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The relationship between cell type association and heterogeneity #99

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AI-10 opened this issue Aug 18, 2024 · 1 comment

AI-10 commented Aug 18, 2024 •

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hi, thanks for this powerful tool！

I did some analyses and have some questions about the interpretation of the results.

Is the discussion of within-cell type heterogeneity premised on that the cell type is significantly associated with the trait?

I found some cell types that were significantly associated with MDD, but the heterogeneity was significant for some other cell types.

Owner

martinjzhang commented Oct 30, 2024

Sorry I missed this. Yes, that's how we generated figure 3 in the original paper. We think the signals are more robust this way.

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