diff --git a/lib/Doctrine/Common/DataFixtures/Purger/ORMPurger.php b/lib/Doctrine/Common/DataFixtures/Purger/ORMPurger.php
index f6346a92..c12f434f 100644
--- a/lib/Doctrine/Common/DataFixtures/Purger/ORMPurger.php
+++ b/lib/Doctrine/Common/DataFixtures/Purger/ORMPurger.php
@@ -5,7 +5,10 @@
 namespace Doctrine\Common\DataFixtures\Purger;
 
 use Doctrine\Common\DataFixtures\Sorter\TopologicalSorter;
+use Doctrine\DBAL\Connection;
+use Doctrine\DBAL\Platforms\AbstractMySQLPlatform;
 use Doctrine\DBAL\Platforms\AbstractPlatform;
+use Doctrine\DBAL\Platforms\MySQLPlatform;
 use Doctrine\DBAL\Schema\Identifier;
 use Doctrine\ORM\EntityManagerInterface;
 use Doctrine\ORM\Mapping\ClassMetadata;
@@ -13,6 +16,7 @@
 use function array_reverse;
 use function array_search;
 use function assert;
+use function class_exists;
 use function count;
 use function is_callable;
 use function method_exists;
@@ -141,6 +145,8 @@ public function purge()
             'getSchemaAssetsFilter'
         ) ? $connection->getConfiguration()->getSchemaAssetsFilter() : null;
 
+        $this->disableForeignKeyChecksForMySQL($connection);
+
         foreach ($orderedTables as $tbl) {
             // If we have a filter expression, check it and skip if necessary
             if (! $emptyFilterExpression && ! preg_match($filterExpr, $tbl)) {
@@ -163,6 +169,8 @@ public function purge()
                 $connection->executeStatement($platform->getTruncateTableSQL($tbl, true));
             }
         }
+
+        $this->enableForeignKeyChecksForMySQL($connection);
     }
 
     /**
@@ -280,4 +288,38 @@ private function getDeleteFromTableSQL(string $tableName, AbstractPlatform $plat
 
