diff --git a/.github/workflows/esy.yml b/.github/workflows/esy.yml
index 1120f9a..c7ee222 100644
--- a/.github/workflows/esy.yml
+++ b/.github/workflows/esy.yml
@@ -17,7 +17,7 @@ jobs:
       - name: Setup node.js
         uses: actions/setup-node@cdca7365b2dadb8aad0a33bc7601856ffabcc48e # v4.3.0
         with:
-          node-version: "16"
+          node-version: "22"
           check-latest: true
 
       # Install `esy` to build the project
diff --git a/.github/workflows/js.yml b/.github/workflows/js.yml
index 569929b..189d7e9 100644
--- a/.github/workflows/js.yml
+++ b/.github/workflows/js.yml
@@ -13,7 +13,7 @@ jobs:
       - name: Setup node.js
         uses: actions/setup-node@cdca7365b2dadb8aad0a33bc7601856ffabcc48e # v4.3.0
         with:
-          node-version: "16"
+          node-version: "22"
           check-latest: true
 
       - name: "Set up emsdk"
diff --git a/.github/workflows/opam.yml b/.github/workflows/opam.yml
index 3b0baf9..0eb8d8a 100644
--- a/.github/workflows/opam.yml
+++ b/.github/workflows/opam.yml
@@ -15,6 +15,12 @@ jobs:
         ocaml-compiler: [4.13.1, 4.14.1, 5.3.0]
 
     steps:
+      - name: Setup node.js
+        uses: actions/setup-node@cdca7365b2dadb8aad0a33bc7601856ffabcc48e # v4.3.0
+        with:
+          node-version: "22"
+          check-latest: true
+
       - name: Checkout project
         uses: actions/checkout@11bd71901bbe5b1630ceea73d27597364c9af683 # v4.2.2
         with:
diff --git a/.github/workflows/release.yml b/.github/workflows/release.yml
index df52996..4314be3 100644
--- a/.github/workflows/release.yml
+++ b/.github/workflows/release.yml
@@ -102,7 +102,7 @@ jobs:
       - name: Setup NodeJS
         uses: actions/setup-node@cdca7365b2dadb8aad0a33bc7601856ffabcc48e # v4.3.0
         with:
-          node-version: "16"
+          node-version: "22"
           registry-url: "https://registry.npmjs.org"
 
       - name: Publish to npm
diff --git a/esy.lock/index.json b/esy.lock/index.json
index a026379..0534751 100644
--- a/esy.lock/index.json
+++ b/esy.lock/index.json
@@ -1,5 +1,5 @@
 {
-  "checksum": "8096f1a43ac441e386d8e73c0addbe20",
+  "checksum": "0788e0bc808e13adda49a6a958abdf76",
   "root": "@grain/libbinaryen@link-dev:./package.json",
   "node": {
     "ocaml@5.2.0@d41d8cd9": {
@@ -240,8 +240,8 @@
       ],
       "available": "true"
     },
-    "@opam/stdio@opam:v0.17.0@29b17754": {
-      "id": "@opam/stdio@opam:v0.17.0@29b17754",
+    "@opam/stdio@opam:v0.17.0@def6a62f": {
+      "id": "@opam/stdio@opam:v0.17.0@def6a62f",
       "name": "@opam/stdio",
       "version": "opam:v0.17.0",
       "source": {
@@ -259,14 +259,14 @@
       "overrides": [],
       "dependencies": [
         "ocaml@5.2.0@d41d8cd9", "@opam/dune@opam:3.17.2@31dc7e86",
-        "@opam/base@opam:v0.17.1@699decbd",
+        "@opam/base@opam:v0.17.1@6229f0ef",
         "@esy-ocaml/substs@0.0.1@d41d8cd9"
       ],
       "devDependencies": [
         "ocaml@5.2.0@d41d8cd9", "@opam/dune@opam:3.17.2@31dc7e86",
-        "@opam/base@opam:v0.17.1@699decbd"
+        "@opam/base@opam:v0.17.1@6229f0ef"
       ],
-      "available": "arch != \"arm32\" & arch != \"x86_32\""
