diff --git a/src/workerd/api/http.c++ b/src/workerd/api/http.c++
index ff4dc18b223..8c513e0334e 100644
--- a/src/workerd/api/http.c++
+++ b/src/workerd/api/http.c++
@@ -673,7 +673,31 @@ void Request::shallowCopyHeadersTo(kj::HttpHeaders& out) {
 }
 
 kj::Maybe<kj::String> Request::serializeCfBlobJson(jsg::Lock& js) {
-  if (cacheMode == CacheMode::NONE) {
+  // We need to clone the cf object if we're going to modify it. We modify it when:
+  // 1. cacheMode != NONE (existing behavior: map cache option to cacheTtl/cacheLevel/etc.)
+  // 2. cacheControl is not explicitly set and we need to synthesize it from cacheTtl or cacheMode
+  //
+  // For backward compatibility during migration, we dual-write: keep cacheTtl as-is but also
+  // synthesize cacheControl so downstream services can start consuming the unified field.
+  // Once downstream fully migrates to cacheControl, cacheTtl can be removed.
+
+  bool hasCacheMode = (cacheMode != CacheMode::NONE);
+  bool needsSynthesizedCacheControl = false;
+
+  // TODO(cleanup): Remove the workerdExperimental gate once validated in production.
+  bool experimentalCacheControl = FeatureFlags::get(js).getWorkerdExperimental();
+
+  if (!hasCacheMode && experimentalCacheControl) {
+    // Check if cf has cacheTtl but no cacheControl — we'll need to synthesize cacheControl.
+    KJ_IF_SOME(cfObj, cf.get(js)) {
+      if (!cfObj.has(js, "cacheControl") && cfObj.has(js, "cacheTtl")) {
+        auto ttlVal = cfObj.get(js, "cacheTtl");
+        needsSynthesizedCacheControl = !ttlVal.isUndefined();
+      }
+    }
+  }
+
+  if (!hasCacheMode && !needsSynthesizedCacheControl) {
     return cf.serialize(js);
   }
 
@@ -687,25 +711,57 @@ kj::Maybe<kj::String> Request::serializeCfBlobJson(jsg::Lock& js) {
   auto obj = KJ_ASSERT_NONNULL(clone.get(js));
 
   constexpr int NOCACHE_TTL = -1;
-  switch (cacheMode) {
-    case CacheMode::NOSTORE:
-      if (obj.has(js, "cacheTtl")) {
-        jsg::JsValue oldTtl = obj.get(js, "cacheTtl");
-        JSG_REQUIRE(oldTtl.strictEquals(js.num(NOCACHE_TTL)), TypeError,
-            kj::str("CacheTtl: ", oldTtl, ", is not compatible with cache: ",
-                getCacheModeName(cacheMode).orDefault("none"_kj), " header."));
-      } else {
-        obj.set(js, "cacheTtl", js.num(NOCACHE_TTL));
+  if (hasCacheMode) {
+    switch (cacheMode) {
+      case CacheMode::NOSTORE:
+        if (obj.has(js, "cacheTtl")) {
+          jsg::JsValue oldTtl = obj.get(js, "cacheTtl");
+          JSG_REQUIRE(oldTtl.strictEquals(js.num(NOCACHE_TTL)), TypeError,
+              kj::str("CacheTtl: ", oldTtl, ", is not compatible with cache: ",
+                  getCacheModeName(cacheMode).orDefault("none"_kj), " header."));
+        } else {
+          obj.set(js, "cacheTtl", js.num(NOCACHE_TTL));
+        }
+        KJ_FALLTHROUGH;
+      case CacheMode::RELOAD:
+        obj.set(js, "cacheLevel", js.str("bypass"_kjc));
+        break;
+      case CacheMode::NOCACHE:
+        obj.set(js, "cacheForceRevalidate", js.boolean(true));
+        break;
+      case CacheMode::NONE:
+        KJ_UNREACHABLE;
+    }
+  }
+
+  // Synthesize cacheControl from cacheTtl or cacheMode when cacheControl is not explicitly set.
+  // This dual-writes both fields so downstream can migrate to cacheControl incrementally.
+  // TODO(cleanup): Remove the workerdExperimental gate once validated in production.
+  if (experimentalCacheControl && !obj.has(js, "cacheControl")) {
+    if (hasCacheMode) {
+      // Synthesize from the cache request option.
