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1f8t.pdb
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1f8t.pdb
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HEADER IMMUNE SYSTEM 05-JUL-00 1F8T
TITLE FAB (LNKB-2) OF MONOCLONAL ANTIBODY, CRYSTAL STRUCTURE
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: ANTIBODY FAB FRAGMENT (LIGHT CHAIN);
COMPND 3 CHAIN: L;
COMPND 4 MOL_ID: 2;
COMPND 5 MOLECULE: ANTIBODY FAB FRAGMENT (HEAVY CHAIN);
COMPND 6 CHAIN: H
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS;
SOURCE 3 ORGANISM_COMMON: HOUSE MOUSE;
SOURCE 4 ORGANISM_TAXID: 10090;
SOURCE 5 MOL_ID: 2;
SOURCE 6 ORGANISM_SCIENTIFIC: MUS MUSCULUS;
SOURCE 7 ORGANISM_COMMON: HOUSE MOUSE;
SOURCE 8 ORGANISM_TAXID: 10090
KEYWDS MONOCLONAL ANTIBODY, ANTIGEN-BINDING FRAGMENT, INTERLEUKIN-
KEYWDS 2 2, X-RAY ANALYSIS, CRYSTAL, IMMUNE SYSTEM
EXPDTA X-RAY DIFFRACTION
AUTHOR A.V.FOKIN,P.V.AFONIN,I.I.MIKHAILOVA,I.N.TSYGANNIK,
AUTHOR 2 T.I.MAREEVA
REVDAT 3 24-FEB-09 1F8T 1 VERSN
REVDAT 2 01-APR-03 1F8T 1 JRNL
REVDAT 1 05-JUL-01 1F8T 0
JRNL AUTH A.V.FOKIN,P.V.AFONIN,I.I.U.MIKHAILOVA,
JRNL AUTH 2 I.N.TSYGANNIK,T.I.U.MAREEVA,V.A.NESMEIANOV,
JRNL AUTH 3 W.PANGBORN,N.LEE,W.DUAX,E.SISZAK,V.Z.PLETNEV
JRNL TITL SPATIAL STRUCTURE OF A FAB-FRAGMENT OF A
JRNL TITL 2 MONOCLONAL ANTIBODY TO HUMAN INTERLEUKIN-2 IN TWO
JRNL TITL 3 CRYSTALLINE FORMS AT A RESOLUTION OF 2.2 AND 2.9
JRNL TITL 4 ANGSTROMS
JRNL REF BIOORG.KHIM. V. 26 571 2000
JRNL REFN ISSN 0132-3423
JRNL PMID 11040993
REMARK 1
REMARK 2
REMARK 2 RESOLUTION. 2.20 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 PROGRAM : CNS 0.9
REMARK 3 AUTHORS : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE-
REMARK 3 : KUNSTLEVE,JIANG,KUSZEWSKI,NILGES, PANNU,
REMARK 3 : READ,RICE,SIMONSON,WARREN
REMARK 3
REMARK 3 REFINEMENT TARGET : ENGH & HUBER
REMARK 3
REMARK 3 DATA USED IN REFINEMENT.
REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.20
REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 99.00
REMARK 3 DATA CUTOFF (SIGMA(F)) : 2.000
REMARK 3 DATA CUTOFF HIGH (ABS(F)) : NULL
REMARK 3 DATA CUTOFF LOW (ABS(F)) : NULL
REMARK 3 COMPLETENESS (WORKING+TEST) (%) : 95.0
REMARK 3 NUMBER OF REFLECTIONS : 22492
REMARK 3
REMARK 3 FIT TO DATA USED IN REFINEMENT.
REMARK 3 CROSS-VALIDATION METHOD : NULL
REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM
REMARK 3 R VALUE (WORKING SET) : 0.171
REMARK 3 FREE R VALUE : 0.221
REMARK 3 FREE R VALUE TEST SET SIZE (%) : NULL
REMARK 3 FREE R VALUE TEST SET COUNT : 2116
REMARK 3 ESTIMATED ERROR OF FREE R VALUE : NULL
REMARK 3
REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN.
REMARK 3 TOTAL NUMBER OF BINS USED : NULL
REMARK 3 BIN RESOLUTION RANGE HIGH (A) : NULL
REMARK 3 BIN RESOLUTION RANGE LOW (A) : NULL
REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : NULL
REMARK 3 REFLECTIONS IN BIN (WORKING SET) : NULL
REMARK 3 BIN R VALUE (WORKING SET) : NULL
REMARK 3 BIN FREE R VALUE : NULL
REMARK 3 BIN FREE R VALUE TEST SET SIZE (%) : NULL
REMARK 3 BIN FREE R VALUE TEST SET COUNT : NULL
REMARK 3 ESTIMATED ERROR OF BIN FREE R VALUE : NULL
REMARK 3
REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.
REMARK 3 PROTEIN ATOMS : 3380
REMARK 3 NUCLEIC ACID ATOMS : 0
REMARK 3 HETEROGEN ATOMS : 0
REMARK 3 SOLVENT ATOMS : 213
REMARK 3
REMARK 3 B VALUES.
REMARK 3 FROM WILSON PLOT (A**2) : NULL
REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL
REMARK 3 OVERALL ANISOTROPIC B VALUE.
REMARK 3 B11 (A**2) : NULL
REMARK 3 B22 (A**2) : NULL
REMARK 3 B33 (A**2) : NULL
REMARK 3 B12 (A**2) : NULL
REMARK 3 B13 (A**2) : NULL
REMARK 3 B23 (A**2) : NULL
REMARK 3
REMARK 3 ESTIMATED COORDINATE ERROR.
REMARK 3 ESD FROM LUZZATI PLOT (A) : NULL
REMARK 3 ESD FROM SIGMAA (A) : NULL
REMARK 3 LOW RESOLUTION CUTOFF (A) : NULL
REMARK 3
REMARK 3 CROSS-VALIDATED ESTIMATED COORDINATE ERROR.
REMARK 3 ESD FROM C-V LUZZATI PLOT (A) : NULL
REMARK 3 ESD FROM C-V SIGMAA (A) : NULL
REMARK 3
REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES.
REMARK 3 BOND LENGTHS (A) : 0.006
REMARK 3 BOND ANGLES (DEGREES) : 1.33
REMARK 3 DIHEDRAL ANGLES (DEGREES) : 27.30
REMARK 3 IMPROPER ANGLES (DEGREES) : 0.84
REMARK 3
REMARK 3 ISOTROPIC THERMAL MODEL : NULL
REMARK 3
REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. RMS SIGMA
REMARK 3 MAIN-CHAIN BOND (A**2) : NULL ; NULL
REMARK 3 MAIN-CHAIN ANGLE (A**2) : NULL ; NULL
REMARK 3 SIDE-CHAIN BOND (A**2) : NULL ; NULL
REMARK 3 SIDE-CHAIN ANGLE (A**2) : NULL ; NULL
REMARK 3
REMARK 3 BULK SOLVENT MODELING.
REMARK 3 METHOD USED : NULL
REMARK 3 KSOL : NULL
REMARK 3 BSOL : NULL
REMARK 3
REMARK 3 NCS MODEL : NULL
REMARK 3
REMARK 3 NCS RESTRAINTS. RMS SIGMA/WEIGHT
REMARK 3 GROUP 1 POSITIONAL (A) : NULL ; NULL
REMARK 3 GROUP 1 B-FACTOR (A**2) : NULL ; NULL
REMARK 3
REMARK 3 PARAMETER FILE 1 : NULL
REMARK 3 TOPOLOGY FILE 1 : NULL
REMARK 3
REMARK 3 OTHER REFINEMENT REMARKS: CROSS-VALIDATED MAXIMUM LIKELIHOOD
REMARK 3 SIMULATED ANNEALING REFINEMENT (CNS PACKAGE)
REMARK 4
REMARK 4 1F8T COMPLIES WITH FORMAT V. 3.15, 01-DEC-08
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 06-JUL-00.
REMARK 100 THE RCSB ID CODE IS RCSB011384.
REMARK 200
REMARK 200 EXPERIMENTAL DETAILS
REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION
REMARK 200 DATE OF DATA COLLECTION : 22-FEB-99
REMARK 200 TEMPERATURE (KELVIN) : 300.0
REMARK 200 PH : 5.6
REMARK 200 NUMBER OF CRYSTALS USED : 1
REMARK 200
REMARK 200 SYNCHROTRON (Y/N) : N
REMARK 200 RADIATION SOURCE : ROTATING ANODE
REMARK 200 BEAMLINE : NULL
REMARK 200 X-RAY GENERATOR MODEL : RIGAKU RU200HB
REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M
REMARK 200 WAVELENGTH OR RANGE (A) : 1.5418
REMARK 200 MONOCHROMATOR : NULL
REMARK 200 OPTICS : NULL
REMARK 200
REMARK 200 DETECTOR TYPE : IMAGE PLATE
REMARK 200 DETECTOR MANUFACTURER : RIGAKU RAXIS IIC
REMARK 200 INTENSITY-INTEGRATION SOFTWARE : DENZO
REMARK 200 DATA SCALING SOFTWARE : SCALEPACK
REMARK 200
REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 21459
REMARK 200 RESOLUTION RANGE HIGH (A) : 2.200
REMARK 200 RESOLUTION RANGE LOW (A) : 99.000
REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL
REMARK 200
REMARK 200 OVERALL.
REMARK 200 COMPLETENESS FOR RANGE (%) : 90.6
REMARK 200 DATA REDUNDANCY : 5.700
REMARK 200 R MERGE (I) : 0.04800
REMARK 200 R SYM (I) : NULL
REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 24.2000
REMARK 200
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.
REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.20
REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.31
REMARK 200 COMPLETENESS FOR SHELL (%) : 94.2
REMARK 200 DATA REDUNDANCY IN SHELL : 2.80
REMARK 200 R MERGE FOR SHELL (I) : 0.19350
REMARK 200 R SYM FOR SHELL (I) : NULL
REMARK 200 <I/SIGMA(I)> FOR SHELL : NULL
REMARK 200
REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: NULL
REMARK 200 SOFTWARE USED: X-PLOR
REMARK 200 STARTING MODEL: NULL
REMARK 200
REMARK 200 REMARK: NULL
REMARK 280
REMARK 280 CRYSTAL
REMARK 280 SOLVENT CONTENT, VS (%): 47.72
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.35
REMARK 280
REMARK 280 CRYSTALLIZATION CONDITIONS: PEG-4000, 2-PROPANOL, NA-CITRATE,
REMARK 280 PH 5.6, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 300.0K
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 21 21 21
REMARK 290
REMARK 290 SYMOP SYMMETRY
REMARK 290 NNNMMM OPERATOR
REMARK 290 1555 X,Y,Z
REMARK 290 2555 -X+1/2,-Y,Z+1/2
REMARK 290 3555 -X,Y+1/2,-Z+1/2
REMARK 290 4555 X+1/2,-Y+1/2,-Z
REMARK 290
REMARK 290 WHERE NNN -> OPERATOR NUMBER
REMARK 290 MMM -> TRANSLATION VECTOR
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY
REMARK 290 RELATED MOLECULES.
REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000
REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000
REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000
REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 36.12000
REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000
REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 43.49500
REMARK 290 SMTRY1 3 -1.000000 0.000000 0.000000 0.00000
REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 36.00500
REMARK 290 SMTRY3 3 0.000000 0.000000 -1.000000 43.49500
REMARK 290 SMTRY1 4 1.000000 0.000000 0.000000 36.12000
REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 36.00500
REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000
REMARK 290
REMARK 290 REMARK: NULL
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC
REMARK 350 SOFTWARE USED: PISA
REMARK 350 TOTAL BURIED SURFACE AREA: 3910 ANGSTROM**2
REMARK 350 SURFACE AREA OF THE COMPLEX: 19780 ANGSTROM**2
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -24.0 KCAL/MOL
REMARK 350 APPLY THE FOLLOWING TO CHAINS: L, H
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3
REMARK 500 CYS H 92 CA - CB - SG ANGL. DEV. = 7.8 DEGREES
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 VAL L 51 -47.44 73.11
REMARK 500 SER L 67 149.90 -171.13
REMARK 500 ASN L 212 -43.33 -146.22
REMARK 500 SER H 15 -13.07 80.55
REMARK 500 TYR H 33 170.62 72.33
REMARK 500 ASN H 43 -11.38 83.93
REMARK 500 LYS H 64 -43.23 -23.39
REMARK 500 ASP H 97 -15.19 77.73
REMARK 500 SER H 128 57.73 -64.00
REMARK 500 GLN H 133 80.82 64.33
REMARK 500 ASN H 135 -162.34 -69.30
REMARK 500 PHE H 148 136.72 -170.04
REMARK 500 GLN H 179 114.40 -162.09
REMARK 500 SER H 180 37.29 70.92
REMARK 500 PRO H 199 -106.98 -54.42
REMARK 500 SER H 203 -74.27 -57.76
REMARK 500 ASP H 229 -75.96 -109.57
REMARK 500
REMARK 500 REMARK: NULL
DBREF 1F8T L 1 214 PDB 1F8T 1F8T 1 214
DBREF 1F8T H 1 230 PDB 1F8T 1F8T 1 230
SEQRES 1 L 219 ASP VAL GLN MET THR GLN THR PRO LEU THR LEU SER VAL
SEQRES 2 L 219 THR ILE GLY GLN PRO ALA SER ILE SER CYS GLU SER SER
SEQRES 3 L 219 GLN SER LEU LEU TYR SER ASN GLY LYS THR TYR LEU ASN
SEQRES 4 L 219 TRP LEU LEU GLN ARG PRO GLY GLN SER PRO LYS ARG LEU
SEQRES 5 L 219 ILE TYR LEU VAL SER LYS LEU ASP SER GLY VAL PRO ASP
SEQRES 6 L 219 ARG PHE THR GLY SER GLY SER GLY THR ASP PHE THR LEU
SEQRES 7 L 219 ARG ILE SER ARG VAL GLU ALA GLU ASP LEU GLY VAL TYR
SEQRES 8 L 219 TYR CYS VAL GLN GLY THR HIS PHE PRO ARG THR PHE GLY
SEQRES 9 L 219 GLY GLY THR LYS LEU GLU ILE LYS ARG ALA ASP ALA ALA
SEQRES 10 L 219 PRO THR VAL SER ILE PHE PRO PRO SER SER GLU GLN LEU
SEQRES 11 L 219 THR SER GLY GLY ALA SER VAL VAL CYS PHE LEU ASN ASN
SEQRES 12 L 219 PHE TYR PRO LYS ASP ILE ASN VAL LYS TRP LYS ILE ASP
SEQRES 13 L 219 GLY SER GLU ARG GLN ASN GLY VAL LEU ASN SER TRP THR
SEQRES 14 L 219 ASP GLN ASP SER LYS ASP SER THR TYR SER MET SER SER
SEQRES 15 L 219 THR LEU THR LEU THR LYS ASP GLU TYR GLU ARG HIS ASN
SEQRES 16 L 219 SER TYR THR CYS GLU ALA THR HIS LYS THR SER THR SER
SEQRES 17 L 219 PRO ILE VAL LYS SER PHE ASN ARG ASN GLU CYS
SEQRES 1 H 220 GLY VAL GLN LEU GLN GLU SER GLY PRO GLY LEU VAL LYS
SEQRES 2 H 220 PRO SER GLN SER LEU SER LEU THR CYS THR VAL THR GLY
SEQRES 3 H 220 TYR SER ILE THR SER ASP TYR ALA TRP ASN TRP ILE ARG
SEQRES 4 H 220 GLN PHE PRO GLY ASN LYS LEU GLU TRP MET GLY TYR ILE
SEQRES 5 H 220 THR TYR SER GLY SER THR GLY TYR ASN PRO SER LEU LYS
SEQRES 6 H 220 SER ARG ILE SER ILE THR ARG ASP THR SER LYS ASN GLN
SEQRES 7 H 220 PHE PHE LEU GLN LEU ASN SER VAL THR THR GLU ASP THR
SEQRES 8 H 220 ALA THR TYR TYR CYS ALA SER TYR ASP ASP TYR THR TRP
SEQRES 9 H 220 PHE THR TYR TRP GLY GLN GLY THR LEU VAL THR VAL SER
SEQRES 10 H 220 ALA ALA LYS THR THR PRO PRO SER VAL PHE PRO LEU ALA
SEQRES 11 H 220 PRO GLY SER ALA ALA GLN THR ASN SER MET VAL THR LEU
SEQRES 12 H 220 GLY CYS LEU VAL LYS GLY TYR PHE PRO GLU PRO VAL THR
SEQRES 13 H 220 VAL THR TRP ASN SER GLY SER LEU SER SER GLY VAL HIS
SEQRES 14 H 220 THR PHE PRO ALA VAL LEU GLN SER ASP LEU TYR THR LEU
SEQRES 15 H 220 SER SER SER VAL THR VAL PRO SER SER PRO ARG PRO SER
SEQRES 16 H 220 GLU THR VAL THR CYS ASN VAL ALA HIS PRO ALA SER SER
SEQRES 17 H 220 THR LYS VAL ASP LYS LYS ILE VAL PRO ARG ASP CYS
FORMUL 3 HOH *213(H2 O)
HELIX 1 1 GLU L 79 LEU L 83 5 5
HELIX 2 2 SER L 121 SER L 127 1 7
HELIX 3 3 LYS L 183 GLU L 187 1 5
HELIX 4 4 THR H 83 THR H 87 5 5
HELIX 5 5 SER H 163 SER H 165 5 3
HELIX 6 6 PRO H 213 SER H 216 5 4
SHEET 1 A 4 MET L 4 THR L 7 0
SHEET 2 A 4 ALA L 19 SER L 25 -1 N SER L 22 O THR L 7
SHEET 3 A 4 ASP L 70 ILE L 75 -1 O PHE L 71 N CYS L 23
SHEET 4 A 4 PHE L 62 SER L 67 -1 O THR L 63 N ARG L 74
SHEET 1 B 5 LYS L 53 LEU L 54 0
SHEET 2 B 5 LYS L 45 TYR L 49 -1 N TYR L 49 O LYS L 53
