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diff.Methy in callDMR #37

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BeatrizFaustino opened this issue Jun 15, 2023 · 3 comments
Open

diff.Methy in callDMR #37

BeatrizFaustino opened this issue Jun 15, 2023 · 3 comments

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@BeatrizFaustino
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I would like to better understand what diff.Methy is, how is that data represented, whether in percentage or otherwise?
@haowulab
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It's the mean methylation difference (in percentage) between two groups. This column only appears in two-group comparison case.

@BeatrizFaustino
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Thank you for the answer. Please help me with another question, how can I see if the regions present in the call_DMR.txt table are hypomethylated or hypermethylated? I'm starting this study now and I couldn't understand! Thank you very much in advance

@haowulab
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hyper- or hypo-methylation can be determined by the sign of diff.Methy. Note, this only works for two-group comparison.

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@haowulab @BeatrizFaustino