+      switch (cacheMode) {
+        case CacheMode::NOSTORE:
+          obj.set(js, "cacheControl", js.str("no-store"_kjc));
+          break;
+        case CacheMode::NOCACHE:
+          obj.set(js, "cacheControl", js.str("no-cache"_kjc));
+          break;
+        case CacheMode::RELOAD:
+          break;
+        case CacheMode::NONE:
+          KJ_UNREACHABLE;
       }
-      KJ_FALLTHROUGH;
-    case CacheMode::RELOAD:
-      obj.set(js, "cacheLevel", js.str("bypass"_kjc));
-      break;
-    case CacheMode::NOCACHE:
-      obj.set(js, "cacheForceRevalidate", js.boolean(true));
-      break;
-    case CacheMode::NONE:
-      KJ_UNREACHABLE;
+    } else if (obj.has(js, "cacheTtl")) {
+      // Synthesize from cacheTtl value: positive/zero → max-age=N, -1 → no-store.
+      jsg::JsValue ttlVal = obj.get(js, "cacheTtl");
+      if (ttlVal.strictEquals(js.num(NOCACHE_TTL))) {
+        obj.set(js, "cacheControl", js.str("no-store"_kjc));
+      } else KJ_IF_SOME(ttlInt, ttlVal.tryCast<jsg::JsInt32>()) {
+        auto ttl = KJ_ASSERT_NONNULL(ttlInt.value(js));
+        obj.set(js, "cacheControl", js.str(kj::str("max-age=", ttl)));
+      }
+    }
   }
 
   return clone.serialize(js);
@@ -728,6 +784,36 @@ void RequestInitializerDict::validate(jsg::Lock& js) {
         !invalidNoCache && !invalidReload, TypeError, kj::str("Unsupported cache mode: ", c));
   }
 
+  // Validate mutual exclusion of cf.cacheControl with cf.cacheTtl and the cache request option.
+  // cacheControl provides explicit Cache-Control header override and cannot be combined with
+  // cacheTtl (which sets a simplified TTL) or the cache option (which maps to cacheTtl internally).
+  // cacheTtlByStatus is allowed alongside cacheControl since they serve different purposes.
+  // TODO(cleanup): Remove the workerdExperimental gate once validated in production.
+  if (FeatureFlags::get(js).getWorkerdExperimental()) {
+    KJ_IF_SOME(cfRef, cf) {
+      auto cfObj = jsg::JsObject(cfRef.getHandle(js));
+      if (cfObj.has(js, "cacheControl")) {
+        auto cacheControlVal = cfObj.get(js, "cacheControl");
+        if (!cacheControlVal.isUndefined()) {
+          // cacheControl + cacheTtl → throw
+          if (cfObj.has(js, "cacheTtl")) {
+            auto cacheTtlVal = cfObj.get(js, "cacheTtl");
+            JSG_REQUIRE(cacheTtlVal.isUndefined(), TypeError,
+                "The 'cacheControl' and 'cacheTtl' options on cf are mutually exclusive. "
+                "Use 'cacheControl' for explicit Cache-Control header directives, "
+                "or 'cacheTtl' for a simplified TTL, but not both.");
+          }
+          // cacheControl + cache option (no-store/no-cache) → throw
+          // The cache request option maps to cacheTtl internally, so they conflict.
+          JSG_REQUIRE(cache == kj::none, TypeError,
+              "The 'cacheControl' option on cf cannot be used together with the 'cache' "
+              "request option. The 'cache' option ('no-store'/'no-cache') maps to cache TTL "
+              "behavior internally, which conflicts with explicit Cache-Control directives.");
+        }
+      }
+    }
+  }
+
   KJ_IF_SOME(e, encodeResponseBody) {
     JSG_REQUIRE(e == "manual"_kj || e == "automatic"_kj, TypeError,
         kj::str("encodeResponseBody: unexpected value: ", e));
diff --git a/src/workerd/api/tests/BUILD.bazel b/src/workerd/api/tests/BUILD.bazel
index 55dad299471..a6c153b48a3 100644
--- a/src/workerd/api/tests/BUILD.bazel
+++ b/src/workerd/api/tests/BUILD.bazel
@@ -84,6 +84,12 @@ wd_test(
     data = ["http-test.js"],
 )
 
+wd_test(
+    src = "cf-cache-control-test.wd-test",
+    args = ["--experimental"],
+    data = ["cf-cache-control-test.js"],
+)
+
 wd_test(
     src = "ctx-props-test.wd-test",
     args = ["--experimental"],
diff --git a/src/workerd/api/tests/cf-cache-control-test.js b/src/workerd/api/tests/cf-cache-control-test.js
new file mode 100644
index 00000000000..7d68c3c9081
--- /dev/null
+++ b/src/workerd/api/tests/cf-cache-control-test.js
@@ -0,0 +1,184 @@
+// Copyright (c) 2025 Cloudflare, Inc.
+// Licensed under the Apache 2.0 license found in the LICENSE file or at:
+//     https://opensource.org/licenses/Apache-2.0
+
+// Tests for cf.cacheControl mutual exclusion, synthesis, and additional cache settings.
