diff --git a/Makefile b/Makefile
index b15649e2..7ba735dd 100644
--- a/Makefile
+++ b/Makefile
@@ -7,3 +7,17 @@ lint:
 test:
 	@npm run build
 	@coverage run --source=pyca --omit='*.html' -m unittest discover -s tests
+
+build:
+	@npm ci
+	@npm run build
+
+pypi: clean build
+	@python setup.py sdist
+	@printf "\nUpload to PyPI with \"twine upload dist/$$(python setup.py --fullname).tar.gz\"\n"
+
+clean:
+	@python setup.py clean --all
+	@rm -rf node_modules pyca/ui/static
+
+PHONY: all lint test build pypi clean
diff --git a/docs/pypi.rst b/docs/pypi.rst
new file mode 100644
index 00000000..a7c308ed
--- /dev/null
+++ b/docs/pypi.rst
@@ -0,0 +1,20 @@
+Upload to PyPI_
+===============
+
+The ``Makefile`` includes a ``pypi`` target which builds a clean PyCA package.
+
+So you can simply call
+
+.. code-block:: bash
+
+    make pypi
+
+to build a clean package.
+
+The built package should be found under ``dist`` and can be uploaded to PyPI_, e.g. with Twine_.
+
+For a more detailed explanation about the whole process, take e.g. a look at `Packaging Python Projects`_
+
+.. _PyPI: https://pypi.org
+.. _Twine: https://pypi.org/project/twine/
+.. _Packaging Python Projects: https://packaging.python.org/tutorials/packaging-projects/
diff --git a/docs/readme.rst b/docs/readme.rst
index 1196b64f..52d759e3 100644
--- a/docs/readme.rst
+++ b/docs/readme.rst
@@ -40,3 +40,8 @@ API
 ---
 
 - `API Documentation <apidocs.rst>`_
+
+Developer Information
+---------------------
+
+- `Upload to PyPI <pypi.rst>`_