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Genes with same adj p-val, p-val and log FC? #10

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anjkris opened this issue Mar 17, 2022 · 1 comment
Open

Genes with same adj p-val, p-val and log FC? #10

anjkris opened this issue Mar 17, 2022 · 1 comment

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@anjkris
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anjkris commented Mar 17, 2022

Thanks for your great package!

While doing some enrichment analyses with the differentially expressed genes generated from run_de with de_method = "edgeR", and de_type = "LRT", I realized that I get some genes that have exactly the same p-val, adjusted p-val and logFC (none have adj p-val < 0.05, so they're all non statistically significant). Is this normal?

@jordansquair
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Hmmm.. can you elaborate? Is it that the effect size is so small so everything is 1?

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