SHEET 3 B 5 LEU L 33 GLN L 38 -1 O TRP L 35 N LEU L 47
SHEET 4 B 5 GLY L 84 GLN L 90 -1 O VAL L 85 N GLN L 38
SHEET 5 B 5 THR L 97 PHE L 98 -1 O THR L 97 N GLN L 90
SHEET 1 C 6 LYS L 53 LEU L 54 0
SHEET 2 C 6 LYS L 45 TYR L 49 -1 N TYR L 49 O LYS L 53
SHEET 3 C 6 LEU L 33 GLN L 38 -1 O TRP L 35 N LEU L 47
SHEET 4 C 6 GLY L 84 GLN L 90 -1 O VAL L 85 N GLN L 38
SHEET 5 C 6 THR L 102 ILE L 106 -1 O THR L 102 N TYR L 86
SHEET 6 C 6 THR L 10 VAL L 13 1 O LEU L 11 N GLU L 105
SHEET 1 D 4 THR L 114 PHE L 118 0
SHEET 2 D 4 GLY L 129 PHE L 139 -1 O VAL L 133 N PHE L 118
SHEET 3 D 4 TYR L 173 THR L 182 -1 O TYR L 173 N PHE L 139
SHEET 4 D 4 VAL L 159 TRP L 163 -1 N LEU L 160 O THR L 178
SHEET 1 E 4 SER L 153 ARG L 155 0
SHEET 2 E 4 ASN L 145 ILE L 150 -1 O TRP L 148 N ARG L 155
SHEET 3 E 4 SER L 191 THR L 197 -1 N THR L 193 O LYS L 149
SHEET 4 E 4 ILE L 205 ASN L 210 -1 O ILE L 205 N ALA L 196
SHEET 1 F 4 GLN H 3 SER H 7 0
SHEET 2 F 4 LEU H 18 THR H 25 -1 N THR H 21 O SER H 7
SHEET 3 F 4 GLN H 77 LEU H 82 -1 O PHE H 78 N CYS H 22
SHEET 4 F 4 ILE H 67 ASP H 72 -1 O SER H 68 N GLN H 81
SHEET 1 G 5 THR H 57 TYR H 59 0
SHEET 2 G 5 LEU H 45 THR H 52 -1 N TYR H 50 O GLY H 58
SHEET 3 G 5 ALA H 34 GLN H 39 -1 N TRP H 35 O ILE H 51
SHEET 4 G 5 ALA H 88 TYR H 95 -1 O THR H 89 N GLN H 39
SHEET 5 G 5 THR H 101 TRP H 103 -1 O TYR H 102 N SER H 94
SHEET 1 H 6 THR H 57 TYR H 59 0
SHEET 2 H 6 LEU H 45 THR H 52 -1 N TYR H 50 O GLY H 58
SHEET 3 H 6 ALA H 34 GLN H 39 -1 N TRP H 35 O ILE H 51
SHEET 4 H 6 ALA H 88 TYR H 95 -1 O THR H 89 N GLN H 39
SHEET 5 H 6 THR H 107 VAL H 111 -1 O THR H 107 N TYR H 90
SHEET 6 H 6 LEU H 11 VAL H 12 1 N VAL H 12 O THR H 110
SHEET 1 I 4 SER H 120 LEU H 124 0
SHEET 2 I 4 MET H 137 TYR H 147 -1 O GLY H 141 N LEU H 124
SHEET 3 I 4 TYR H 185 PRO H 194 -1 N TYR H 185 O TYR H 147
SHEET 4 I 4 VAL H 171 THR H 173 -1 N HIS H 172 O SER H 190
SHEET 1 J 4 SER H 120 LEU H 124 0
SHEET 2 J 4 MET H 137 TYR H 147 -1 O GLY H 141 N LEU H 124
SHEET 3 J 4 TYR H 185 PRO H 194 -1 N TYR H 185 O TYR H 147
SHEET 4 J 4 VAL H 177 LEU H 178 -1 N VAL H 177 O THR H 186
SHEET 1 K 3 THR H 153 TRP H 157 0
SHEET 2 K 3 THR H 207 HIS H 212 -1 N ASN H 209 O THR H 156
SHEET 3 K 3 THR H 217 LYS H 222 -1 O THR H 217 N HIS H 212
SSBOND 1 CYS L 23 CYS L 88 1555 1555 2.02
SSBOND 2 CYS L 134 CYS L 194 1555 1555 2.03
SSBOND 3 CYS L 214 CYS H 230 1555 1555 2.03
SSBOND 4 CYS H 22 CYS H 92 1555 1555 2.04
SSBOND 5 CYS H 142 CYS H 208 1555 1555 2.03
CISPEP 1 THR L 7 PRO L 8 0 -0.17
CISPEP 2 PHE L 94 PRO L 95 0 0.01
CISPEP 3 TYR L 140 PRO L 141 0 0.02
CISPEP 4 PHE H 148 PRO H 149 0 -0.34
CISPEP 5 GLU H 150 PRO H 151 0 0.19
CISPEP 6 ARG H 200 PRO H 202 0 -0.03
CRYST1 72.240 72.010 86.990 90.00 90.00 90.00 P 21 21 21 4
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 0.013843 0.000000 0.000000 0.00000
SCALE2 0.000000 0.013887 0.000000 0.00000
SCALE3 0.000000 0.000000 0.011496 0.00000
ATOM 1 N ASP L 1 49.347 -62.804 60.380 1.00 34.60 N
ATOM 2 CA ASP L 1 47.975 -63.194 59.946 1.00 33.86 C
ATOM 3 C ASP L 1 47.122 -63.665 61.114 1.00 34.02 C
ATOM 4 O ASP L 1 47.573 -64.451 61.947 1.00 32.23 O
ATOM 5 CB ASP L 1 48.056 -64.305 58.901 1.00 33.99 C
ATOM 6 CG ASP L 1 48.443 -63.789 57.533 1.00 36.93 C
ATOM 7 OD1 ASP L 1 49.288 -62.872 57.462 1.00 36.67 O
ATOM 8 OD2 ASP L 1 47.906 -64.309 56.529 1.00 38.81 O
ATOM 9 N VAL L 2 45.889 -63.176 61.175 1.00 31.94 N
ATOM 10 CA VAL L 2 44.978 -63.576 62.233 1.00 29.81 C
ATOM 11 C VAL L 2 44.472 -64.973 61.900 1.00 28.28 C
ATOM 12 O VAL L 2 43.989 -65.221 60.796 1.00 27.24 O
ATOM 13 CB VAL L 2 43.787 -62.613 62.341 1.00 30.66 C
ATOM 14 CG1 VAL L 2 42.813 -63.100 63.405 1.00 29.42 C
ATOM 15 CG2 VAL L 2 44.287 -61.226 62.680 1.00 31.43 C
ATOM 16 N GLN L 3 44.585 -65.878 62.864 1.00 25.93 N
ATOM 17 CA GLN L 3 44.166 -67.262 62.686 1.00 24.46 C
ATOM 18 C GLN L 3 42.730 -67.505 63.153 1.00 23.33 C
ATOM 19 O GLN L 3 42.389 -67.234 64.302 1.00 20.10 O
ATOM 20 CB GLN L 3 45.127 -68.170 63.455 1.00 29.74 C
ATOM 21 CG GLN L 3 44.676 -69.611 63.591 1.00 39.72 C
ATOM 22 CD GLN L 3 45.288 -70.292 64.807 1.00 51.31 C
ATOM 23 OE1 GLN L 3 45.022 -71.468 65.079 1.00 57.11 O
ATOM 24 NE2 GLN L 3 46.111 -69.551 65.550 1.00 54.00 N
ATOM 25 N MET L 4 41.894 -68.026 62.256 1.00 24.27 N
ATOM 26 CA MET L 4 40.497 -68.318 62.576 1.00 22.89 C
ATOM 27 C MET L 4 40.326 -69.824 62.795 1.00 21.48 C
ATOM 28 O MET L 4 40.633 -70.625 61.911 1.00 23.73 O
ATOM 29 CB MET L 4 39.580 -67.844 61.439 1.00 22.77 C
ATOM 30 CG MET L 4 39.703 -66.353 61.088 1.00 20.45 C
ATOM 31 SD MET L 4 39.237 -65.204 62.430 1.00 23.95 S
ATOM 32 CE MET L 4 37.476 -65.310 62.370 1.00 24.76 C
ATOM 33 N THR L 5 39.836 -70.208 63.971 1.00 20.55 N
ATOM 34 CA THR L 5 39.652 -71.626 64.301 1.00 20.64 C
ATOM 35 C THR L 5 38.188 -72.004 64.496 1.00 20.08 C
ATOM 36 O THR L 5 37.534 -71.507 65.409 1.00 20.87 O
ATOM 37 CB THR L 5 40.411 -71.996 65.590 1.00 23.39 C
ATOM 38 OG1 THR L 5 41.784 -71.608 65.465 1.00 30.91 O
ATOM 39 CG2 THR L 5 40.342 -73.494 65.840 1.00 26.97 C
ATOM 40 N GLN L 6 37.680 -72.891 63.643 1.00 21.97 N
ATOM 41 CA GLN L 6 36.288 -73.325 63.743 1.00 25.11 C
ATOM 42 C GLN L 6 36.147 -74.705 64.370 1.00 25.56 C
ATOM 43 O GLN L 6 36.912 -75.622 64.064 1.00 26.32 O
ATOM 44 CB GLN L 6 35.619 -73.361 62.367 1.00 20.36 C
ATOM 45 CG GLN L 6 35.642 -72.065 61.613 1.00 21.68 C
ATOM 46 CD GLN L 6 34.790 -72.117 60.369 1.00 20.77 C
ATOM 47 OE1 GLN L 6 35.059 -71.412 59.397 1.00 24.00 O
ATOM 48 NE2 GLN L 6 33.743 -72.948 60.392 1.00 16.25 N
ATOM 49 N THR L 7 35.141 -74.839 65.229 1.00 27.28 N
ATOM 50 CA THR L 7 34.842 -76.087 65.919 1.00 29.94 C
ATOM 51 C THR L 7 33.332 -76.282 65.861 1.00 30.28 C
ATOM 52 O THR L 7 32.576 -75.339 66.091 1.00 30.65 O
ATOM 53 CB THR L 7 35.254 -76.017 67.400 1.00 33.05 C
ATOM 54 OG1 THR L 7 36.599 -75.536 67.500 1.00 36.48 O
ATOM 55 CG2 THR L 7 35.171 -77.398 68.042 1.00 38.31 C
ATOM 56 N PRO L 8 32.867 -77.502 65.555 1.00 29.43 N
ATOM 57 CA PRO L 8 33.636 -78.711 65.256 1.00 27.63 C
ATOM 58 C PRO L 8 33.982 -78.790 63.773 1.00 27.58 C
ATOM 59 O PRO L 8 33.634 -77.895 63.000 1.00 28.53 O
ATOM 60 CB PRO L 8 32.688 -79.819 65.682 1.00 27.24 C
ATOM 61 CG PRO L 8 31.369 -79.273 65.234 1.00 29.03 C
ATOM 62 CD PRO L 8 31.432 -77.819 65.677 1.00 28.99 C
ATOM 63 N LEU L 9 34.669 -79.856 63.373 1.00 27.41 N
ATOM 64 CA LEU L 9 35.035 -80.024 61.969 1.00 25.92 C
ATOM 65 C LEU L 9 33.808 -80.409 61.159 1.00 23.43 C
ATOM 66 O LEU L 9 33.602 -79.903 60.059 1.00 22.17 O
ATOM 67 CB LEU L 9 36.112 -81.101 61.803 1.00 26.82 C
ATOM 68 CG LEU L 9 37.495 -80.783 62.368 1.00 33.53 C
ATOM 69 CD1 LEU L 9 38.436 -81.939 62.074 1.00 35.06 C
ATOM 70 CD2 LEU L 9 38.024 -79.497 61.750 1.00 36.76 C
ATOM 71 N THR L 10 33.003 -81.313 61.708 1.00 20.90 N
ATOM 72 CA THR L 10 31.786 -81.765 61.045 1.00 23.73 C
ATOM 73 C THR L 10 30.657 -81.823 62.063 1.00 25.10 C
ATOM 74 O THR L 10 30.892 -81.949 63.267 1.00 24.48 O
ATOM 75 CB THR L 10 31.952 -83.162 60.410 1.00 23.27 C
ATOM 76 OG1 THR L 10 32.247 -84.122 61.430 1.00 30.08 O
ATOM 77 CG2 THR L 10 33.068 -83.152 59.391 1.00 27.84 C
ATOM 78 N LEU L 11 29.429 -81.735 61.573 1.00 26.12 N
ATOM 79 CA LEU L 11 28.270 -81.748 62.444 1.00 30.70 C
ATOM 80 C LEU L 11 27.128 -82.507 61.785 1.00 32.76 C
ATOM 81 O LEU L 11 26.587 -82.068 60.769 1.00 33.60 O
ATOM 82 CB LEU L 11 27.846 -80.305 62.733 1.00 33.97 C
ATOM 83 CG LEU L 11 26.746 -80.010 63.752 1.00 39.69 C
ATOM 84 CD1 LEU L 11 27.192 -80.425 65.147 1.00 43.19 C
ATOM 85 CD2 LEU L 11 26.443 -78.526 63.725 1.00 43.64 C
ATOM 86 N SER L 12 26.772 -83.657 62.352 1.00 31.08 N
ATOM 87 CA SER L 12 25.673 -84.444 61.811 1.00 30.15 C
ATOM 88 C SER L 12 24.455 -84.190 62.693 1.00 29.02 C
ATOM 89 O SER L 12 24.413 -84.618 63.847 1.00 28.74 O
ATOM 90 CB SER L 12 26.029 -85.930 61.799 1.00 32.01 C
ATOM 91 OG SER L 12 25.021 -86.675 61.134 1.00 36.13 O
ATOM 92 N VAL L 13 23.466 -83.492 62.142 1.00 26.21 N
ATOM 93 CA VAL L 13 22.262 -83.142 62.889 1.00 28.30 C
ATOM 94 C VAL L 13 20.979 -83.551 62.180 1.00 28.12 C
ATOM 95 O VAL L 13 20.883 -83.456 60.958 1.00 28.03 O
ATOM 96 CB VAL L 13 22.206 -81.619 63.131 1.00 28.47 C
ATOM 97 CG1 VAL L 13 21.023 -81.274 64.021 1.00 31.69 C
ATOM 98 CG2 VAL L 13 23.507 -81.148 63.752 1.00 29.64 C
ATOM 99 N THR L 14 19.988 -83.988 62.952 1.00 27.89 N
ATOM 100 CA THR L 14 18.711 -84.403 62.378 1.00 28.32 C
ATOM 101 C THR L 14 17.806 -83.194 62.173 1.00 26.52 C
ATOM 102 O THR L 14 17.849 -82.242 62.952 1.00 25.01 O
ATOM 103 CB THR L 14 17.975 -85.404 63.291 1.00 28.53 C
ATOM 104 OG1 THR L 14 17.322 -84.697 64.350 1.00 32.97 O
ATOM 105 CG2 THR L 14 18.955 -86.389 63.893 1.00 29.78 C
ATOM 106 N ILE L 15 16.990 -83.238 61.122 1.00 27.49 N
ATOM 107 CA ILE L 15 16.068 -82.149 60.813 1.00 30.40 C
ATOM 108 C ILE L 15 15.236 -81.785 62.045 1.00 31.66 C
ATOM 109 O ILE L 15 14.739 -82.664 62.748 1.00 30.80 O
ATOM 110 CB ILE L 15 15.103 -82.541 59.667 1.00 33.00 C
ATOM 111 CG1 ILE L 15 15.894 -82.880 58.402 1.00 34.49 C
ATOM 112 CG2 ILE L 15 14.138 -81.397 59.380 1.00 31.76 C
ATOM 113 CD1 ILE L 15 16.671 -81.711 57.840 1.00 35.24 C
ATOM 114 N GLY L 16 15.099 -80.488 62.307 1.00 33.59 N
ATOM 115 CA GLY L 16 14.318 -80.042 63.447 1.00 31.81 C
ATOM 116 C GLY L 16 15.142 -79.797 64.694 1.00 32.58 C
ATOM 117 O GLY L 16 14.702 -79.091 65.603 1.00 30.43 O
ATOM 118 N GLN L 17 16.333 -80.383 64.754 1.00 32.24 N
ATOM 119 CA GLN L 17 17.197 -80.191 65.911 1.00 34.33 C
ATOM 120 C GLN L 17 18.093 -78.971 65.731 1.00 34.70 C
ATOM 121 O GLN L 17 18.320 -78.516 64.608 1.00 32.37 O
ATOM 122 CB GLN L 17 18.045 -81.440 66.156 1.00 37.95 C
ATOM 123 CG GLN L 17 17.245 -82.595 66.730 1.00 45.88 C
ATOM 124 CD GLN L 17 16.597 -82.243 68.062 1.00 49.94 C
ATOM 125 OE1 GLN L 17 17.284 -82.013 69.060 1.00 49.94 O
ATOM 126 NE2 GLN L 17 15.268 -82.189 68.079 1.00 51.10 N
ATOM 127 N PRO L 18 18.596 -78.410 66.845 1.00 33.30 N
ATOM 128 CA PRO L 18 19.467 -77.234 66.790 1.00 32.71 C
ATOM 129 C PRO L 18 20.924 -77.585 66.494 1.00 30.96 C
ATOM 130 O PRO L 18 21.369 -78.705 66.735 1.00 30.74 O
ATOM 131 CB PRO L 18 19.289 -76.622 68.173 1.00 31.82 C
ATOM 132 CG PRO L 18 19.175 -77.838 69.037 1.00 33.36 C
ATOM 133 CD PRO L 18 18.236 -78.728 68.240 1.00 34.01 C
ATOM 134 N ALA L 19 21.657 -76.614 65.963 1.00 28.50 N
ATOM 135 CA ALA L 19 23.064 -76.802 65.641 1.00 27.23 C
ATOM 136 C ALA L 19 23.816 -75.537 66.027 1.00 27.07 C
ATOM 137 O ALA L 19 23.265 -74.434 65.976 1.00 24.32 O
ATOM 138 CB ALA L 19 23.231 -77.079 64.157 1.00 30.04 C
ATOM 139 N SER L 20 25.075 -75.694 66.411 1.00 24.81 N
ATOM 140 CA SER L 20 25.874 -74.549 66.816 1.00 27.97 C
ATOM 141 C SER L 20 27.304 -74.675 66.310 1.00 26.96 C
ATOM 142 O SER L 20 27.912 -75.739 66.408 1.00 27.07 O
ATOM 143 CB SER L 20 25.863 -74.436 68.344 1.00 29.31 C
ATOM 144 OG SER L 20 26.505 -73.254 68.779 1.00 39.96 O
ATOM 145 N ILE L 21 27.835 -73.588 65.757 1.00 26.94 N
ATOM 146 CA ILE L 21 29.202 -73.587 65.246 1.00 26.44 C
ATOM 147 C ILE L 21 29.987 -72.495 65.959 1.00 24.60 C
ATOM 148 O ILE L 21 29.512 -71.372 66.100 1.00 22.55 O
ATOM 149 CB ILE L 21 29.262 -73.294 63.728 1.00 26.88 C
ATOM 150 CG1 ILE L 21 28.182 -74.084 62.980 1.00 25.90 C
ATOM 151 CG2 ILE L 21 30.650 -73.642 63.199 1.00 22.24 C
ATOM 152 CD1 ILE L 21 28.294 -75.573 63.116 1.00 34.36 C
ATOM 153 N SER L 22 31.193 -72.827 66.396 1.00 24.87 N
ATOM 154 CA SER L 22 32.035 -71.873 67.100 1.00 25.53 C
ATOM 155 C SER L 22 33.208 -71.410 66.258 1.00 24.12 C
ATOM 156 O SER L 22 33.753 -72.167 65.452 1.00 20.85 O
ATOM 157 CB SER L 22 32.569 -72.492 68.391 1.00 27.44 C
ATOM 158 OG SER L 22 31.509 -72.778 69.285 1.00 40.03 O
ATOM 159 N CYS L 23 33.601 -70.161 66.458 1.00 22.21 N
ATOM 160 CA CYS L 23 34.723 -69.603 65.733 1.00 24.67 C
ATOM 161 C CYS L 23 35.566 -68.736 66.646 1.00 24.91 C
ATOM 162 O CYS L 23 35.044 -67.852 67.321 1.00 26.77 O
ATOM 163 CB CYS L 23 34.238 -68.768 64.563 1.00 27.61 C
ATOM 164 SG CYS L 23 35.635 -68.171 63.582 1.00 39.58 S
