diff --git a/vyper/venom/passes/remove_unused_variables.py b/vyper/venom/passes/remove_unused_variables.py
index 20f0a55333..3ce5bdf2d3 100644
--- a/vyper/venom/passes/remove_unused_variables.py
+++ b/vyper/venom/passes/remove_unused_variables.py
@@ -26,6 +26,7 @@ def run_pass(self):
             self._process_instruction(inst)
 
         self.analyses_cache.invalidate_analysis(LivenessAnalysis)
+        self.analyses_cache.invalidate_analysis(DFGAnalysis)
 
     def _process_instruction(self, inst):
         if inst.output is None: