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DESCRIPTION
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DESCRIPTION
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Package: echoseq
Type: Package
Title: Replication and Simulation of Genetic Variants, Molecular Expression
Levels and Other Phenotypic Data
Version: 0.3.2
Date: 2021-01-20
Authors@R: c(
person("Helene", "Ruffieux", email = "[email protected]",
role = c("aut", "cre")))
Description: This package provides functions to emulate molecular quantitative
trait locus data and clinical data associated with genetic variants under
user-specified association patterns. The data can be the result of pure
simulation or can replicate real datasets supplied by the user (which may
replace real data when these cannot be shared for diverse privacy reasons).
The data generation schemes are based on generally accepted principles of
population genetics (Hardy--Weinberg equilibrium, linkage-disequilibrium,
natural selection, pleiotropic control, sparsity assumptions, epigenetic
control, etc.).
Depends:
R (>= 3.2.0)
License: GPL (>= 3) | file LICENSE
LazyData: TRUE
Imports:
dplyr (>= 0.8.4),
extraDistr (>= 1.8.11),
Matrix (>= 1.2-2),
parallel,
plyr (>= 1.8.4),
rlang (>= 0.4.5)
RoxygenNote: 7.1.1
Suggests: testthat
Encoding: UTF-8