ATOM 165 N GLU L 24 36.873 -68.977 66.651 1.00 26.57 N
ATOM 166 CA GLU L 24 37.777 -68.213 67.502 1.00 28.88 C
ATOM 167 C GLU L 24 38.908 -67.556 66.721 1.00 24.96 C
ATOM 168 O GLU L 24 39.524 -68.172 65.852 1.00 19.29 O
ATOM 169 CB GLU L 24 38.365 -69.125 68.583 1.00 37.33 C
ATOM 170 CG GLU L 24 37.315 -69.756 69.479 1.00 48.95 C
ATOM 171 CD GLU L 24 37.910 -70.705 70.501 1.00 57.09 C
ATOM 172 OE1 GLU L 24 38.532 -71.709 70.088 1.00 62.46 O
ATOM 173 OE2 GLU L 24 37.754 -70.447 71.715 1.00 61.25 O
ATOM 174 N SER L 25 39.178 -66.295 67.036 1.00 23.05 N
ATOM 175 CA SER L 25 40.243 -65.570 66.368 1.00 24.10 C
ATOM 176 C SER L 25 41.380 -65.356 67.350 1.00 23.38 C
ATOM 177 O SER L 25 41.154 -65.200 68.547 1.00 23.77 O
ATOM 178 CB SER L 25 39.729 -64.226 65.850 1.00 23.21 C
ATOM 179 OG SER L 25 39.039 -63.530 66.868 1.00 24.94 O
ATOM 180 N SER L 26 42.602 -65.361 66.833 1.00 23.43 N
ATOM 181 CA SER L 26 43.792 -65.179 67.649 1.00 22.76 C
ATOM 182 C SER L 26 43.921 -63.740 68.152 1.00 25.79 C
ATOM 183 O SER L 26 44.600 -63.476 69.148 1.00 27.95 O
ATOM 184 CB SER L 26 45.023 -65.575 66.834 1.00 23.39 C
ATOM 185 OG SER L 26 45.013 -64.937 65.570 1.00 21.58 O
ATOM 186 N GLN L 27 43.266 -62.813 67.460 1.00 23.64 N
ATOM 187 CA GLN L 27 43.289 -61.405 67.832 1.00 24.84 C
ATOM 188 C GLN L 27 41.869 -60.863 67.858 1.00 25.95 C
ATOM 189 O GLN L 27 40.987 -61.380 67.172 1.00 26.41 O
ATOM 190 CB GLN L 27 44.108 -60.589 66.830 1.00 27.09 C
ATOM 191 CG GLN L 27 45.602 -60.618 67.048 1.00 35.67 C
ATOM 192 CD GLN L 27 46.338 -59.767 66.033 1.00 38.53 C
ATOM 193 OE1 GLN L 27 46.675 -60.228 64.942 1.00 43.32 O
ATOM 194 NE2 GLN L 27 46.572 -58.507 66.380 1.00 40.19 N
ATOM 195 N SER L 27A 41.653 -59.819 68.651 1.00 21.30 N
ATOM 196 CA SER L 27A 40.340 -59.209 68.744 1.00 23.38 C
ATOM 197 C SER L 27A 39.920 -58.676 67.377 1.00 22.05 C
ATOM 198 O SER L 27A 40.712 -58.050 66.678 1.00 19.83 O
ATOM 199 CB SER L 27A 40.362 -58.057 69.745 1.00 20.17 C
ATOM 200 OG SER L 27A 39.122 -57.376 69.738 1.00 24.39 O
ATOM 201 N LEU L 27B 38.669 -58.918 67.003 1.00 21.73 N
ATOM 202 CA LEU L 27B 38.173 -58.446 65.720 1.00 20.41 C
ATOM 203 C LEU L 27B 37.484 -57.089 65.854 1.00 21.13 C
ATOM 204 O LEU L 27B 36.749 -56.670 64.961 1.00 21.34 O
ATOM 205 CB LEU L 27B 37.212 -59.473 65.116 1.00 17.54 C
ATOM 206 CG LEU L 27B 37.805 -60.882 64.938 1.00 21.70 C
ATOM 207 CD1 LEU L 27B 36.800 -61.778 64.232 1.00 19.78 C
ATOM 208 CD2 LEU L 27B 39.092 -60.808 64.132 1.00 17.87 C
ATOM 209 N LEU L 27C 37.724 -56.400 66.969 1.00 19.63 N
ATOM 210 CA LEU L 27C 37.131 -55.083 67.175 1.00 20.26 C
ATOM 211 C LEU L 27C 37.944 -54.067 66.374 1.00 20.73 C
ATOM 212 O LEU L 27C 39.171 -54.024 66.472 1.00 20.62 O
ATOM 213 CB LEU L 27C 37.138 -54.718 68.661 1.00 22.61 C
ATOM 214 CG LEU L 27C 36.423 -53.419 69.039 1.00 24.16 C
ATOM 215 CD1 LEU L 27C 34.952 -53.510 68.654 1.00 24.09 C
ATOM 216 CD2 LEU L 27C 36.566 -53.177 70.537 1.00 27.61 C
ATOM 217 N TYR L 27D 37.260 -53.262 65.569 1.00 20.20 N
ATOM 218 CA TYR L 27D 37.934 -52.272 64.739 1.00 23.42 C
ATOM 219 C TYR L 27D 37.992 -50.911 65.437 1.00 23.19 C
ATOM 220 O TYR L 27D 37.338 -50.704 66.456 1.00 23.52 O
ATOM 221 CB TYR L 27D 37.225 -52.153 63.384 1.00 25.39 C
ATOM 222 CG TYR L 27D 38.067 -51.489 62.322 1.00 30.37 C
ATOM 223 CD1 TYR L 27D 39.299 -52.023 61.955 1.00 34.82 C
ATOM 224 CD2 TYR L 27D 37.644 -50.321 61.694 1.00 33.19 C
ATOM 225 CE1 TYR L 27D 40.092 -51.411 60.986 1.00 38.04 C
ATOM 226 CE2 TYR L 27D 38.430 -49.698 60.725 1.00 34.49 C
ATOM 227 CZ TYR L 27D 39.651 -50.251 60.379 1.00 36.73 C
ATOM 228 OH TYR L 27D 40.432 -49.652 59.424 1.00 41.25 O
ATOM 229 N SER L 27E 38.764 -49.986 64.874 1.00 22.89 N
ATOM 230 CA SER L 27E 38.939 -48.665 65.469 1.00 25.51 C
ATOM 231 C SER L 27E 37.693 -47.781 65.489 1.00 26.55 C
ATOM 232 O SER L 27E 37.672 -46.749 66.171 1.00 27.33 O
ATOM 233 CB SER L 27E 40.095 -47.932 64.782 1.00 22.60 C
ATOM 234 OG SER L 27E 39.841 -47.747 63.403 1.00 29.11 O
ATOM 235 N ASN L 28 36.659 -48.175 64.751 1.00 23.50 N
ATOM 236 CA ASN L 28 35.418 -47.408 64.733 1.00 19.92 C
ATOM 237 C ASN L 28 34.411 -48.040 65.685 1.00 22.34 C
ATOM 238 O ASN L 28 33.274 -47.586 65.794 1.00 25.95 O
ATOM 239 CB ASN L 28 34.831 -47.338 63.321 1.00 19.19 C
ATOM 240 CG ASN L 28 34.676 -48.707 62.680 1.00 22.32 C
ATOM 241 OD1 ASN L 28 34.703 -49.732 63.359 1.00 19.98 O
ATOM 242 ND2 ASN L 28 34.498 -48.726 61.364 1.00 21.69 N
ATOM 243 N GLY L 29 34.835 -49.093 66.374 1.00 23.30 N
ATOM 244 CA GLY L 29 33.957 -49.746 67.329 1.00 23.12 C
ATOM 245 C GLY L 29 33.135 -50.912 66.810 1.00 25.74 C
ATOM 246 O GLY L 29 32.347 -51.500 67.555 1.00 22.95 O
ATOM 247 N LYS L 30 33.312 -51.256 65.540 1.00 25.83 N
ATOM 248 CA LYS L 30 32.569 -52.365 64.955 1.00 26.77 C
ATOM 249 C LYS L 30 33.457 -53.594 64.859 1.00 26.51 C
ATOM 250 O LYS L 30 34.679 -53.480 64.765 1.00 24.03 O
ATOM 251 CB LYS L 30 32.067 -51.986 63.559 1.00 28.32 C
ATOM 252 CG LYS L 30 31.178 -50.751 63.536 1.00 34.89 C
ATOM 253 CD LYS L 30 30.679 -50.455 62.128 1.00 43.34 C
ATOM 254 CE LYS L 30 29.806 -49.203 62.098 1.00 47.80 C
ATOM 255 NZ LYS L 30 28.635 -49.306 63.020 1.00 45.05 N
ATOM 256 N THR L 31 32.845 -54.770 64.898 1.00 24.46 N
ATOM 257 CA THR L 31 33.599 -56.007 64.785 1.00 25.48 C
ATOM 258 C THR L 31 33.202 -56.707 63.483 1.00 25.18 C
ATOM 259 O THR L 31 32.079 -57.202 63.333 1.00 22.28 O
ATOM 260 CB THR L 31 33.373 -56.919 66.023 1.00 27.75 C
ATOM 261 OG1 THR L 31 33.767 -58.263 65.715 1.00 28.87 O
ATOM 262 CG2 THR L 31 31.927 -56.887 66.458 1.00 35.45 C
ATOM 263 N TYR L 32 34.136 -56.721 62.534 1.00 21.74 N
ATOM 264 CA TYR L 32 33.899 -57.318 61.228 1.00 21.62 C
ATOM 265 C TYR L 32 34.080 -58.833 61.170 1.00 20.47 C
ATOM 266 O TYR L 32 35.134 -59.328 60.783 1.00 20.35 O
ATOM 267 CB TYR L 32 34.803 -56.655 60.182 1.00 25.26 C
ATOM 268 CG TYR L 32 34.597 -55.162 60.051 1.00 29.46 C
ATOM 269 CD1 TYR L 32 33.321 -54.625 59.890 1.00 30.70 C
