diff --git a/PYTHON-MANIFEST.in b/PYTHON-MANIFEST.in
index 0208a88ab14c0..02bd9b5229415 100644
--- a/PYTHON-MANIFEST.in
+++ b/PYTHON-MANIFEST.in
@@ -2,6 +2,7 @@ graft src/python/grpcio/grpc
 graft src/python/grpcio/tests
 graft src/core
 graft include/grpc
+graft third_party/boringssl
 include src/python/grpcio/commands.py
 include src/python/grpcio/grpc_core_dependencies.py
 include src/python/grpcio/README.rst
diff --git a/build.yaml b/build.yaml
index 4abef736d77b6..7ca6d525a40de 100644
--- a/build.yaml
+++ b/build.yaml
@@ -2478,3 +2478,4 @@ python_dependencies:
   deps:
   - grpc
   - gpr
+  - boringssl
diff --git a/setup.py b/setup.py
index 436db7dd46520..3d313e6936aa7 100644
--- a/setup.py
+++ b/setup.py
@@ -44,6 +44,7 @@
 
 PYTHON_STEM = './src/python/grpcio/'
 CORE_INCLUDE = ('./include', './',)
+BORINGSSL_INCLUDE = ('./third_party/boringssl/include',)
 
 # Ensure we're in the proper directory whether or not we're being used by pip.
 os.chdir(os.path.dirname(os.path.abspath(__file__)))
@@ -71,18 +72,24 @@
 
 CYTHON_EXTENSION_MODULE_NAMES = ('grpc._cython.cygrpc',)
 
-EXTENSION_INCLUDE_DIRECTORIES = (PYTHON_STEM,) + CORE_INCLUDE
+EXTENSION_INCLUDE_DIRECTORIES = (
+    (PYTHON_STEM,) + CORE_INCLUDE + BORINGSSL_INCLUDE)
 
-EXTENSION_LIBRARIES = (
-    'ssl',
-    'crypto',
-)
+EXTENSION_LIBRARIES = ()
 if not "darwin" in sys.platform:
     EXTENSION_LIBRARIES += ('rt',)
 
+EXTRA_COMPILE_ARGS = ()
+if not "win" in sys.platform:
+  EXTRA_COMPILE_ARGS = ('-pthread',)
+
+DEFINE_MACROS = (('OPENSSL_NO_ASM', 1),)
 
 def cython_extensions(package_names, module_names, include_dirs, libraries,
+                      define_macros, extra_compile_args,
                       build_with_cython=False):
+  if ENABLE_CYTHON_TRACING:
+    define_macros = define_macros + [('CYTHON_TRACE_NOGIL', 1)]
   file_extension = 'pyx' if build_with_cython else 'c'
   module_files = [os.path.join(PYTHON_STEM,
                                name.replace('.', '/') + '.' + file_extension)
@@ -92,7 +99,8 @@ def cython_extensions(package_names, module_names, include_dirs, libraries,
           name=module_name,
           sources=[module_file] + grpc_core_dependencies.CORE_SOURCE_FILES,
           include_dirs=include_dirs, libraries=libraries,
-          define_macros=[('CYTHON_TRACE_NOGIL', 1)] if ENABLE_CYTHON_TRACING else []
+          extra_compile_args=extra_compile_args,
+          define_macros=define_macros,
       ) for (module_name, module_file) in zip(module_names, module_files)
   ]
   if build_with_cython:
@@ -107,7 +115,7 @@ def cython_extensions(package_names, module_names, include_dirs, libraries,
 CYTHON_EXTENSION_MODULES = cython_extensions(
     list(CYTHON_EXTENSION_PACKAGE_NAMES), list(CYTHON_EXTENSION_MODULE_NAMES),
     list(EXTENSION_INCLUDE_DIRECTORIES), list(EXTENSION_LIBRARIES),
-    bool(BUILD_WITH_CYTHON))
+    list(DEFINE_MACROS), list(EXTRA_COMPILE_ARGS), bool(BUILD_WITH_CYTHON))
 
 PACKAGE_DIRECTORIES = {
     '': PYTHON_STEM,
diff --git a/src/python/grpcio/grpc_core_dependencies.py b/src/python/grpcio/grpc_core_dependencies.py
index cd4b7101d4396..d394c1c86e6df 100644
--- a/src/python/grpcio/grpc_core_dependencies.py