+// These require the workerd_experimental compat flag.
+
+import assert from 'node:assert';
+
+// Tests for cf.cacheControl mutual exclusion and synthesis.
+// These tests run regardless of cache option flag since cacheControl is always available.
+export const cacheControlMutualExclusion = {
+  async test(ctrl, env, ctx) {
+    // cacheControl + cacheTtl → TypeError at construction time
+    assert.throws(
+      () =>
+        new Request('https://example.org', {
+          cf: { cacheControl: 'max-age=300', cacheTtl: 300 },
+        }),
+      {
+        name: 'TypeError',
+        message: /cacheControl.*cacheTtl.*mutually exclusive/,
+      }
+    );
+
+    // cacheControl alone should succeed
+    {
+      const req = new Request('https://example.org', {
+        cf: { cacheControl: 'public, max-age=3600' },
+      });
+      assert.ok(req.cf);
+    }
+
+    // cacheTtl alone should succeed
+    {
+      const req = new Request('https://example.org', {
+        cf: { cacheTtl: 300 },
+      });
+      assert.ok(req.cf);
+    }
+
+    // cacheControl + cacheTtlByStatus should succeed (not mutually exclusive)
+    {
+      const req = new Request('https://example.org', {
+        cf: {
+          cacheControl: 'public, max-age=3600',
+          cacheTtlByStatus: { '200-299': 86400 },
+        },
+      });
+      assert.ok(req.cf);
+    }
+
+    // cacheControl with undefined cacheTtl should succeed (only non-undefined triggers conflict)
+    {
+      const req = new Request('https://example.org', {
+        cf: { cacheControl: 'max-age=300', cacheTtl: undefined },
+      });
+      assert.ok(req.cf);
+    }
+  },
+};
+
+export const cacheControlWithCacheOption = {
+  async test(ctrl, env, ctx) {
+    if (!env.CACHE_ENABLED) return;
+
+    // cache option + cf.cacheControl → TypeError at construction time
+    assert.throws(
+      () =>
+        new Request('https://example.org', {
+          cache: 'no-store',
+          cf: { cacheControl: 'no-cache' },
+        }),
+      {
+        name: 'TypeError',
+        message: /cacheControl.*cannot be used together with the.*cache/,
+      }
+    );
+
+    // cache: 'no-cache' + cf.cacheControl → also TypeError
+    // (need cache_no_cache flag for this, skip if not available)
+  },
+};
+
+export const cacheControlSynthesis = {
+  async test(ctrl, env, ctx) {
+    // When cacheTtl is set without cacheControl, cacheControl should be synthesized
+    // in the serialized cf blob. We verify by checking the cf property roundtrips correctly.
+
+    // cacheTtl: 300 → cacheControl should be synthesized as "max-age=300"
+    {
+      const req = new Request('https://example.org', {
+        cf: { cacheTtl: 300 },
+      });
+      // The cf object at construction time won't have cacheControl yet —
+      // synthesis happens at serialization (fetch) time in serializeCfBlobJson.
+      // We can verify the request constructs fine.
+      assert.ok(req.cf);
+      assert.strictEqual(req.cf.cacheTtl, 300);
+    }
+
+    // cacheTtl: -1 → cacheControl should be synthesized as "no-store"
+    {
+      const req = new Request('https://example.org', {
+        cf: { cacheTtl: -1 },
+      });
+      assert.ok(req.cf);
+      assert.strictEqual(req.cf.cacheTtl, -1);
+    }
+
+    // cacheTtl: 0 → cacheControl should be synthesized as "max-age=0"
+    {
+      const req = new Request('https://example.org', {
+        cf: { cacheTtl: 0 },
+      });
+      assert.ok(req.cf);
+      assert.strictEqual(req.cf.cacheTtl, 0);
+    }
+
+    // Explicit cacheControl should NOT be overwritten
+    {
+      const req = new Request('https://example.org', {
+        cf: { cacheControl: 'public, s-maxage=86400' },
+      });
+      assert.ok(req.cf);
+      assert.strictEqual(req.cf.cacheControl, 'public, s-maxage=86400');
+    }
+  },
+};
+
+export const additionalCacheSettings = {
+  async test(ctrl, env, ctx) {
+    // All additional cache settings should be accepted on the cf object
+    {
+      const req = new Request('https://example.org', {
+        cf: {
+          cacheReserveEligible: true,
+          respectStrongEtag: true,
+          stripEtags: false,
+          stripLastModified: false,
+          cacheDeceptionArmor: true,
+          cacheReserveMinimumFileSize: 1024,
+        },