+      "available": "arch != \"x86_32\""
     },
     "@opam/spawn@opam:v0.17.0@d0f69739": {
       "id": "@opam/spawn@opam:v0.17.0@d0f69739",
@@ -294,8 +294,8 @@
       ],
       "available": "os != \"freebsd\""
     },
-    "@opam/sexplib0@opam:v0.17.0@21847769": {
-      "id": "@opam/sexplib0@opam:v0.17.0@21847769",
+    "@opam/sexplib0@opam:v0.17.0@75dcb697": {
+      "id": "@opam/sexplib0@opam:v0.17.0@75dcb697",
       "name": "@opam/sexplib0",
       "version": "opam:v0.17.0",
       "source": {
@@ -318,7 +318,7 @@
       "devDependencies": [
         "ocaml@5.2.0@d41d8cd9", "@opam/dune@opam:3.17.2@31dc7e86"
       ],
-      "available": "arch != \"arm32\" & arch != \"x86_32\""
+      "available": "arch != \"x86_32\""
     },
     "@opam/seq@opam:base@5ed5af70": {
       "id": "@opam/seq@opam:base@5ed5af70",
@@ -426,14 +426,14 @@
       "overrides": [],
       "dependencies": [
         "ocaml@5.2.0@d41d8cd9", "@opam/stdlib-shims@opam:0.3.0@72c7bc98",
-        "@opam/sexplib0@opam:v0.17.0@21847769",
+        "@opam/sexplib0@opam:v0.17.0@75dcb697",
         "@opam/ppx_derivers@opam:1.2.1@d78727cd",
         "@opam/ocaml-compiler-libs@opam:v0.17.0@6bdcfede",
         "@opam/dune@opam:3.17.2@31dc7e86", "@esy-ocaml/substs@0.0.1@d41d8cd9"
       ],
       "devDependencies": [
         "ocaml@5.2.0@d41d8cd9", "@opam/stdlib-shims@opam:0.3.0@72c7bc98",
-        "@opam/sexplib0@opam:v0.17.0@21847769",
+        "@opam/sexplib0@opam:v0.17.0@75dcb697",
         "@opam/ppx_derivers@opam:1.2.1@d78727cd",
         "@opam/ocaml-compiler-libs@opam:v0.17.0@6bdcfede",
         "@opam/dune@opam:3.17.2@31dc7e86"
@@ -624,7 +624,7 @@
       "dependencies": [
         "ocaml@5.2.0@d41d8cd9", "@opam/uutf@opam:1.0.4@ba7fbef7",
         "@opam/uuseg@opam:16.0.0@bd0df457",
-        "@opam/stdio@opam:v0.17.0@29b17754",
+        "@opam/stdio@opam:v0.17.0@def6a62f",
         "@opam/ocp-indent@opam:1.7.0@3e255333",
         "@opam/ocaml-version@opam:4.0.0@db2acb74",
         "@opam/menhirSdk@opam:20240715@9d924351",
@@ -637,14 +637,14 @@
         "@opam/dune@opam:3.17.2@31dc7e86", "@opam/csexp@opam:1.5.2@46614bf4",
         "@opam/cmdliner@opam:1.3.0@8e6dd99f",
         "@opam/camlp-streams@opam:5.0.1@8e96208c",
-        "@opam/base@opam:v0.17.1@699decbd",
+        "@opam/base@opam:v0.17.1@6229f0ef",
         "@opam/astring@opam:0.8.5@9975798d",
         "@esy-ocaml/substs@0.0.1@d41d8cd9"
       ],
       "devDependencies": [
         "ocaml@5.2.0@d41d8cd9", "@opam/uutf@opam:1.0.4@ba7fbef7",
         "@opam/uuseg@opam:16.0.0@bd0df457",
-        "@opam/stdio@opam:v0.17.0@29b17754",
+        "@opam/stdio@opam:v0.17.0@def6a62f",
         "@opam/ocp-indent@opam:1.7.0@3e255333",
         "@opam/ocaml-version@opam:4.0.0@db2acb74",
         "@opam/menhirSdk@opam:20240715@9d924351",
@@ -657,7 +657,7 @@
         "@opam/dune@opam:3.17.2@31dc7e86", "@opam/csexp@opam:1.5.2@46614bf4",
         "@opam/cmdliner@opam:1.3.0@8e6dd99f",
         "@opam/camlp-streams@opam:5.0.1@8e96208c",
-        "@opam/base@opam:v0.17.1@699decbd",
+        "@opam/base@opam:v0.17.1@6229f0ef",
         "@opam/astring@opam:0.8.5@9975798d"
       ],
       "available": "true"
@@ -771,8 +771,8 @@
       "devDependencies": [ "ocaml@5.2.0@d41d8cd9" ],
       "available": "true"
     },
-    "@opam/ocaml_intrinsics_kernel@opam:v0.17.1@ea7fa575": {
-      "id": "@opam/ocaml_intrinsics_kernel@opam:v0.17.1@ea7fa575",
+    "@opam/ocaml_intrinsics_kernel@opam:v0.17.1@122c1c73": {
+      "id": "@opam/ocaml_intrinsics_kernel@opam:v0.17.1@122c1c73",
       "name": "@opam/ocaml_intrinsics_kernel",
       "version": "opam:v0.17.1",
       "source": {
@@ -795,7 +795,7 @@
       "devDependencies": [
         "ocaml@5.2.0@d41d8cd9", "@opam/dune@opam:3.17.2@31dc7e86"
       ],
-      "available": "arch != \"arm32\" & arch != \"x86_32\""
+      "available": "arch != \"x86_32\""
     },
     "@opam/ocaml-version@opam:4.0.0@db2acb74": {
       "id": "@opam/ocaml-version@opam:4.0.0@db2acb74",
@@ -859,7 +859,7 @@
         "@opam/dune@opam:3.17.2@31dc7e86", "@opam/csexp@opam:1.5.2@46614bf4",
         "@opam/chrome-trace@opam:3.17.2@ece6ea1d",
         "@opam/camlp-streams@opam:5.0.1@8e96208c",
-        "@opam/base@opam:v0.17.1@699decbd",
+        "@opam/base@opam:v0.17.1@6229f0ef",
         "@opam/astring@opam:0.8.5@9975798d",
         "@esy-ocaml/substs@0.0.1@d41d8cd9"
       ],
@@ -882,7 +882,7 @@
         "@opam/dune@opam:3.17.2@31dc7e86", "@opam/csexp@opam:1.5.2@46614bf4",
         "@opam/chrome-trace@opam:3.17.2@ece6ea1d",
         "@opam/camlp-streams@opam:5.0.1@8e96208c",
-        "@opam/base@opam:v0.17.1@699decbd",
+        "@opam/base@opam:v0.17.1@6229f0ef",
         "@opam/astring@opam:0.8.5@9975798d"
       ],
       "available": "true"
@@ -1108,20 +1108,20 @@
       ],
       "available": "true"
     },
-    "@opam/js_of_ocaml-compiler@opam:5.9.1@e8650b39": {
-      "id": "@opam/js_of_ocaml-compiler@opam:5.9.1@e8650b39",
+    "@opam/js_of_ocaml-compiler@opam:6.0.1@ac2ae2e8": {
+      "id": "@opam/js_of_ocaml-compiler@opam:6.0.1@ac2ae2e8",
       "name": "@opam/js_of_ocaml-compiler",
-      "version": "opam:5.9.1",
+      "version": "opam:6.0.1",
       "source": {
         "type": "install",
         "source": [
-          "archive:https://opam.ocaml.org/cache/sha256/68/68c95c60871d8e9c9a54c82f35e2ed50413bcb440f220d0b3516b2a1ee1c7307#sha256:68c95c60871d8e9c9a54c82f35e2ed50413bcb440f220d0b3516b2a1ee1c7307",
-          "archive:https://github.com/ocsigen/js_of_ocaml/releases/download/5.9.1/js_of_ocaml-5.9.1.tbz#sha256:68c95c60871d8e9c9a54c82f35e2ed50413bcb440f220d0b3516b2a1ee1c7307"
+          "archive:https://opam.ocaml.org/cache/sha256/81/813dbee2b62e1541049ea23a20e405cf244e27ebfa9859785cfa53e286d2c614#sha256:813dbee2b62e1541049ea23a20e405cf244e27ebfa9859785cfa53e286d2c614",
+          "archive:https://github.com/ocsigen/js_of_ocaml/releases/download/6.0.1/js_of_ocaml-6.0.1.tbz#sha256:813dbee2b62e1541049ea23a20e405cf244e27ebfa9859785cfa53e286d2c614"
         ],
         "opam": {
           "name": "js_of_ocaml-compiler",
-          "version": "5.9.1",
-          "path": "esy.lock/opam/js_of_ocaml-compiler.5.9.1"
+          "version": "6.0.1",
+          "path": "esy.lock/opam/js_of_ocaml-compiler.6.0.1"
         }
       },
       "overrides": [],
@@ -1605,8 +1605,8 @@
       ],
       "available": "true"
     },
-    "@opam/base@opam:v0.17.1@699decbd": {
-      "id": "@opam/base@opam:v0.17.1@699decbd",
+    "@opam/base@opam:v0.17.1@6229f0ef": {
+      "id": "@opam/base@opam:v0.17.1@6229f0ef",
       "name": "@opam/base",
       "version": "opam:v0.17.1",
       "source": {
@@ -1623,18 +1623,18 @@
       },
       "overrides": [],
       "dependencies": [
-        "ocaml@5.2.0@d41d8cd9", "@opam/sexplib0@opam:v0.17.0@21847769",
-        "@opam/ocaml_intrinsics_kernel@opam:v0.17.1@ea7fa575",
+        "ocaml@5.2.0@d41d8cd9", "@opam/sexplib0@opam:v0.17.0@75dcb697",
+        "@opam/ocaml_intrinsics_kernel@opam:v0.17.1@122c1c73",
         "@opam/dune-configurator@opam:3.17.2@6a903a8c",
         "@opam/dune@opam:3.17.2@31dc7e86", "@esy-ocaml/substs@0.0.1@d41d8cd9"
       ],
       "devDependencies": [
-        "ocaml@5.2.0@d41d8cd9", "@opam/sexplib0@opam:v0.17.0@21847769",
-        "@opam/ocaml_intrinsics_kernel@opam:v0.17.1@ea7fa575",
+        "ocaml@5.2.0@d41d8cd9", "@opam/sexplib0@opam:v0.17.0@75dcb697",
+        "@opam/ocaml_intrinsics_kernel@opam:v0.17.1@122c1c73",
         "@opam/dune-configurator@opam:3.17.2@6a903a8c",
         "@opam/dune@opam:3.17.2@31dc7e86"
       ],
-      "available": "arch != \"arm32\" & arch != \"x86_32\""
+      "available": "arch != \"x86_32\""
     },
     "@opam/astring@opam:0.8.5@9975798d": {
       "id": "@opam/astring@opam:0.8.5@9975798d",
@@ -1681,7 +1681,7 @@
       "devDependencies": [
         "@opam/ocamlformat@opam:0.27.0@6c2dc1c8",
         "@opam/ocaml-lsp-server@opam:1.21.0@3b310a8b",
-        "@opam/js_of_ocaml-compiler@opam:5.9.1@e8650b39"
+        "@opam/js_of_ocaml-compiler@opam:6.0.1@ac2ae2e8"
       ]
     },
     "@esy-ocaml/substs@0.0.1@d41d8cd9": {
diff --git a/esy.lock/opam/base.v0.17.1/opam b/esy.lock/opam/base.v0.17.1/opam
index faba069..40b59f0 100644
--- a/esy.lock/opam/base.v0.17.1/opam
+++ b/esy.lock/opam/base.v0.17.1/opam
@@ -16,7 +16,7 @@ depends: [
   "dune"                    {>= "3.11.0"}
   "dune-configurator"
 ]
-available: arch != "arm32" & arch != "x86_32"
+available: arch != "x86_32"
 synopsis: "Full standard library replacement for OCaml"
 description: "
 Full standard library replacement for OCaml
diff --git a/esy.lock/opam/js_of_ocaml-compiler.5.9.1/opam b/esy.lock/opam/js_of_ocaml-compiler.6.0.1/opam
similarity index 72%
rename from esy.lock/opam/js_of_ocaml-compiler.5.9.1/opam
rename to esy.lock/opam/js_of_ocaml-compiler.6.0.1/opam
index 89af4b1..ed835fe 100644
--- a/esy.lock/opam/js_of_ocaml-compiler.5.9.1/opam
+++ b/esy.lock/opam/js_of_ocaml-compiler.6.0.1/opam
@@ -11,10 +11,10 @@ homepage: "https://ocsigen.org/js_of_ocaml/latest/manual/overview"
 doc: "https://ocsigen.org/js_of_ocaml/latest/manual/overview"
 bug-reports: "https://github.com/ocsigen/js_of_ocaml/issues"
 depends: [
-  "dune" {>= "3.15"}
+  "dune" {>= "3.17"}
   "ocaml" {>= "4.08" & < "5.4"}
   "num" {with-test}
-  "ppx_expect" {>= "v0.14.2" & with-test}
+  "ppx_expect" {>= "v0.16.1" & with-test}
   "ppxlib" {>= "0.15.0" & < "0.36.0"}
   "re" {with-test}
   "cmdliner" {>= "1.1.0"}
@@ -23,7 +23,7 @@ depends: [
   "menhir"
   "menhirLib"
   "menhirSdk"
-  "yojson" {>= "1.6"}
+  "yojson" {>= "2.1"}