+++ b/src/python/grpcio/grpc_core_dependencies.py
@@ -192,4 +192,298 @@
   'src/core/census/initialize.c',
   'src/core/census/operation.c',
   'src/core/census/tracing.c',
+  'src/boringssl/err_data.c',
+  'third_party/boringssl/crypto/aes/aes.c',
+  'third_party/boringssl/crypto/aes/mode_wrappers.c',
+  'third_party/boringssl/crypto/asn1/a_bitstr.c',
+  'third_party/boringssl/crypto/asn1/a_bool.c',
+  'third_party/boringssl/crypto/asn1/a_bytes.c',
+  'third_party/boringssl/crypto/asn1/a_d2i_fp.c',
+  'third_party/boringssl/crypto/asn1/a_dup.c',
+  'third_party/boringssl/crypto/asn1/a_enum.c',
+  'third_party/boringssl/crypto/asn1/a_gentm.c',
+  'third_party/boringssl/crypto/asn1/a_i2d_fp.c',
+  'third_party/boringssl/crypto/asn1/a_int.c',
+  'third_party/boringssl/crypto/asn1/a_mbstr.c',
+  'third_party/boringssl/crypto/asn1/a_object.c',
+  'third_party/boringssl/crypto/asn1/a_octet.c',
+  'third_party/boringssl/crypto/asn1/a_print.c',
+  'third_party/boringssl/crypto/asn1/a_strnid.c',
+  'third_party/boringssl/crypto/asn1/a_time.c',
+  'third_party/boringssl/crypto/asn1/a_type.c',
+  'third_party/boringssl/crypto/asn1/a_utctm.c',
+  'third_party/boringssl/crypto/asn1/a_utf8.c',
+  'third_party/boringssl/crypto/asn1/asn1_lib.c',
+  'third_party/boringssl/crypto/asn1/asn1_par.c',
+  'third_party/boringssl/crypto/asn1/asn_pack.c',
+  'third_party/boringssl/crypto/asn1/bio_asn1.c',
+  'third_party/boringssl/crypto/asn1/bio_ndef.c',
+  'third_party/boringssl/crypto/asn1/f_enum.c',
+  'third_party/boringssl/crypto/asn1/f_int.c',
+  'third_party/boringssl/crypto/asn1/f_string.c',
+  'third_party/boringssl/crypto/asn1/t_bitst.c',
+  'third_party/boringssl/crypto/asn1/t_pkey.c',
+  'third_party/boringssl/crypto/asn1/tasn_dec.c',
+  'third_party/boringssl/crypto/asn1/tasn_enc.c',
+  'third_party/boringssl/crypto/asn1/tasn_fre.c',
+  'third_party/boringssl/crypto/asn1/tasn_new.c',
+  'third_party/boringssl/crypto/asn1/tasn_prn.c',
+  'third_party/boringssl/crypto/asn1/tasn_typ.c',
+  'third_party/boringssl/crypto/asn1/tasn_utl.c',
+  'third_party/boringssl/crypto/asn1/x_bignum.c',
+  'third_party/boringssl/crypto/asn1/x_long.c',
+  'third_party/boringssl/crypto/base64/base64.c',
+  'third_party/boringssl/crypto/bio/bio.c',
+  'third_party/boringssl/crypto/bio/bio_mem.c',
+  'third_party/boringssl/crypto/bio/buffer.c',
+  'third_party/boringssl/crypto/bio/connect.c',
+  'third_party/boringssl/crypto/bio/fd.c',
+  'third_party/boringssl/crypto/bio/file.c',
+  'third_party/boringssl/crypto/bio/hexdump.c',
+  'third_party/boringssl/crypto/bio/pair.c',
+  'third_party/boringssl/crypto/bio/printf.c',
+  'third_party/boringssl/crypto/bio/socket.c',
+  'third_party/boringssl/crypto/bio/socket_helper.c',
+  'third_party/boringssl/crypto/bn/add.c',
+  'third_party/boringssl/crypto/bn/asm/x86_64-gcc.c',
+  'third_party/boringssl/crypto/bn/bn.c',
+  'third_party/boringssl/crypto/bn/bn_asn1.c',
+  'third_party/boringssl/crypto/bn/cmp.c',
+  'third_party/boringssl/crypto/bn/convert.c',
+  'third_party/boringssl/crypto/bn/ctx.c',
+  'third_party/boringssl/crypto/bn/div.c',
+  'third_party/boringssl/crypto/bn/exponentiation.c',