+      });
+      assert.ok(req.cf);
+      assert.strictEqual(req.cf.cacheReserveEligible, true);
+      assert.strictEqual(req.cf.respectStrongEtag, true);
+      assert.strictEqual(req.cf.stripEtags, false);
+      assert.strictEqual(req.cf.stripLastModified, false);
+      assert.strictEqual(req.cf.cacheDeceptionArmor, true);
+      assert.strictEqual(req.cf.cacheReserveMinimumFileSize, 1024);
+    }
+
+    // Additional cache settings should work alongside cacheControl
+    {
+      const req = new Request('https://example.org', {
+        cf: {
+          cacheControl: 'public, max-age=3600',
+          cacheReserveEligible: true,
+          stripEtags: true,
+        },
+      });
+      assert.ok(req.cf);
+      assert.strictEqual(req.cf.cacheControl, 'public, max-age=3600');
+      assert.strictEqual(req.cf.cacheReserveEligible, true);
+      assert.strictEqual(req.cf.stripEtags, true);
+    }
+
+    // Additional cache settings should work alongside cacheTtl
+    {
+      const req = new Request('https://example.org', {
+        cf: {
+          cacheTtl: 300,
+          respectStrongEtag: true,
+          cacheDeceptionArmor: true,
+        },
+      });
+      assert.ok(req.cf);
+      assert.strictEqual(req.cf.cacheTtl, 300);
+      assert.strictEqual(req.cf.respectStrongEtag, true);
+      assert.strictEqual(req.cf.cacheDeceptionArmor, true);
+    }
+  },
+};
diff --git a/src/workerd/api/tests/cf-cache-control-test.wd-test b/src/workerd/api/tests/cf-cache-control-test.wd-test
new file mode 100644
index 00000000000..55c3cce9ef4
--- /dev/null
+++ b/src/workerd/api/tests/cf-cache-control-test.wd-test
@@ -0,0 +1,28 @@
+using Workerd = import "/workerd/workerd.capnp";
+
+const unitTests :Workerd.Config = (
+  services = [
+    ( name = "cf-cache-control-test",
+      worker = (
+        modules = [
+          ( name = "worker", esModule = embed "cf-cache-control-test.js" )
+        ],
+        bindings = [
+          ( name = "CACHE_ENABLED", json = "false" ),
+        ],
+        compatibilityFlags = ["nodejs_compat", "cache_option_disabled", "experimental"],
+      )
+    ),
+    ( name = "cf-cache-control-test-cache-enabled",
+      worker = (
+        modules = [
+          ( name = "worker-cache-enabled", esModule = embed "cf-cache-control-test.js" )
+        ],
+        bindings = [
+          ( name = "CACHE_ENABLED", json = "true" ),
+        ],
+        compatibilityFlags = ["nodejs_compat", "cache_option_enabled", "experimental"],
+      )
+    ),
+  ],
+);
diff --git a/types/defines/cf.d.ts b/types/defines/cf.d.ts
index 6731b5ba1f5..d7784c0bcb1 100644
--- a/types/defines/cf.d.ts
+++ b/types/defines/cf.d.ts
@@ -119,6 +119,41 @@ interface RequestInitCfProperties extends Record<string, unknown> {
    * (e.g. { '200-299': 86400, '404': 1, '500-599': 0 })
    */
   cacheTtlByStatus?: Record<string, number>;
+  /**
+   * Explicit Cache-Control header value to set on the response stored in cache.
+   * This gives full control over cache directives (e.g. 'public, max-age=3600, s-maxage=86400').
+   *
+   * Cannot be used together with `cacheTtl` or the `cache` request option (`no-store`/`no-cache`),
+   * as these are mutually exclusive cache control mechanisms. Setting both will throw a TypeError.
+   *
+   * Can be used together with `cacheTtlByStatus`.
+   */
+  cacheControl?: string;
+  /**
+   * Whether the response should be eligible for Cache Reserve storage.
+   */
+  cacheReserveEligible?: boolean;
+  /**
+   * Whether to respect strong ETags (as opposed to weak ETags) from the origin.
+   */
+  respectStrongEtag?: boolean;
+  /**
+   * Whether to strip ETag headers from the origin response before caching.
+   */
+  stripEtags?: boolean;
+  /**
+   * Whether to strip Last-Modified headers from the origin response before caching.
+   */
+  stripLastModified?: boolean;
+  /**
+   * Whether to enable Cache Deception Armor, which protects against web cache
+   * deception attacks by verifying the Content-Type matches the URL extension.
+   */
+  cacheDeceptionArmor?: boolean;
+  /**
+   * Minimum file size in bytes for a response to be eligible for Cache Reserve storage.
+   */
+  cacheReserveMinimumFileSize?: number;
   scrapeShield?: boolean;
   apps?: boolean;
   image?: RequestInitCfPropertiesImage;