   "odoc" {with-doc}
 ]
 depopts: ["ocamlfind"]
@@ -47,10 +47,10 @@ build: [
 ]
 url {
   src:
-    "https://github.com/ocsigen/js_of_ocaml/releases/download/5.9.1/js_of_ocaml-5.9.1.tbz"
+    "https://github.com/ocsigen/js_of_ocaml/releases/download/6.0.1/js_of_ocaml-6.0.1.tbz"
   checksum: [
-    "sha256=68c95c60871d8e9c9a54c82f35e2ed50413bcb440f220d0b3516b2a1ee1c7307"
-    "sha512=288d68ea7a45e92375cf51c34bb1071dd26d0d8de54883f3422639561e1494ff43aa45c3d7466627fd7b5a9bb29a0c75e5744a3e7147f5d544bf2c5414083778"
+    "sha256=813dbee2b62e1541049ea23a20e405cf244e27ebfa9859785cfa53e286d2c614"
+    "sha512=194ae5d1122171fa8253b6a41438a2fc330caf4ab6dd008fcce1253fd51fbe4b1149813da6075c5deb52ea136143def57c83c3f4e32421803d7699648fdc563b"
   ]
 }
-x-commit-hash: "a02342914f3221a298730d61537cc0d939ccb6e0"
+x-commit-hash: "b6d60e4f8ff35e7c7b3bb52b97ffedc3eb8e3d08"
diff --git a/esy.lock/opam/ocaml_intrinsics_kernel.v0.17.1/opam b/esy.lock/opam/ocaml_intrinsics_kernel.v0.17.1/opam
index e4cd8e9..44be913 100644
--- a/esy.lock/opam/ocaml_intrinsics_kernel.v0.17.1/opam
+++ b/esy.lock/opam/ocaml_intrinsics_kernel.v0.17.1/opam
@@ -13,7 +13,7 @@ depends: [
   "ocaml" {>= "5.1.0"}
   "dune" {>= "3.11.0"}
 ]
-available: arch != "arm32" & arch != "x86_32"
+available: arch != "x86_32"
 synopsis: "Intrinsics"
 description: "
 Provides functions to invoke amd64 instructions (such as cmov, min/maxsd, popcnt)
diff --git a/esy.lock/opam/sexplib0.v0.17.0/opam b/esy.lock/opam/sexplib0.v0.17.0/opam
index 4a8cdc5..7cd4cf8 100644
--- a/esy.lock/opam/sexplib0.v0.17.0/opam
+++ b/esy.lock/opam/sexplib0.v0.17.0/opam
@@ -13,7 +13,7 @@ depends: [
   "ocaml" {>= "4.14.0"}
   "dune" {>= "3.11.0"}
 ]
-available: arch != "arm32" & arch != "x86_32"
+available: arch != "x86_32"
 synopsis: "Library containing the definition of S-expressions and some base converters"
 description: "
 Part of Jane Street's Core library
diff --git a/esy.lock/opam/stdio.v0.17.0/opam b/esy.lock/opam/stdio.v0.17.0/opam
index daecaa2..6939fc7 100644
--- a/esy.lock/opam/stdio.v0.17.0/opam
+++ b/esy.lock/opam/stdio.v0.17.0/opam
@@ -14,7 +14,7 @@ depends: [
   "base"  {>= "v0.17" & < "v0.18"}
   "dune"  {>= "3.11.0"}
 ]
-available: arch != "arm32" & arch != "x86_32"
+available: arch != "x86_32"
 synopsis: "Standard IO library for OCaml"
 description: "
 Stdio implements simple input/output functionalities for OCaml.
diff --git a/libbinaryen.opam b/libbinaryen.opam
index c67bba8..d98e04b 100644
--- a/libbinaryen.opam
+++ b/libbinaryen.opam
@@ -15,7 +15,7 @@ depends: [
   "conf-cmake" {build}
   "dune" {>= "3.0.0"}
   "dune-configurator" {>= "3.0.0"}
-  "js_of_ocaml-compiler" {with-test & >= "4.1.0" < "6.0.0"}
+  "js_of_ocaml-compiler" {with-test & >= "4.1.0" < "7.0.0"}
   "ocaml" {>= "4.13"}
 ]
 depexts: [
diff --git a/package.json b/package.json
index 4c9ba95..3a5309b 100644
--- a/package.json
+++ b/package.json
@@ -11,7 +11,7 @@
     "@opam/dune-configurator": ">= 3.0.0"
   },
   "devDependencies": {
-    "@opam/js_of_ocaml-compiler": ">= 4.1.0 < 6.0.0",
+    "@opam/js_of_ocaml-compiler": ">= 4.1.0 < 7.0.0",
     "@opam/ocamlformat": "0.27.0",
     "@opam/ocaml-lsp-server": "> 1.9.1 < 2.0.0"
   },