In the Python SDK, the setup_observability() path does not take advantage of the Azure Monitor OTel distro's configure_azure_monitor call to wire up Application Insights, instead relying on creating the exporters manually. As such, it doesn't have the enable_live_metrics functionality, and so Live Metric (QuickPulse) telemetry is not emitted which breaks important functionality. It'd be great to get all the Agent insights without losing Live Metrics.
I've not yet found a workaround for this, but am continuing to hack away at it.