diff --git a/metapackages/auto-instrumentations-node/README.md b/metapackages/auto-instrumentations-node/README.md
index 60692e339c..00b52837cf 100644
--- a/metapackages/auto-instrumentations-node/README.md
+++ b/metapackages/auto-instrumentations-node/README.md
@@ -171,7 +171,10 @@ registerInstrumentations({
 - [@opentelemetry/instrumentation-dataloader](https://github.com/open-telemetry/opentelemetry-js-contrib/tree/main/plugins/node/instrumentation-dataloader)
 - [@opentelemetry/instrumentation-dns](https://github.com/open-telemetry/opentelemetry-js-contrib/tree/main/plugins/node/opentelemetry-instrumentation-dns)
 - [@opentelemetry/instrumentation-express](https://github.com/open-telemetry/opentelemetry-js-contrib/tree/main/plugins/node/opentelemetry-instrumentation-express)
-- [@opentelemetry/instrumentation-fastify](https://github.com/open-telemetry/opentelemetry-js-contrib/tree/main/plugins/node/opentelemetry-instrumentation-fastify)
+- [@opentelemetry/instrumentation-fastify](https://github.com/open-telemetry/opentelemetry-js-contrib/tree/main/plugins/node/opentelemetry-instrumentation-fastify) (deprecated, default disabled)
+  - This component is **deprecated** in favor of the official instrumentation package [`@fastify/otel`](https://www.npmjs.com/package/@fastify/otel), maintained by the Fastify authors.
+    - Please see [here](https://github.com/fastify/otel?tab=readme-ov-file#usage) for instructions on how to use `@fastify/otel`.
+  - This component will be removed on June 30, 2025
 - [@opentelemetry/instrumentation-fs](https://github.com/open-telemetry/opentelemetry-js-contrib/tree/main/plugins/node/instrumentation-fs) (default disabled)
 - [@opentelemetry/instrumentation-generic-pool](https://github.com/open-telemetry/opentelemetry-js-contrib/tree/main/plugins/node/opentelemetry-instrumentation-generic-pool)
 - [@opentelemetry/instrumentation-graphql](https://github.com/open-telemetry/opentelemetry-js-contrib/tree/main/plugins/node/opentelemetry-instrumentation-graphql)
diff --git a/metapackages/auto-instrumentations-node/src/utils.ts b/metapackages/auto-instrumentations-node/src/utils.ts
index d7e6a0cd6b..c8ffd50c27 100644
--- a/metapackages/auto-instrumentations-node/src/utils.ts
+++ b/metapackages/auto-instrumentations-node/src/utils.ts
@@ -136,7 +136,10 @@ const InstrumentationMap = {
   '@opentelemetry/instrumentation-winston': WinstonInstrumentation,
 };
 
-const defaultExcludedInstrumentations = ['@opentelemetry/instrumentation-fs'];
+const defaultExcludedInstrumentations = [
+  '@opentelemetry/instrumentation-fs',
+  '@opentelemetry/instrumentation-fastify',
+];
 
 // Config types inferred automatically from the first argument of the constructor
 type ConfigArg<T> = T extends new (...args: infer U) => unknown ? U[0] : never;
diff --git a/metapackages/auto-instrumentations-node/test/utils.test.ts b/metapackages/auto-instrumentations-node/test/utils.test.ts
index d2959b6ddd..6be7ed6692 100644
--- a/metapackages/auto-instrumentations-node/test/utils.test.ts
+++ b/metapackages/auto-instrumentations-node/test/utils.test.ts
@@ -30,7 +30,8 @@ describe('utils', () => {
       ).filter(depName => {
         return (
           depName.startsWith('@opentelemetry/instrumentation-') &&
-          depName !== '@opentelemetry/instrumentation-fs'
+          depName !== '@opentelemetry/instrumentation-fs' &&
+          depName !== '@opentelemetry/instrumentation-fastify'
         );
       });