ATOM 270 CD2 TYR L 32 35.678 -54.285 60.080 1.00 32.63 C
ATOM 271 CE1 TYR L 32 33.125 -53.255 59.762 1.00 29.14 C
ATOM 272 CE2 TYR L 32 35.493 -52.913 59.951 1.00 31.78 C
ATOM 273 CZ TYR L 32 34.215 -52.405 59.794 1.00 32.44 C
ATOM 274 OH TYR L 32 34.030 -51.048 59.669 1.00 25.41 O
ATOM 275 N LEU L 33 33.048 -59.565 61.574 1.00 16.46 N
ATOM 276 CA LEU L 33 33.080 -61.018 61.528 1.00 14.29 C
ATOM 277 C LEU L 33 31.840 -61.469 60.763 1.00 14.89 C
ATOM 278 O LEU L 33 30.708 -61.132 61.141 1.00 14.83 O
ATOM 279 CB LEU L 33 33.049 -61.634 62.930 1.00 19.02 C
ATOM 280 CG LEU L 33 32.957 -63.154 62.757 1.00 24.27 C
ATOM 281 CD1 LEU L 33 34.354 -63.753 62.648 1.00 23.06 C
ATOM 282 CD2 LEU L 33 32.195 -63.756 63.890 1.00 26.31 C
ATOM 283 N ASN L 34 32.061 -62.233 59.699 1.00 14.89 N
ATOM 284 CA ASN L 34 30.985 -62.721 58.847 1.00 13.35 C
ATOM 285 C ASN L 34 30.926 -64.239 58.855 1.00 16.45 C
ATOM 286 O ASN L 34 31.891 -64.916 59.239 1.00 12.72 O
ATOM 287 CB ASN L 34 31.206 -62.281 57.394 1.00 17.67 C
ATOM 288 CG ASN L 34 31.584 -60.814 57.265 1.00 21.95 C
ATOM 289 OD1 ASN L 34 30.744 -59.925 57.385 1.00 20.35 O
ATOM 290 ND2 ASN L 34 32.862 -60.560 57.019 1.00 26.68 N
ATOM 291 N TRP L 35 29.783 -64.761 58.420 1.00 14.93 N
ATOM 292 CA TRP L 35 29.576 -66.196 58.302 1.00 15.61 C
ATOM 293 C TRP L 35 29.091 -66.467 56.883 1.00 17.92 C
ATOM 294 O TRP L 35 28.186 -65.792 56.387 1.00 16.60 O
ATOM 295 CB TRP L 35 28.524 -66.706 59.288 1.00 16.06 C
ATOM 296 CG TRP L 35 28.956 -66.744 60.705 1.00 14.52 C
ATOM 297 CD1 TRP L 35 28.703 -65.809 61.662 1.00 16.42 C
ATOM 298 CD2 TRP L 35 29.689 -67.793 61.350 1.00 17.46 C
ATOM 299 NE1 TRP L 35 29.224 -66.212 62.868 1.00 14.83 N
ATOM 300 CE2 TRP L 35 29.836 -67.427 62.704 1.00 16.93 C
ATOM 301 CE3 TRP L 35 30.235 -69.008 60.915 1.00 17.09 C
ATOM 302 CZ2 TRP L 35 30.506 -68.234 63.632 1.00 14.21 C
ATOM 303 CZ3 TRP L 35 30.902 -69.812 61.840 1.00 21.53 C
ATOM 304 CH2 TRP L 35 31.029 -69.419 63.182 1.00 18.08 C
ATOM 305 N LEU L 36 29.704 -67.452 56.235 1.00 16.84 N
ATOM 306 CA LEU L 36 29.334 -67.835 54.876 1.00 17.45 C
ATOM 307 C LEU L 36 28.843 -69.276 54.865 1.00 14.78 C
ATOM 308 O LEU L 36 29.199 -70.084 55.727 1.00 13.21 O
ATOM 309 CB LEU L 36 30.537 -67.759 53.929 1.00 14.08 C
ATOM 310 CG LEU L 36 31.383 -66.496 53.794 1.00 21.94 C
ATOM 311 CD1 LEU L 36 32.638 -66.837 52.993 1.00 23.95 C
ATOM 312 CD2 LEU L 36 30.591 -65.399 53.111 1.00 22.33 C
ATOM 313 N LEU L 37 28.033 -69.586 53.866 1.00 13.66 N
ATOM 314 CA LEU L 37 27.517 -70.921 53.680 1.00 14.99 C
ATOM 315 C LEU L 37 27.772 -71.265 52.231 1.00 14.95 C
ATOM 316 O LEU L 37 27.392 -70.515 51.335 1.00 16.53 O
ATOM 317 CB LEU L 37 26.008 -70.987 53.951 1.00 16.19 C
ATOM 318 CG LEU L 37 25.327 -72.260 53.420 1.00 14.96 C
ATOM 319 CD1 LEU L 37 25.946 -73.495 54.060 1.00 17.06 C
ATOM 320 CD2 LEU L 37 23.831 -72.199 53.704 1.00 18.19 C
ATOM 321 N GLN L 38 28.446 -72.382 52.002 1.00 14.33 N
ATOM 322 CA GLN L 38 28.707 -72.834 50.645 1.00 15.88 C
ATOM 323 C GLN L 38 27.991 -74.166 50.492 1.00 15.91 C
ATOM 324 O GLN L 38 28.443 -75.186 51.014 1.00 18.08 O
ATOM 325 CB GLN L 38 30.213 -73.016 50.401 1.00 17.23 C
ATOM 326 CG GLN L 38 30.550 -73.693 49.071 1.00 15.66 C
ATOM 327 CD GLN L 38 32.035 -73.633 48.729 1.00 15.82 C
ATOM 328 OE1 GLN L 38 32.887 -73.902 49.571 1.00 18.16 O
ATOM 329 NE2 GLN L 38 32.345 -73.290 47.483 1.00 16.89 N
ATOM 330 N ARG L 39 26.856 -74.145 49.805 1.00 14.18 N
ATOM 331 CA ARG L 39 26.089 -75.358 49.568 1.00 20.33 C
ATOM 332 C ARG L 39 26.806 -76.159 48.486 1.00 21.95 C
ATOM 333 O ARG L 39 27.536 -75.601 47.669 1.00 22.64 O
ATOM 334 CB ARG L 39 24.670 -75.021 49.100 1.00 19.28 C
ATOM 335 CG ARG L 39 23.832 -74.263 50.120 1.00 26.32 C
ATOM 336 CD ARG L 39 22.353 -74.293 49.745 1.00 30.01 C
ATOM 337 NE ARG L 39 21.495 -73.758 50.802 1.00 37.68 N
ATOM 338 CZ ARG L 39 21.208 -72.468 50.963 1.00 42.04 C
ATOM 339 NH1 ARG L 39 21.707 -71.562 50.130 1.00 42.72 N
ATOM 340 NH2 ARG L 39 20.420 -72.084 51.960 1.00 41.07 N
ATOM 341 N PRO L 40 26.608 -77.482 48.468 1.00 25.36 N
ATOM 342 CA PRO L 40 27.256 -78.330 47.463 1.00 26.92 C
ATOM 343 C PRO L 40 27.087 -77.801 46.038 1.00 27.27 C
ATOM 344 O PRO L 40 25.986 -77.445 45.626 1.00 29.19 O
ATOM 345 CB PRO L 40 26.572 -79.677 47.669 1.00 27.23 C
ATOM 346 CG PRO L 40 26.321 -79.685 49.147 1.00 27.26 C
ATOM 347 CD PRO L 40 25.794 -78.289 49.395 1.00 24.09 C
ATOM 348 N GLY L 41 28.190 -77.738 45.299 1.00 28.99 N
ATOM 349 CA GLY L 41 28.144 -77.270 43.922 1.00 29.79 C
ATOM 350 C GLY L 41 27.787 -75.807 43.725 1.00 33.61 C
ATOM 351 O GLY L 41 27.329 -75.416 42.650 1.00 34.06 O
ATOM 352 N GLN L 42 27.998 -74.990 44.752 1.00 32.20 N
ATOM 353 CA GLN L 42 27.683 -73.571 44.655 1.00 29.83 C
ATOM 354 C GLN L 42 28.766 -72.680 45.249 1.00 27.43 C
ATOM 355 O GLN L 42 29.657 -73.142 45.966 1.00 25.20 O
ATOM 356 CB GLN L 42 26.345 -73.285 45.336 1.00 30.55 C
ATOM 357 CG GLN L 42 25.176 -74.013 44.696 1.00 40.46 C
ATOM 358 CD GLN L 42 23.840 -73.551 45.235 1.00 46.52 C
ATOM 359 OE1 GLN L 42 23.516 -72.363 45.182 1.00 53.14 O
ATOM 360 NE2 GLN L 42 23.052 -74.486 45.755 1.00 48.57 N
ATOM 361 N SER L 43 28.694 -71.395 44.931 1.00 24.38 N
ATOM 362 CA SER L 43 29.669 -70.452 45.444 1.00 25.35 C
ATOM 363 C SER L 43 29.278 -70.069 46.869 1.00 22.38 C
ATOM 364 O SER L 43 28.118 -70.200 47.266 1.00 17.94 O
ATOM 365 CB SER L 43 29.711 -69.206 44.557 1.00 27.87 C
ATOM 366 OG SER L 43 28.468 -68.532 44.589 1.00 37.63 O
ATOM 367 N PRO L 44 30.250 -69.617 47.669 1.00 20.31 N
ATOM 368 CA PRO L 44 29.924 -69.231 49.044 1.00 20.54 C
ATOM 369 C PRO L 44 28.864 -68.134 49.040 1.00 20.65 C
ATOM 370 O PRO L 44 28.762 -67.352 48.087 1.00 17.85 O
ATOM 371 CB PRO L 44 31.261 -68.734 49.592 1.00 17.98 C
ATOM 372 CG PRO L 44 32.259 -69.577 48.850 1.00 19.43 C
ATOM 373 CD PRO L 44 31.703 -69.557 47.434 1.00 22.70 C
ATOM 374 N LYS L 45 28.073 -68.088 50.103 1.00 17.24 N
ATOM 375 CA LYS L 45 27.031 -67.087 50.234 1.00 16.32 C
ATOM 376 C LYS L 45 27.064 -66.561 51.661 1.00 14.58 C
