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Feature request: percentage expressed #28

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GBeattie opened this issue Aug 19, 2022 · 1 comment
Open

Feature request: percentage expressed #28

GBeattie opened this issue Aug 19, 2022 · 1 comment

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@GBeattie
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Hey, just started using this package today, very good so far!

I've noticed in the issues a few feature requests (mostly the ability to regress covariates, but also a one vs all approach analogous to FindAllMarkers, both of which I would be very interested in). I also noticed you are talking about releasing another version which may incorporate some of these suggestions.

One thing I think would be very useful, again analogous to Seurat, is to include % of cells expressing each gene by group in the output. Usefully there's a hard filter in run_de (min_features), but with the higher sensitivity of pseudobulk many of the bigger logFCs are in lowly expressed genes, so a readout such as pct.1/pct.2 would be of great utility.

Thanks for considering any of these additions!

All the best,
Gordon

@jordansquair
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Yes definitely will be a good addition to have this. Thanks Gordon!

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