+  'third_party/boringssl/crypto/bn/gcd.c',
+  'third_party/boringssl/crypto/bn/generic.c',
+  'third_party/boringssl/crypto/bn/kronecker.c',
+  'third_party/boringssl/crypto/bn/montgomery.c',
+  'third_party/boringssl/crypto/bn/mul.c',
+  'third_party/boringssl/crypto/bn/prime.c',
+  'third_party/boringssl/crypto/bn/random.c',
+  'third_party/boringssl/crypto/bn/rsaz_exp.c',
+  'third_party/boringssl/crypto/bn/shift.c',
+  'third_party/boringssl/crypto/bn/sqrt.c',
+  'third_party/boringssl/crypto/buf/buf.c',
+  'third_party/boringssl/crypto/bytestring/ber.c',
+  'third_party/boringssl/crypto/bytestring/cbb.c',
+  'third_party/boringssl/crypto/bytestring/cbs.c',
+  'third_party/boringssl/crypto/chacha/chacha_generic.c',
+  'third_party/boringssl/crypto/chacha/chacha_vec.c',
+  'third_party/boringssl/crypto/cipher/aead.c',
+  'third_party/boringssl/crypto/cipher/cipher.c',
+  'third_party/boringssl/crypto/cipher/derive_key.c',
+  'third_party/boringssl/crypto/cipher/e_aes.c',
+  'third_party/boringssl/crypto/cipher/e_chacha20poly1305.c',
+  'third_party/boringssl/crypto/cipher/e_des.c',
+  'third_party/boringssl/crypto/cipher/e_null.c',
+  'third_party/boringssl/crypto/cipher/e_rc2.c',
+  'third_party/boringssl/crypto/cipher/e_rc4.c',
+  'third_party/boringssl/crypto/cipher/e_ssl3.c',
+  'third_party/boringssl/crypto/cipher/e_tls.c',
+  'third_party/boringssl/crypto/cipher/tls_cbc.c',
+  'third_party/boringssl/crypto/cmac/cmac.c',
+  'third_party/boringssl/crypto/conf/conf.c',
+  'third_party/boringssl/crypto/cpu-arm.c',
+  'third_party/boringssl/crypto/cpu-intel.c',
+  'third_party/boringssl/crypto/crypto.c',
+  'third_party/boringssl/crypto/curve25519/curve25519.c',
+  'third_party/boringssl/crypto/des/des.c',
+  'third_party/boringssl/crypto/dh/check.c',
+  'third_party/boringssl/crypto/dh/dh.c',
+  'third_party/boringssl/crypto/dh/dh_asn1.c',
+  'third_party/boringssl/crypto/dh/params.c',
+  'third_party/boringssl/crypto/digest/digest.c',
+  'third_party/boringssl/crypto/digest/digests.c',
+  'third_party/boringssl/crypto/directory_posix.c',
+  'third_party/boringssl/crypto/directory_win.c',
+  'third_party/boringssl/crypto/dsa/dsa.c',
+  'third_party/boringssl/crypto/dsa/dsa_asn1.c',
+  'third_party/boringssl/crypto/ec/ec.c',
+  'third_party/boringssl/crypto/ec/ec_asn1.c',
+  'third_party/boringssl/crypto/ec/ec_key.c',
+  'third_party/boringssl/crypto/ec/ec_montgomery.c',
+  'third_party/boringssl/crypto/ec/oct.c',
+  'third_party/boringssl/crypto/ec/p224-64.c',
+  'third_party/boringssl/crypto/ec/p256-64.c',
+  'third_party/boringssl/crypto/ec/p256-x86_64.c',
+  'third_party/boringssl/crypto/ec/simple.c',
+  'third_party/boringssl/crypto/ec/util-64.c',
+  'third_party/boringssl/crypto/ec/wnaf.c',
+  'third_party/boringssl/crypto/ecdh/ecdh.c',
+  'third_party/boringssl/crypto/ecdsa/ecdsa.c',
+  'third_party/boringssl/crypto/ecdsa/ecdsa_asn1.c',
+  'third_party/boringssl/crypto/engine/engine.c',
+  'third_party/boringssl/crypto/err/err.c',
+  'third_party/boringssl/crypto/evp/algorithm.c',
+  'third_party/boringssl/crypto/evp/digestsign.c',
+  'third_party/boringssl/crypto/evp/evp.c',