ATOM 377 O LYS L 45 27.066 -67.339 52.617 1.00 11.26 O
ATOM 378 CB LYS L 45 25.658 -67.697 49.943 1.00 22.35 C
ATOM 379 CG LYS L 45 24.545 -66.675 49.951 1.00 28.96 C
ATOM 380 CD LYS L 45 23.182 -67.305 49.769 1.00 37.31 C
ATOM 381 CE LYS L 45 22.114 -66.228 49.602 1.00 43.23 C
ATOM 382 NZ LYS L 45 22.103 -65.268 50.745 1.00 43.54 N
ATOM 383 N ARG L 46 27.106 -65.244 51.812 1.00 12.76 N
ATOM 384 CA ARG L 46 27.137 -64.675 53.149 1.00 16.71 C
ATOM 385 C ARG L 46 25.749 -64.741 53.798 1.00 14.60 C
ATOM 386 O ARG L 46 24.736 -64.443 53.156 1.00 14.89 O
ATOM 387 CB ARG L 46 27.634 -63.227 53.104 1.00 14.67 C
ATOM 388 CG ARG L 46 28.102 -62.707 54.457 1.00 15.93 C
ATOM 389 CD ARG L 46 28.580 -61.277 54.358 1.00 15.47 C
ATOM 390 NE ARG L 46 27.464 -60.352 54.188 1.00 16.37 N
ATOM 391 CZ ARG L 46 27.604 -59.059 53.931 1.00 16.05 C
ATOM 392 NH1 ARG L 46 28.820 -58.536 53.811 1.00 13.47 N
ATOM 393 NH2 ARG L 46 26.530 -58.290 53.796 1.00 12.81 N
ATOM 394 N LEU L 47 25.725 -65.148 55.067 1.00 14.40 N
ATOM 395 CA LEU L 47 24.494 -65.271 55.849 1.00 15.42 C
ATOM 396 C LEU L 47 24.435 -64.184 56.915 1.00 18.73 C
ATOM 397 O LEU L 47 23.389 -63.565 57.138 1.00 19.02 O
ATOM 398 CB LEU L 47 24.441 -66.622 56.567 1.00 12.06 C
ATOM 399 CG LEU L 47 24.517 -67.908 55.743 1.00 19.55 C
ATOM 400 CD1 LEU L 47 24.405 -69.102 56.682 1.00 18.49 C
ATOM 401 CD2 LEU L 47 23.401 -67.940 54.703 1.00 19.39 C
ATOM 402 N ILE L 48 25.576 -63.967 57.566 1.00 18.50 N
ATOM 403 CA ILE L 48 25.696 -62.997 58.645 1.00 16.46 C
ATOM 404 C ILE L 48 26.923 -62.102 58.520 1.00 16.98 C
ATOM 405 O ILE L 48 27.994 -62.567 58.152 1.00 14.42 O
ATOM 406 CB ILE L 48 25.792 -63.727 60.004 1.00 18.05 C
ATOM 407 CG1 ILE L 48 24.500 -64.498 60.268 1.00 19.86 C
ATOM 408 CG2 ILE L 48 26.094 -62.733 61.117 1.00 17.08 C
ATOM 409 CD1 ILE L 48 24.476 -65.226 61.588 1.00 25.31 C
ATOM 410 N TYR L 49 26.755 -60.820 58.836 1.00 16.21 N
ATOM 411 CA TYR L 49 27.860 -59.861 58.815 1.00 17.49 C
ATOM 412 C TYR L 49 27.797 -59.030 60.103 1.00 17.53 C
ATOM 413 O TYR L 49 26.768 -59.005 60.778 1.00 18.53 O
ATOM 414 CB TYR L 49 27.795 -58.951 57.579 1.00 15.12 C
ATOM 415 CG TYR L 49 26.573 -58.061 57.475 1.00 18.97 C
ATOM 416 CD1 TYR L 49 25.349 -58.564 57.034 1.00 19.08 C
ATOM 417 CD2 TYR L 49 26.652 -56.703 57.789 1.00 18.51 C
ATOM 418 CE1 TYR L 49 24.229 -57.729 56.902 1.00 18.77 C
ATOM 419 CE2 TYR L 49 25.546 -55.865 57.664 1.00 22.10 C
ATOM 420 CZ TYR L 49 24.342 -56.382 57.220 1.00 22.13 C
ATOM 421 OH TYR L 49 23.260 -55.548 57.098 1.00 24.02 O
ATOM 422 N LEU L 50 28.892 -58.356 60.443 1.00 18.75 N
ATOM 423 CA LEU L 50 28.956 -57.564 61.668 1.00 18.23 C
ATOM 424 C LEU L 50 28.513 -58.394 62.875 1.00 19.33 C
ATOM 425 O LEU L 50 27.791 -57.915 63.749 1.00 17.93 O
ATOM 426 CB LEU L 50 28.094 -56.304 61.543 1.00 20.23 C
ATOM 427 CG LEU L 50 28.676 -55.197 60.656 1.00 17.31 C
ATOM 428 CD1 LEU L 50 27.644 -54.091 60.474 1.00 18.72 C
ATOM 429 CD2 LEU L 50 29.959 -54.651 61.286 1.00 7.48 C
ATOM 430 N VAL L 51 28.933 -59.655 62.888 1.00 18.13 N
ATOM 431 CA VAL L 51 28.642 -60.583 63.979 1.00 16.91 C
ATOM 432 C VAL L 51 27.223 -61.127 64.107 1.00 16.58 C
ATOM 433 O VAL L 51 27.032 -62.332 64.264 1.00 18.45 O
ATOM 434 CB VAL L 51 29.028 -59.960 65.356 1.00 22.06 C
ATOM 435 CG1 VAL L 51 28.727 -60.940 66.483 1.00 16.84 C
ATOM 436 CG2 VAL L 51 30.508 -59.596 65.370 1.00 19.42 C
ATOM 437 N SER L 52 26.221 -60.262 64.032 1.00 16.63 N
ATOM 438 CA SER L 52 24.859 -60.736 64.234 1.00 19.17 C
ATOM 439 C SER L 52 23.795 -60.243 63.270 1.00 19.81 C
ATOM 440 O SER L 52 22.615 -60.504 63.483 1.00 21.93 O
ATOM 441 CB SER L 52 24.429 -60.384 65.656 1.00 20.87 C
ATOM 442 OG SER L 52 24.495 -58.978 65.843 1.00 21.76 O
ATOM 443 N LYS L 53 24.189 -59.534 62.220 1.00 20.59 N
ATOM 444 CA LYS L 53 23.208 -59.034 61.266 1.00 23.42 C
ATOM 445 C LYS L 53 22.959 -60.023 60.138 1.00 22.07 C
ATOM 446 O LYS L 53 23.893 -60.471 59.476 1.00 24.54 O
ATOM 447 CB LYS L 53 23.658 -57.689 60.694 1.00 25.03 C
ATOM 448 CG LYS L 53 23.530 -56.546 61.680 1.00 29.66 C
ATOM 449 CD LYS L 53 23.997 -55.234 61.088 1.00 33.90 C
ATOM 450 CE LYS L 53 23.662 -54.086 62.022 1.00 42.85 C
ATOM 451 NZ LYS L 53 24.146 -54.353 63.410 1.00 47.15 N
ATOM 452 N LEU L 54 21.691 -60.358 59.929 1.00 20.82 N
ATOM 453 CA LEU L 54 21.308 -61.291 58.883 1.00 22.53 C
ATOM 454 C LEU L 54 21.213 -60.627 57.521 1.00 25.63 C
ATOM 455 O LEU L 54 20.623 -59.553 57.379 1.00 23.36 O
ATOM 456 CB LEU L 54 19.960 -61.936 59.207 1.00 24.44 C
ATOM 457 CG LEU L 54 19.934 -63.145 60.146 1.00 28.62 C
ATOM 458 CD1 LEU L 54 20.540 -62.775 61.490 1.00 32.75 C
ATOM 459 CD2 LEU L 54 18.495 -63.619 60.315 1.00 29.37 C
ATOM 460 N ASP L 55 21.812 -61.268 56.523 1.00 23.13 N
ATOM 461 CA ASP L 55 21.755 -60.769 55.160 1.00 22.15 C
ATOM 462 C ASP L 55 20.329 -60.994 54.675 1.00 23.92 C
ATOM 463 O ASP L 55 19.586 -61.780 55.269 1.00 20.33 O
ATOM 464 CB ASP L 55 22.748 -61.528 54.276 1.00 19.91 C
ATOM 465 CG ASP L 55 24.145 -60.926 54.325 1.00 21.77 C
ATOM 466 OD1 ASP L 55 24.326 -59.815 53.789 1.00 20.55 O
ATOM 467 OD2 ASP L 55 25.055 -61.553 54.907 1.00 23.10 O
ATOM 468 N SER L 56 19.950 -60.301 53.607 1.00 26.03 N
ATOM 469 CA SER L 56 18.608 -60.417 53.047 1.00 31.82 C
ATOM 470 C SER L 56 18.335 -61.838 52.574 1.00 31.81 C
ATOM 471 O SER L 56 19.192 -62.464 51.954 1.00 35.23 O
ATOM 472 CB SER L 56 18.449 -59.468 51.859 1.00 33.67 C
ATOM 473 OG SER L 56 19.015 -58.203 52.143 1.00 43.12 O
ATOM 474 N GLY L 57 17.139 -62.338 52.862 1.00 33.54 N
ATOM 475 CA GLY L 57 16.772 -63.675 52.431 1.00 33.25 C
ATOM 476 C GLY L 57 17.109 -64.784 53.405 1.00 34.17 C
ATOM 477 O GLY L 57 16.551 -65.879 53.321 1.00 37.35 O
ATOM 478 N VAL L 58 18.021 -64.510 54.329 1.00 31.48 N
ATOM 479 CA VAL L 58 18.423 -65.506 55.312 1.00 26.25 C
ATOM 480 C VAL L 58 17.331 -65.689 56.374 1.00 29.64 C
ATOM 481 O VAL L 58 16.869 -64.725 56.983 1.00 28.05 O
ATOM 482 CB VAL L 58 19.759 -65.097 55.985 1.00 26.35 C
