA: 12
K_BLEED_CONTROL: 5.0e-4
K_FIBRINOLYSIS: 0.001
ACTIVECOAGFACTOR_PORTION_OF_CLOT_CONVERTER: 1
PLATELETS_PORTION_OF_CLOT_CONVERTER: 1
INFLAMMATION:
ALPHA_DAMP_SENS: 1
ALPHA_TNF_PRODUCTION: 1
ALPHA_1_PRODUCTION: 1
ALPHA_6_PRODUCTION: 1
ALPHA_10_PRODUCTION: 1
K_B_T_MA0: 0.001
TRAUMA_CELL_ACTIVATION_SCALE: 10
S_MR: 80000
D_MO_BLOOD: 0.000240676
D_MR_TIS_LUNG: 1.58253e-5
D_MA_TIS_LUNG: 6.87646e-5
K_MO_SOURCE_ENHANCE: 1.0e-2
K_B_T_NA0: 0.001
S_NR: 2500000
D_NU_BLOOD: 0.001925409
D_NU_TIS_LUNG: 0.000240676
K_NU_SOURCE_ENHANCE: 1.0e-2
S_EPRL: 2.016e10
S_EPRS: 2.016e10
D_EP: 7.91264e-6
GUISCALEIL10: 5000
GUISCALEIL6: 20000
GUISCALETNF: 18000
GUISCALE_DAMAGE: 0
GUISCALEIL1: 100
DAMP_LOAD: 0.001
K_EP_DAMP: 1
X_EP_DAMP: 78049.8
XDAMP_EP: 100
KTNFM: 1.0e7
KTNFN: 1.0e7
D_TNF: 0.040773364
KMTNF: 10
KNTNF: 1.0e-4
K_EP_TNF: 1.0e-7
XMTNF: 10
XNTNF: 10
X_EP_TNF: 20
XTNF_EP: 1.0e-5
XTNFN: 1
XTNFM: 1
K1M: 1.0e5
K1N: 1.0e5
K1EP: 1.0e5
D_1: 0.11552453
KM1: 100
KN1: 1.0e-4
K_EP1: 1.0e-7
X1N: 1
X1M: 1
X1EP: 2
XM1: 0.1
XN1: 0.1
X_EP1: 1.0e-5
K6M: 0.01
K6N: 0.01
K6EP: 5.0e-7
D_6: 0.002888113
KM6: 1.0e-14
KN6: 1.0e-14
K_EP6: 1.0e-10
X_EP6: 500
XM6: 1
XN6: 1
X6EP: 1
S_10: 10
K10M: 1000
K10N: 1000
K10EP: 1000
KM10: 1.0e-6
KN10: 1.0e-6
K_EP10: 1.0e-6
K_BASELINE_IL10: 0.003850818
XEP10: 1.0e-14
XM10: 2.5e-7
XN10: 2.5e-7
KINOSM: 1
KINOSN: 1
KINOSEP: 1
XINOS10: 1
XINOSNO: 1
XENOSPE: 25
D_ENOS: 1.0e-5
D_INOS: 1.0e-5
D_NO: 0.002062938
SOURCE_ENOS: 0.001
K_NO_INOS: 0.1
K_NO_ENOS: 0.1
K_NO_MA: 0.1
K_NO_NA: 0.1
K_NO_EP: 0.1
V_LECF: 500
V_SECF: 5000
RECOVERY_SLOWNESS: 10000
MAX_ISS: 75
K_B_T_MA_L: 0.4
K_B_T_NA_L: 0.4
O2SAT0: 98
VENT_PAR1: 2.5e6
VENT_PAR2: 1.0e-5
VENT_PAR3: 1.0e-4
ML_MIN: 0
PG_PER_MIN_PER_ML_PER_CELLS: 1
ONE_PER_ML: 1
PG_PER_CELLS_PER_MIN: 1
UNIT_ML: 1
ONE_PER_MIN: 0
K_COAG_FACTOR_ACTIVATION_IL6: 1.0e-7
KM_COAG: 1.0e-4
XM_COAG: 1.0e-5
KN_COAG: 1
XN_COAG: 1.0e-9
K_EP_COAG: 1.0e-4
X_EP_COAG: 1.0e-5
K_DAMAGE_IL6: 1.25
X_DAMAGE_IL6: 90
IL6_DAMAGE_THRESHOLD: 10
USE_BLOOD_IL6_ONLY: 1
K_DAMAGE_O2SAT: 2.5
O2SAT_DAMAGE_THRESHOLD: 93
MAX_O2SAT: 98
K_DAMAGE_BP: 2.5
X_DAMAGE_BP: 37
BP_DAMAGE_THRESHOLD: 70
K_DAMAGE_TRAUMA: 3.75
DAMAGE_DEATH_THRESHOLD: 276.53
INFUSION_SETTINGS:
MIN_PLASMA_DOSE: 100
MIN_FLUID_DOSE: 100
MIN_RBC_DOSE: 100
MIN_PLATELET_DOSE: 100
TON_PLASMA_INFUSION1: 0
T_PLASMA_INFUSION_DURATION1: 0
PLASMA_DOSE1: 0
TON_PLASMA_INFUSION2: 0
T_PLASMA_INFUSION_DURATION2: 0
PLASMA_DOSE2: 0
TON_PLASMA_INFUSION3: 0
T_PLASMA_INFUSION_DURATION3: 0
PLASMA_DOSE3: 0
TON_PLASMA_INFUSION4: 0
T_PLASMA_INFUSION_DURATION4: 0
