diff --git a/CMakeLists.txt b/CMakeLists.txt
index 0f40963..441fcbf 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -158,6 +158,7 @@ if(WIN32)
     INTERFACE
       NOMINMAX
       _CRT_SECURE_NO_WARNINGS
+      _DISABLE_CONSTEXPR_MUTEX_CONSTRUCTOR # https://github.com/gabime/spdlog/issues/3212
   )
 endif()
 
diff --git a/src/cooler_file_writer.cpp b/src/cooler_file_writer.cpp
index 9c74df9..f7b72b5 100644
--- a/src/cooler_file_writer.cpp
+++ b/src/cooler_file_writer.cpp
@@ -112,17 +112,11 @@ void CoolerFileWriter::finalize([[maybe_unused]] std::string_view log_lvl_str,
 
   assert(_w.has_value());
   // NOLINTBEGIN(*-unchecked-optional-access)
-#ifndef _WIN32
-  // TODO fixme
-  // There is something very odd going on when trying to call most spdlog functions from within
-  // Python bindings on recent versions of Windows.
-  // Possibly related to https://github.com/gabime/spdlog/issues/3212
   const auto log_lvl = spdlog::level::from_str(normalize_log_lvl(log_lvl_str));
   const auto previous_lvl = spdlog::default_logger()->level();
   spdlog::default_logger()->set_level(log_lvl);
 
   SPDLOG_INFO(FMT_STRING("finalizing file \"{}\"..."), _path);
-#endif
   try {
     std::visit(
         [&](const auto &num) {
@@ -131,17 +125,14 @@ void CoolerFileWriter::finalize([[maybe_unused]] std::string_view log_lvl_str,
         },
         _w->open("0").pixel_variant());
   } catch (...) {
-#ifndef _WIN32
     spdlog::default_logger()->set_level(previous_lvl);
-#endif
     throw;
   }
 
   _finalized = true;
   SPDLOG_INFO(FMT_STRING("merged {} cooler(s) into file \"{}\""), _w->cells().size(), _path);
-#ifndef _WIN32
   spdlog::default_logger()->set_level(previous_lvl);
-#endif
+
   const std::string sclr_path{_w->path()};
   _w.reset();
   std::filesystem::remove(sclr_path);  // NOLINT
diff --git a/src/hic_file_writer.cpp b/src/hic_file_writer.cpp
index d4ebe99..f09a7d9 100644
--- a/src/hic_file_writer.cpp
+++ b/src/hic_file_writer.cpp
@@ -52,30 +52,20 @@ void HiCFileWriter::finalize([[maybe_unused]] std::string_view log_lvl_str) {
         fmt::format(FMT_STRING("finalize() was already called on file \"{}\""), _w.path()));
   }
 
-#ifndef _WIN32
-  // TODO fixme
-  // There is something very odd going on when trying to call most spdlog functions from within
-  // Python bindings on recent versions of Windows.
-  // Possibly related to https://github.com/gabime/spdlog/issues/3212
   const auto log_lvl = spdlog::level::from_str(normalize_log_lvl(log_lvl_str));
   const auto previous_lvl = spdlog::default_logger()->level();
   spdlog::default_logger()->set_level(log_lvl);
 
   SPDLOG_INFO(FMT_STRING("finalizing file \"{}\"..."), _w.path());
-#endif
   try {
     _w.serialize();
     _finalized = true;
   } catch (...) {
-#ifndef _WIN32
     spdlog::default_logger()->set_level(previous_lvl);
-#endif
     throw;
   }
   SPDLOG_INFO(FMT_STRING("successfully finalized \"{}\"!"), _w.path());
-#ifndef _WIN32
   spdlog::default_logger()->set_level(previous_lvl);
-#endif
 }
 
 std::filesystem::path HiCFileWriter::path() const noexcept {