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Just wanna be sure about the result. #26

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hjh-air-cond opened this issue Jul 6, 2022 · 2 comments
Open

Just wanna be sure about the result. #26

hjh-air-cond opened this issue Jul 6, 2022 · 2 comments

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@hjh-air-cond
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Thanks for make such a good work! It definately makes scRNA-seq DEGs analysis eaiser!

And there, I just wanna know for sure about the avg_logFC in the result. Is that just one of log2 or log10, or is that depending on the de_method and de_family parameters?

Thanks!

@jordansquair
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For single-cell and mixed model methods the logFC is calculated as in Seurat (log2 on tp10k). For pseudobulk methods the logFC calculated by each method (DESeq2, edgeR, limma) is provided.

@hjh-air-cond
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For single-cell and mixed model methods the logFC is calculated as in Seurat (log2 on tp10k). For pseudobulk methods the logFC calculated by each method (DESeq2, edgeR, limma) is provided.

Got That! Thanks for your reply!

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