ATOM 483 CG1 VAL L 58 20.205 -66.161 56.973 1.00 22.70 C
ATOM 484 CG2 VAL L 58 20.828 -64.882 54.918 1.00 18.63 C
ATOM 485 N PRO L 59 16.897 -66.940 56.598 1.00 30.43 N
ATOM 486 CA PRO L 59 15.861 -67.282 57.578 1.00 32.06 C
ATOM 487 C PRO L 59 16.163 -66.855 59.015 1.00 32.74 C
ATOM 488 O PRO L 59 17.315 -66.843 59.451 1.00 33.07 O
ATOM 489 CB PRO L 59 15.756 -68.796 57.446 1.00 33.06 C
ATOM 490 CG PRO L 59 16.066 -69.021 56.008 1.00 32.07 C
ATOM 491 CD PRO L 59 17.257 -68.123 55.799 1.00 29.67 C
ATOM 492 N ASP L 60 15.101 -66.522 59.740 1.00 31.16 N
ATOM 493 CA ASP L 60 15.170 -66.093 61.134 1.00 32.37 C
ATOM 494 C ASP L 60 15.775 -67.190 62.023 1.00 30.41 C
ATOM 495 O ASP L 60 16.125 -66.942 63.179 1.00 27.13 O
ATOM 496 CB ASP L 60 13.749 -65.753 61.610 1.00 40.86 C
ATOM 497 CG ASP L 60 13.724 -65.041 62.950 1.00 49.34 C
ATOM 498 OD1 ASP L 60 14.282 -65.580 63.930 1.00 54.47 O
ATOM 499 OD2 ASP L 60 13.131 -63.942 63.027 1.00 53.40 O
ATOM 500 N ARG L 61 15.887 -68.403 61.483 1.00 28.18 N
ATOM 501 CA ARG L 61 16.440 -69.535 62.229 1.00 26.81 C
ATOM 502 C ARG L 61 17.911 -69.334 62.567 1.00 24.82 C
ATOM 503 O ARG L 61 18.428 -69.935 63.513 1.00 24.48 O
ATOM 504 CB ARG L 61 16.319 -70.830 61.424 1.00 30.87 C
ATOM 505 CG ARG L 61 14.932 -71.152 60.911 1.00 37.65 C
ATOM 506 CD ARG L 61 14.846 -72.622 60.535 1.00 39.88 C
ATOM 507 NE ARG L 61 15.915 -73.034 59.626 1.00 39.46 N
ATOM 508 CZ ARG L 61 15.966 -72.707 58.342 1.00 36.67 C
ATOM 509 NH1 ARG L 61 15.009 -71.960 57.808 1.00 43.76 N
ATOM 510 NH2 ARG L 61 16.968 -73.130 57.591 1.00 32.38 N
ATOM 511 N PHE L 62 18.593 -68.510 61.781 1.00 21.85 N
ATOM 512 CA PHE L 62 20.010 -68.262 62.021 1.00 24.54 C
ATOM 513 C PHE L 62 20.215 -67.098 62.972 1.00 23.56 C
ATOM 514 O PHE L 62 19.521 -66.083 62.896 1.00 20.33 O
ATOM 515 CB PHE L 62 20.751 -67.977 60.708 1.00 21.32 C
ATOM 516 CG PHE L 62 20.878 -69.173 59.813 1.00 24.06 C
ATOM 517 CD1 PHE L 62 19.819 -69.574 59.006 1.00 25.50 C
ATOM 518 CD2 PHE L 62 22.054 -69.915 59.790 1.00 26.55 C
ATOM 519 CE1 PHE L 62 19.934 -70.700 58.189 1.00 24.36 C
ATOM 520 CE2 PHE L 62 22.176 -71.041 58.978 1.00 25.25 C
ATOM 521 CZ PHE L 62 21.116 -71.433 58.178 1.00 21.45 C
ATOM 522 N THR L 63 21.170 -67.265 63.876 1.00 22.89 N
ATOM 523 CA THR L 63 21.497 -66.233 64.841 1.00 24.67 C
ATOM 524 C THR L 63 22.999 -66.216 65.091 1.00 22.41 C
ATOM 525 O THR L 63 23.614 -67.256 65.323 1.00 22.38 O
ATOM 526 CB THR L 63 20.752 -66.468 66.169 1.00 27.75 C
ATOM 527 OG1 THR L 63 19.346 -66.292 65.955 1.00 34.04 O
ATOM 528 CG2 THR L 63 21.222 -65.487 67.233 1.00 30.09 C
ATOM 529 N GLY L 64 23.585 -65.027 65.024 1.00 23.19 N
ATOM 530 CA GLY L 64 25.007 -64.883 65.263 1.00 17.74 C
ATOM 531 C GLY L 64 25.256 -64.055 66.510 1.00 20.94 C
ATOM 532 O GLY L 64 24.540 -63.093 66.779 1.00 20.63 O
ATOM 533 N SER L 65 26.264 -64.434 67.287 1.00 20.93 N
ATOM 534 CA SER L 65 26.605 -63.696 68.494 1.00 20.49 C
ATOM 535 C SER L 65 28.092 -63.855 68.785 1.00 20.64 C
ATOM 536 O SER L 65 28.802 -64.564 68.077 1.00 20.55 O
ATOM 537 CB SER L 65 25.789 -64.210 69.677 1.00 19.60 C
ATOM 538 OG SER L 65 26.145 -65.543 69.980 1.00 26.02 O
ATOM 539 N GLY L 66 28.562 -63.195 69.833 1.00 21.77 N
ATOM 540 CA GLY L 66 29.965 -63.297 70.184 1.00 22.74 C
ATOM 541 C GLY L 66 30.568 -61.923 70.338 1.00 24.85 C
ATOM 542 O GLY L 66 29.900 -60.913 70.112 1.00 24.29 O
ATOM 543 N SER L 67 31.839 -61.873 70.705 1.00 27.01 N
ATOM 544 CA SER L 67 32.490 -60.590 70.896 1.00 30.72 C
ATOM 545 C SER L 67 33.982 -60.792 71.097 1.00 29.06 C
ATOM 546 O SER L 67 34.412 -61.823 71.611 1.00 27.98 O
ATOM 547 CB SER L 67 31.880 -59.894 72.120 1.00 32.77 C
ATOM 548 OG SER L 67 32.403 -58.594 72.298 1.00 40.98 O
ATOM 549 N GLY L 68 34.770 -59.807 70.680 1.00 29.28 N
ATOM 550 CA GLY L 68 36.208 -59.897 70.847 1.00 28.85 C
ATOM 551 C GLY L 68 36.905 -60.977 70.046 1.00 29.75 C
ATOM 552 O GLY L 68 37.318 -60.743 68.906 1.00 32.70 O
ATOM 553 N THR L 69 37.050 -62.160 70.639 1.00 30.01 N
ATOM 554 CA THR L 69 37.727 -63.263 69.963 1.00 27.46 C
ATOM 555 C THR L 69 36.896 -64.543 69.862 1.00 25.79 C
ATOM 556 O THR L 69 37.335 -65.512 69.245 1.00 24.35 O
ATOM 557 CB THR L 69 39.055 -63.619 70.670 1.00 27.91 C
ATOM 558 OG1 THR L 69 38.776 -64.172 71.962 1.00 26.61 O
ATOM 559 CG2 THR L 69 39.924 -62.380 70.833 1.00 24.72 C
ATOM 560 N ASP L 70 35.709 -64.553 70.466 1.00 22.97 N
ATOM 561 CA ASP L 70 34.852 -65.740 70.427 1.00 25.61 C
ATOM 562 C ASP L 70 33.499 -65.428 69.819 1.00 22.62 C
ATOM 563 O ASP L 70 32.802 -64.521 70.269 1.00 22.80 O
ATOM 564 CB ASP L 70 34.665 -66.325 71.828 1.00 28.61 C
ATOM 565 CG ASP L 70 35.945 -66.911 72.384 1.00 37.03 C
ATOM 566 OD1 ASP L 70 36.878 -66.134 72.679 1.00 40.10 O
ATOM 567 OD2 ASP L 70 36.023 -68.152 72.517 1.00 41.86 O
ATOM 568 N PHE L 71 33.129 -66.206 68.806 1.00 20.71 N
ATOM 569 CA PHE L 71 31.880 -66.004 68.083 1.00 20.13 C
ATOM 570 C PHE L 71 31.155 -67.313 67.858 1.00 21.75 C
ATOM 571 O PHE L 71 31.782 -68.362 67.736 1.00 22.22 O
ATOM 572 CB PHE L 71 32.193 -65.344 66.748 1.00 19.20 C
ATOM 573 CG PHE L 71 33.037 -64.121 66.885 1.00 17.28 C
ATOM 574 CD1 PHE L 71 32.466 -62.906 67.238 1.00 18.11 C
ATOM 575 CD2 PHE L 71 34.414 -64.194 66.723 1.00 19.84 C
ATOM 576 CE1 PHE L 71 33.252 -61.779 67.433 1.00 18.03 C
ATOM 577 CE2 PHE L 71 35.210 -63.074 66.917 1.00 17.27 C
ATOM 578 CZ PHE L 71 34.626 -61.862 67.274 1.00 18.64 C
ATOM 579 N THR L 72 29.829 -67.247 67.788 1.00 21.07 N
ATOM 580 CA THR L 72 29.031 -68.447 67.599 1.00 22.12 C
ATOM 581 C THR L 72 27.878 -68.249 66.634 1.00 21.14 C
ATOM 582 O THR L 72 27.183 -67.230 66.680 1.00 22.76 O
ATOM 583 CB THR L 72 28.430 -68.941 68.937 1.00 24.07 C
ATOM 584 OG1 THR L 72 29.470 -69.078 69.913 1.00 25.91 O
ATOM 585 CG2 THR L 72 27.740 -70.294 68.744 1.00 19.04 C
ATOM 586 N LEU L 73 27.687 -69.237 65.764 1.00 18.96 N
ATOM 587 CA LEU L 73 26.596 -69.240 64.799 1.00 20.26 C
ATOM 588 C LEU L 73 25.627 -70.309 65.295 1.00 23.48 C