+  'third_party/boringssl/crypto/evp/evp_asn1.c',
+  'third_party/boringssl/crypto/evp/evp_ctx.c',
+  'third_party/boringssl/crypto/evp/p_dsa_asn1.c',
+  'third_party/boringssl/crypto/evp/p_ec.c',
+  'third_party/boringssl/crypto/evp/p_ec_asn1.c',
+  'third_party/boringssl/crypto/evp/p_rsa.c',
+  'third_party/boringssl/crypto/evp/p_rsa_asn1.c',
+  'third_party/boringssl/crypto/evp/pbkdf.c',
+  'third_party/boringssl/crypto/evp/sign.c',
+  'third_party/boringssl/crypto/ex_data.c',
+  'third_party/boringssl/crypto/hkdf/hkdf.c',
+  'third_party/boringssl/crypto/hmac/hmac.c',
+  'third_party/boringssl/crypto/lhash/lhash.c',
+  'third_party/boringssl/crypto/md4/md4.c',
+  'third_party/boringssl/crypto/md5/md5.c',
+  'third_party/boringssl/crypto/mem.c',
+  'third_party/boringssl/crypto/modes/cbc.c',
+  'third_party/boringssl/crypto/modes/cfb.c',
+  'third_party/boringssl/crypto/modes/ctr.c',
+  'third_party/boringssl/crypto/modes/gcm.c',
+  'third_party/boringssl/crypto/modes/ofb.c',
+  'third_party/boringssl/crypto/obj/obj.c',
+  'third_party/boringssl/crypto/obj/obj_xref.c',
+  'third_party/boringssl/crypto/pem/pem_all.c',
+  'third_party/boringssl/crypto/pem/pem_info.c',
+  'third_party/boringssl/crypto/pem/pem_lib.c',
+  'third_party/boringssl/crypto/pem/pem_oth.c',
+  'third_party/boringssl/crypto/pem/pem_pk8.c',
+  'third_party/boringssl/crypto/pem/pem_pkey.c',
+  'third_party/boringssl/crypto/pem/pem_x509.c',
+  'third_party/boringssl/crypto/pem/pem_xaux.c',
+  'third_party/boringssl/crypto/pkcs8/p5_pbe.c',
+  'third_party/boringssl/crypto/pkcs8/p5_pbev2.c',
+  'third_party/boringssl/crypto/pkcs8/p8_pkey.c',
+  'third_party/boringssl/crypto/pkcs8/pkcs8.c',
+  'third_party/boringssl/crypto/poly1305/poly1305.c',
+  'third_party/boringssl/crypto/poly1305/poly1305_arm.c',
+  'third_party/boringssl/crypto/poly1305/poly1305_vec.c',
+  'third_party/boringssl/crypto/rand/rand.c',
+  'third_party/boringssl/crypto/rand/urandom.c',
+  'third_party/boringssl/crypto/rand/windows.c',
+  'third_party/boringssl/crypto/rc4/rc4.c',
+  'third_party/boringssl/crypto/refcount_c11.c',
+  'third_party/boringssl/crypto/refcount_lock.c',
+  'third_party/boringssl/crypto/rsa/blinding.c',
+  'third_party/boringssl/crypto/rsa/padding.c',
+  'third_party/boringssl/crypto/rsa/rsa.c',
+  'third_party/boringssl/crypto/rsa/rsa_asn1.c',
+  'third_party/boringssl/crypto/rsa/rsa_impl.c',
+  'third_party/boringssl/crypto/sha/sha1.c',
+  'third_party/boringssl/crypto/sha/sha256.c',
+  'third_party/boringssl/crypto/sha/sha512.c',
+  'third_party/boringssl/crypto/stack/stack.c',
+  'third_party/boringssl/crypto/thread.c',
+  'third_party/boringssl/crypto/thread_none.c',
+  'third_party/boringssl/crypto/thread_pthread.c',
+  'third_party/boringssl/crypto/thread_win.c',
+  'third_party/boringssl/crypto/time_support.c',
+  'third_party/boringssl/crypto/x509/a_digest.c',
+  'third_party/boringssl/crypto/x509/a_sign.c',
+  'third_party/boringssl/crypto/x509/a_strex.c',
+  'third_party/boringssl/crypto/x509/a_verify.c',
+  'third_party/boringssl/crypto/x509/asn1_gen.c',
+  'third_party/boringssl/crypto/x509/by_dir.c',
+  'third_party/boringssl/crypto/x509/by_file.c',
