diff --git a/packages/node/package.json b/packages/node/package.json
index bfe1acb03a48..6ffe71f06fc3 100644
--- a/packages/node/package.json
+++ b/packages/node/package.json
@@ -95,7 +95,7 @@
     "@opentelemetry/resources": "^1.30.1",
     "@opentelemetry/sdk-trace-base": "^1.30.1",
     "@opentelemetry/semantic-conventions": "^1.30.0",
-    "@prisma/instrumentation": "6.6.0",
+    "@prisma/instrumentation": "6.7.0",
     "@sentry/core": "9.15.0",
     "@sentry/opentelemetry": "9.15.0",
     "import-in-the-middle": "^1.13.0"
diff --git a/packages/node/src/integrations/tracing/index.ts b/packages/node/src/integrations/tracing/index.ts
index e07a247d7d34..99a85b3514f8 100644
--- a/packages/node/src/integrations/tracing/index.ts
+++ b/packages/node/src/integrations/tracing/index.ts
@@ -15,6 +15,7 @@ import { instrumentMongoose, mongooseIntegration } from './mongoose';
 import { instrumentMysql, mysqlIntegration } from './mysql';
 import { instrumentMysql2, mysql2Integration } from './mysql2';
 import { instrumentPostgres, postgresIntegration } from './postgres';
+import { prismaIntegration } from './prisma';
 import { instrumentRedis, redisIntegration } from './redis';
 import { instrumentTedious, tediousIntegration } from './tedious';
 import { instrumentVercelAi, vercelAIIntegration } from './vercelai';
@@ -33,10 +34,7 @@ export function getAutoPerformanceIntegrations(): Integration[] {
     mysql2Integration(),
     redisIntegration(),
     postgresIntegration(),
-    // For now, we do not include prisma by default because it has ESM issues
-    // See https://github.com/prisma/prisma/issues/23410
-    // TODO v8: Figure out a better solution for this, maybe only disable in ESM mode?
-    // prismaIntegration(),
+    prismaIntegration(),
     hapiIntegration(),
     koaIntegration(),
     connectIntegration(),
diff --git a/packages/node/src/integrations/tracing/prisma.ts b/packages/node/src/integrations/tracing/prisma.ts
index 58c0a8019cd8..c674e0bfdfbe 100644
--- a/packages/node/src/integrations/tracing/prisma.ts
+++ b/packages/node/src/integrations/tracing/prisma.ts
@@ -1,6 +1,5 @@
 import type { Instrumentation } from '@opentelemetry/instrumentation';
-// When importing CJS modules into an ESM module, we cannot import the named exports directly.
-import * as prismaInstrumentation from '@prisma/instrumentation';
+import { PrismaInstrumentation } from '@prisma/instrumentation';
 import { consoleSandbox, defineIntegration, SEMANTIC_ATTRIBUTE_SENTRY_ORIGIN, spanToJSON } from '@sentry/core';
 import { generateInstrumentOnce } from '../../otel/instrument';
 import type { PrismaV5TracingHelper } from './prisma/vendor/v5-tracing-helper';
@@ -8,11 +7,6 @@ import type { PrismaV6TracingHelper } from './prisma/vendor/v6-tracing-helper';
 
 const INTEGRATION_NAME = 'Prisma';
 
-const EsmInteropPrismaInstrumentation: typeof prismaInstrumentation.PrismaInstrumentation =
-  // @ts-expect-error We need to do the following for interop reasons
-  // eslint-disable-next-line @typescript-eslint/no-unsafe-member-access
-  prismaInstrumentation.default?.PrismaInstrumentation || prismaInstrumentation.PrismaInstrumentation;
-
 type CompatibilityLayerTraceHelper = PrismaV5TracingHelper & PrismaV6TracingHelper;
 
 function isPrismaV6TracingHelper(helper: unknown): helper is PrismaV6TracingHelper {
@@ -31,7 +25,7 @@ function getPrismaTracingHelper(): unknown | undefined {
   return prismaTracingHelper;
 }
 
-class SentryPrismaInteropInstrumentation extends EsmInteropPrismaInstrumentation {
+class SentryPrismaInteropInstrumentation extends PrismaInstrumentation {
   public constructor() {
     super();
   }
diff --git a/yarn.lock b/yarn.lock
index 334e255ebb3b..938d89058a83 100644
--- a/yarn.lock
+++ b/yarn.lock
@@ -5860,10 +5860,10 @@
   resolved "https://registry.yarnpkg.com/@polka/url/-/url-1.0.0-next.28.tgz#d45e01c4a56f143ee69c54dd6b12eade9e270a73"
   integrity sha512-8LduaNlMZGwdZ6qWrKlfa+2M4gahzFkprZiAt2TF8uS0qQgBizKXpXURqvTJ4WtmupWxaLqjRb2UCTe72mu+Aw==
 
-"@prisma/instrumentation@6.6.0":
-  version "6.6.0"
-  resolved "https://registry.yarnpkg.com/@prisma/instrumentation/-/instrumentation-6.6.0.tgz#5b73164c722bcfcd29c43cb883b4735143b65eb2"
-  integrity sha512-M/a6njz3hbf2oucwdbjNKrSMLuyMCwgDrmTtkF1pm4Nm7CU45J/Hd6lauF2CDACTUYzu3ymcV7P0ZAhIoj6WRw==
+"@prisma/instrumentation@6.7.0":
+  version "6.7.0"
+  resolved "https://registry.yarnpkg.com/@prisma/instrumentation/-/instrumentation-6.7.0.tgz#5fd97be1f89e9d9268148424a812deaea491f80a"
+  integrity sha512-3NuxWlbzYNevgPZbV0ktA2z6r0bfh0g22ONTxcK09a6+6MdIPjHsYx1Hnyu4yOq+j7LmupO5J69hhuOnuvj8oQ==
   dependencies:
     "@opentelemetry/instrumentation" "^0.52.0 || ^0.53.0 || ^0.54.0 || ^0.55.0 || ^0.56.0 || ^0.57.0"