PLASMA_DOSE4: 0
TON_PLASMA_INFUSION5: 0
T_PLASMA_INFUSION_DURATION5: 0
PLASMA_DOSE5: 0
TON_PLASMA_INFUSION6: 0
T_PLASMA_INFUSION_DURATION6: 0
PLASMA_DOSE6: 0
TON_PLASMA_INFUSION7: 0
T_PLASMA_INFUSION_DURATION7: 0
PLASMA_DOSE7: 0
TON_PLASMA_INFUSION8: 0
T_PLASMA_INFUSION_DURATION8: 0
PLASMA_DOSE8: 0
TON_PLASMA_INFUSION9: 0
T_PLASMA_INFUSION_DURATION9: 0
PLASMA_DOSE9: 0
TON_PLASMA_INFUSION10: 0
T_PLASMA_INFUSION_DURATION10: 0
PLASMA_DOSE10: 0
TON_FLUID_INFUSION1: 0
T_FLUID_INFUSION_DURATION1: 0
FLUID_DOSE1: 0
TON_FLUID_INFUSION2: 0
T_FLUID_INFUSION_DURATION2: 0
FLUID_DOSE2: 0
TON_FLUID_INFUSION3: 0
T_FLUID_INFUSION_DURATION3: 0
FLUID_DOSE3: 0
TON_FLUID_INFUSION4: 0
T_FLUID_INFUSION_DURATION4: 0
FLUID_DOSE4: 0
TON_FLUID_INFUSION5: 0
T_FLUID_INFUSION_DURATION5: 0
FLUID_DOSE5: 0
TON_FLUID_INFUSION6: 0
T_FLUID_INFUSION_DURATION6: 0
FLUID_DOSE6: 0
TON_FLUID_INFUSION7: 0
T_FLUID_INFUSION_DURATION7: 0
FLUID_DOSE7: 0
TON_FLUID_INFUSION8: 0
T_FLUID_INFUSION_DURATION8: 0
FLUID_DOSE8: 0
TON_FLUID_INFUSION9: 0
T_FLUID_INFUSION_DURATION9: 0
FLUID_DOSE9: 0
TON_FLUID_INFUSION10: 0
T_FLUID_INFUSION_DURATION10: 0
FLUID_DOSE10: 0
TON_RBC_INFUSION1: 0
T_RBC_INFUSION_DURATION1: 0
RBC_DOSE1: 0
TON_RBC_INFUSION2: 0
T_RBC_INFUSION_DURATION2: 0
RBC_DOSE2: 0
TON_RBC_INFUSION3: 0
T_RBC_INFUSION_DURATION3: 0
RBC_DOSE3: 0
TON_RBC_INFUSION4: 0
T_RBC_INFUSION_DURATION4: 0
RBC_DOSE4: 0
TON_RBC_INFUSION5: 0
T_RBC_INFUSION_DURATION5: 0
RBC_DOSE5: 0
TON_RBC_INFUSION6: 0
T_RBC_INFUSION_DURATION6: 0
RBC_DOSE6: 0
TON_RBC_INFUSION7: 0
T_RBC_INFUSION_DURATION7: 0
RBC_DOSE7: 0
TON_RBC_INFUSION8: 0
T_RBC_INFUSION_DURATION8: 0
RBC_DOSE8: 0
TON_RBC_INFUSION9: 0
T_RBC_INFUSION_DURATION9: 0
RBC_DOSE9: 0
TON_RBC_INFUSION10: 0
T_RBC_INFUSION_DURATION10: 0
RBC_DOSE10: 0
TON_PLATELET_INFUSION1: 0
T_PLATELET_INFUSION_DURATION1: 0
PLATELET_DOSE1: 0
TON_PLATELET_INFUSION2: 0
T_PLATELET_INFUSION_DURATION2: 0
PLATELET_DOSE2: 0
TON_PLATELET_INFUSION3: 0
T_PLATELET_INFUSION_DURATION3: 0
PLATELET_DOSE3: 0
TON_PLATELET_INFUSION4: 0
T_PLATELET_INFUSION_DURATION4: 0
PLATELET_DOSE4: 0
TON_PLATELET_INFUSION5: 0
T_PLATELET_INFUSION_DURATION5: 0
PLATELET_DOSE5: 0
TON_PLATELET_INFUSION6: 0
T_PLATELET_INFUSION_DURATION6: 0
PLATELET_DOSE6: 0
TON_PLATELET_INFUSION7: 0
T_PLATELET_INFUSION_DURATION7: 0
PLATELET_DOSE7: 0
TON_PLATELET_INFUSION8: 0
T_PLATELET_INFUSION_DURATION8: 0
PLATELET_DOSE8: 0
TON_PLATELET_INFUSION9: 0
T_PLATELET_INFUSION_DURATION9: 0
PLATELET_DOSE9: 0
TON_PLATELET_INFUSION10: 0
T_PLATELET_INFUSION_DURATION10: 0
PLATELET_DOSE10: 0