+  'third_party/boringssl/crypto/x509/i2d_pr.c',
+  'third_party/boringssl/crypto/x509/pkcs7.c',
+  'third_party/boringssl/crypto/x509/t_crl.c',
+  'third_party/boringssl/crypto/x509/t_req.c',
+  'third_party/boringssl/crypto/x509/t_x509.c',
+  'third_party/boringssl/crypto/x509/t_x509a.c',
+  'third_party/boringssl/crypto/x509/x509.c',
+  'third_party/boringssl/crypto/x509/x509_att.c',
+  'third_party/boringssl/crypto/x509/x509_cmp.c',
+  'third_party/boringssl/crypto/x509/x509_d2.c',
+  'third_party/boringssl/crypto/x509/x509_def.c',
+  'third_party/boringssl/crypto/x509/x509_ext.c',
+  'third_party/boringssl/crypto/x509/x509_lu.c',
+  'third_party/boringssl/crypto/x509/x509_obj.c',
+  'third_party/boringssl/crypto/x509/x509_r2x.c',
+  'third_party/boringssl/crypto/x509/x509_req.c',
+  'third_party/boringssl/crypto/x509/x509_set.c',
+  'third_party/boringssl/crypto/x509/x509_trs.c',
+  'third_party/boringssl/crypto/x509/x509_txt.c',
+  'third_party/boringssl/crypto/x509/x509_v3.c',
+  'third_party/boringssl/crypto/x509/x509_vfy.c',
+  'third_party/boringssl/crypto/x509/x509_vpm.c',
+  'third_party/boringssl/crypto/x509/x509cset.c',
+  'third_party/boringssl/crypto/x509/x509name.c',
+  'third_party/boringssl/crypto/x509/x509rset.c',
+  'third_party/boringssl/crypto/x509/x509spki.c',
+  'third_party/boringssl/crypto/x509/x509type.c',
+  'third_party/boringssl/crypto/x509/x_algor.c',
+  'third_party/boringssl/crypto/x509/x_all.c',
+  'third_party/boringssl/crypto/x509/x_attrib.c',
+  'third_party/boringssl/crypto/x509/x_crl.c',
+  'third_party/boringssl/crypto/x509/x_exten.c',
+  'third_party/boringssl/crypto/x509/x_info.c',
+  'third_party/boringssl/crypto/x509/x_name.c',
+  'third_party/boringssl/crypto/x509/x_pkey.c',
+  'third_party/boringssl/crypto/x509/x_pubkey.c',
+  'third_party/boringssl/crypto/x509/x_req.c',
+  'third_party/boringssl/crypto/x509/x_sig.c',
+  'third_party/boringssl/crypto/x509/x_spki.c',
+  'third_party/boringssl/crypto/x509/x_val.c',
+  'third_party/boringssl/crypto/x509/x_x509.c',
+  'third_party/boringssl/crypto/x509/x_x509a.c',
+  'third_party/boringssl/crypto/x509v3/pcy_cache.c',
+  'third_party/boringssl/crypto/x509v3/pcy_data.c',
+  'third_party/boringssl/crypto/x509v3/pcy_lib.c',
+  'third_party/boringssl/crypto/x509v3/pcy_map.c',
+  'third_party/boringssl/crypto/x509v3/pcy_node.c',
+  'third_party/boringssl/crypto/x509v3/pcy_tree.c',
+  'third_party/boringssl/crypto/x509v3/v3_akey.c',
+  'third_party/boringssl/crypto/x509v3/v3_akeya.c',
+  'third_party/boringssl/crypto/x509v3/v3_alt.c',
+  'third_party/boringssl/crypto/x509v3/v3_bcons.c',
+  'third_party/boringssl/crypto/x509v3/v3_bitst.c',
+  'third_party/boringssl/crypto/x509v3/v3_conf.c',
+  'third_party/boringssl/crypto/x509v3/v3_cpols.c',
+  'third_party/boringssl/crypto/x509v3/v3_crld.c',
+  'third_party/boringssl/crypto/x509v3/v3_enum.c',
+  'third_party/boringssl/crypto/x509v3/v3_extku.c',
+  'third_party/boringssl/crypto/x509v3/v3_genn.c',
+  'third_party/boringssl/crypto/x509v3/v3_ia5.c',
+  'third_party/boringssl/crypto/x509v3/v3_info.c',
+  'third_party/boringssl/crypto/x509v3/v3_int.c',