         return 'DELETE FROM ' . $tableIdentifier->getQuotedName($platform);
     }
+
+    private function disableForeignKeyChecksForMySQL(Connection $connection): void
+    {
+        if ($this->purgeMode !== self::PURGE_MODE_TRUNCATE || ! $this->isMySQL($connection)) {
+            return;
+        }
+
+        // see MySQL TRUNCATE TABLE Statement: fails for an InnoDB or NDB table
+        // if there are any FOREIGN KEY constraints from other tables that
+        // reference the table.
+        $connection->executeStatement('SET @DOCTRINE_OLD_FOREIGN_KEY_CHECKS = @@FOREIGN_KEY_CHECKS');
+        $connection->executeStatement('SET FOREIGN_KEY_CHECKS = 0');
+    }
+
+    private function enableForeignKeyChecksForMySQL(Connection $connection): void
+    {
+        if ($this->purgeMode !== self::PURGE_MODE_TRUNCATE || ! $this->isMySQL($connection)) {
+            return;
+        }
+
+        $connection->executeStatement('SET FOREIGN_KEY_CHECKS = @DOCTRINE_OLD_FOREIGN_KEY_CHECKS');
+    }
+
+    private function isMySQL(Connection $connection): bool
+    {
+        $platform = $connection->getDatabasePlatform();
+
+        if (! class_exists(AbstractMySQLPlatform::class)) {
+            // before DBAL 3.3
+            return $platform instanceof MySQLPlatform;
+        }
+
+        return $platform instanceof AbstractMySQLPlatform;
+    }
 }
diff --git a/tests/Doctrine/Tests/Common/DataFixtures/Purger/ORMPurgerForeignKeyCheckTest.php b/tests/Doctrine/Tests/Common/DataFixtures/Purger/ORMPurgerForeignKeyCheckTest.php
new file mode 100644
index 00000000..486356a0
--- /dev/null
+++ b/tests/Doctrine/Tests/Common/DataFixtures/Purger/ORMPurgerForeignKeyCheckTest.php
@@ -0,0 +1,104 @@
+<?php
+
+declare(strict_types=1);
+
+namespace Doctrine\Tests\Common\DataFixtures;
+
+use Doctrine\Common\DataFixtures\Purger\ORMPurger;
+use Doctrine\Common\EventManager;
+use Doctrine\DBAL\Configuration;
+use Doctrine\DBAL\Connection;
+use Doctrine\DBAL\Driver\Middleware\AbstractDriverMiddleware;
+use Doctrine\DBAL\Platforms\AbstractPlatform;
+use Doctrine\DBAL\Platforms\MySQLPlatform;
+use Doctrine\DBAL\Platforms\SqlitePlatform;
+use Doctrine\ORM\EntityManager;
+use Doctrine\ORM\Mapping\ClassMetadata;
+use Doctrine\ORM\ORMSetup;
+use Doctrine\Persistence\Mapping\Driver\MappingDriver;
+use Doctrine\Tests\Common\DataFixtures\TestEntity\Link;
+use PHPUnit\Framework\MockObject\MockObject;
+
+class ORMPurgerForeignKeyCheckTest extends BaseTest
+{
+    public const TEST_CLASS_NAME = Link::class;
+    public const TEST_TABLE_NAME = 'link';
+
+    /** @return MappingDriver&MockObject */
+    protected function getMockMetadataDriver(): MappingDriver
+    {
+        $metadataDriver = $this->createMock(MappingDriver::class);
+        $metadataDriver->method('getAllClassNames')->willReturn([self::TEST_CLASS_NAME]);
+        $metadataDriver->method('loadMetadataForClass')
+            ->willReturnCallback(static function (string $className, ClassMetadata $metadata): void {
+                if ($className !== self::TEST_CLASS_NAME) {
+                    return;
+                }
+
+                $metadata->setPrimaryTable(['name' => self::TEST_TABLE_NAME]);
+                $metadata->setIdentifier(['id']);
+            });
+        $metadataDriver->method('isTransient')->willReturn(false);
+
+        return $metadataDriver;
+    }
+
+    /** @return Connection&MockObject */
+    protected function getMockConnectionForPlatform(AbstractPlatform $platform): Connection
+    {
+        $driver = $this->createMock(AbstractDriverMiddleware::class);
+        $driver->method('getDatabasePlatform')->willReturn($platform);
+
+        $connection = $this->createMock(Connection::class);
+        $connection->method('getDriver')->willReturn($driver);
+        $connection->method('getConfiguration')->willReturn(new Configuration());
+        $connection->method('getEventManager')->willReturn(new EventManager());
+        $connection->method('getDatabasePlatform')->willReturn($platform);
+
+        return $connection;
+    }
+
+    /** @dataProvider purgeForDifferentPlatformsProvider */
+    public function testPurgeForDifferentPlatforms(AbstractPlatform $platform, int $purgeMode, bool $hasForeignKeyCheckString): void
+    {
+        $metadataDriver = $this->getMockMetadataDriver();
+        $connection     = $this->getMockConnectionForPlatform($platform);
+
+        $config = ORMSetup::createConfiguration(true);
+        $config->setMetadataDriverImpl($metadataDriver);
+
+        $em     = EntityManager::create($connection, $config);
+        $purger = new ORMPurger($em);
+        $purger->setPurgeMode($purgeMode);
+
+        if ($hasForeignKeyCheckString) {
+            $connection
+                ->expects($this->exactly(4))
+                ->method('executeStatement')
+                ->withConsecutive(
+                    ['SET @DOCTRINE_OLD_FOREIGN_KEY_CHECKS = @@FOREIGN_KEY_CHECKS'],
+                    ['SET FOREIGN_KEY_CHECKS = 0'],
+                    [$this->stringContains(self::TEST_TABLE_NAME)],
+                    ['SET FOREIGN_KEY_CHECKS = @DOCTRINE_OLD_FOREIGN_KEY_CHECKS']
+                );
+        } else {
+            $connection
+                ->expects($this->exactly(1))
+                ->method('executeStatement')
+                ->withConsecutive([$this->stringContains(self::TEST_TABLE_NAME)]);
+        }
+
+        $purger->purge();
+    }
+
+    /** @return list<array{AbstractPlatform, ORMPurger::PURGE_MODE_*, bool}> */
+    public function purgeForDifferentPlatformsProvider(): array
+    {
+        return [
+            [new MySQLPlatform(), ORMPurger::PURGE_MODE_TRUNCATE, true],
+            [new MySQLPlatform(), ORMPurger::PURGE_MODE_DELETE, false],
+            [new SqlitePlatform(), ORMPurger::PURGE_MODE_TRUNCATE, false],
+            [new SqlitePlatform(), ORMPurger::PURGE_MODE_DELETE, false],
+        ];
+    }
+}