+  'third_party/boringssl/crypto/x509v3/v3_lib.c',
+  'third_party/boringssl/crypto/x509v3/v3_ncons.c',
+  'third_party/boringssl/crypto/x509v3/v3_pci.c',
+  'third_party/boringssl/crypto/x509v3/v3_pcia.c',
+  'third_party/boringssl/crypto/x509v3/v3_pcons.c',
+  'third_party/boringssl/crypto/x509v3/v3_pku.c',
+  'third_party/boringssl/crypto/x509v3/v3_pmaps.c',
+  'third_party/boringssl/crypto/x509v3/v3_prn.c',
+  'third_party/boringssl/crypto/x509v3/v3_purp.c',
+  'third_party/boringssl/crypto/x509v3/v3_skey.c',
+  'third_party/boringssl/crypto/x509v3/v3_sxnet.c',
+  'third_party/boringssl/crypto/x509v3/v3_utl.c',
+  'third_party/boringssl/ssl/custom_extensions.c',
+  'third_party/boringssl/ssl/d1_both.c',
+  'third_party/boringssl/ssl/d1_clnt.c',
+  'third_party/boringssl/ssl/d1_lib.c',
+  'third_party/boringssl/ssl/d1_meth.c',
+  'third_party/boringssl/ssl/d1_pkt.c',
+  'third_party/boringssl/ssl/d1_srtp.c',
+  'third_party/boringssl/ssl/d1_srvr.c',
+  'third_party/boringssl/ssl/dtls_record.c',
+  'third_party/boringssl/ssl/pqueue/pqueue.c',
+  'third_party/boringssl/ssl/s3_both.c',
+  'third_party/boringssl/ssl/s3_clnt.c',
+  'third_party/boringssl/ssl/s3_enc.c',
+  'third_party/boringssl/ssl/s3_lib.c',
+  'third_party/boringssl/ssl/s3_meth.c',
+  'third_party/boringssl/ssl/s3_pkt.c',
+  'third_party/boringssl/ssl/s3_srvr.c',
+  'third_party/boringssl/ssl/ssl_aead_ctx.c',
+  'third_party/boringssl/ssl/ssl_asn1.c',
+  'third_party/boringssl/ssl/ssl_buffer.c',
+  'third_party/boringssl/ssl/ssl_cert.c',
+  'third_party/boringssl/ssl/ssl_cipher.c',
+  'third_party/boringssl/ssl/ssl_file.c',
+  'third_party/boringssl/ssl/ssl_lib.c',
+  'third_party/boringssl/ssl/ssl_rsa.c',
+  'third_party/boringssl/ssl/ssl_session.c',
+  'third_party/boringssl/ssl/ssl_stat.c',
+  'third_party/boringssl/ssl/t1_enc.c',
+  'third_party/boringssl/ssl/t1_lib.c',
+  'third_party/boringssl/ssl/tls_record.c',
 ]
diff --git a/tools/run_tests/build_python.sh b/tools/run_tests/build_python.sh
index 8159e5a464fe0..80b0088579c36 100755
--- a/tools/run_tests/build_python.sh
+++ b/tools/run_tests/build_python.sh
@@ -37,8 +37,8 @@ ROOT=`pwd`
 export LD_LIBRARY_PATH=$ROOT/libs/$CONFIG
 export DYLD_LIBRARY_PATH=$ROOT/libs/$CONFIG
 export PATH=$ROOT/bins/$CONFIG:$ROOT/bins/$CONFIG/protobuf:$PATH
-export CFLAGS="-I$ROOT/include -std=c89"
-export LDFLAGS="-L$ROOT/libs/$CONFIG -L$ROOT/libs/$CONFIG/openssl"
+export CFLAGS="-I$ROOT/include -std=gnu99"
+export LDFLAGS="-L$ROOT/libs/$CONFIG"
 export GRPC_PYTHON_BUILD_WITH_CYTHON=1
 export GRPC_PYTHON_ENABLE_CYTHON_TRACING=1
 
diff --git a/tools/run_tests/run_python.sh b/tools/run_tests/run_python.sh
index 3514492646017..23f2122905ab5 100755
--- a/tools/run_tests/run_python.sh
+++ b/tools/run_tests/run_python.sh
@@ -38,7 +38,7 @@ export LD_LIBRARY_PATH=$ROOT/libs/$CONFIG
 export DYLD_LIBRARY_PATH=$ROOT/libs/$CONFIG
 export PATH=$ROOT/bins/$CONFIG:$ROOT/bins/$CONFIG/protobuf:$PATH
 export CFLAGS="-I$ROOT/include -std=c89"
-export LDFLAGS="-L$ROOT/libs/$CONFIG -L$ROOT/libs/$CONFIG/openssl"
+export LDFLAGS="-L$ROOT/libs/$CONFIG"
 export GRPC_PYTHON_BUILD_WITH_CYTHON=1
 export GRPC_PYTHON_ENABLE_CYTHON_TRACING=1