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We have an ongoing project to release PTMs and single aminoacid variants coordinate at genome scale. The idea is that the users gave a region of the genome and we can trace all the ptms and variants in that region. Similar to the VCF when every single variant is traced, rather than tracing peptides.
I was wondering if is possible to output in the tool not only the peptide coordinates but also the PTMs coordinates.
The text was updated successfully, but these errors were encountered:
It is possible to calculate the PTM coordinates and generate BED/GTF output format for those.
VCF format is a bit trickier but I think we could get a workaround going by declaring the PTMs insertions instead of substitutions. In cases where three peptides have 2 PTM sites: (i) one peptide with site 1, (ii) one peptide with site 2, and (iii) one peptide with sites 1 and 2 the resulting output then would be just the two sites individually? Information about cooccurrence would get lost.
@cschlaffner :
We have an ongoing project to release PTMs and single aminoacid variants coordinate at genome scale. The idea is that the users gave a region of the genome and we can trace all the ptms and variants in that region. Similar to the VCF when every single variant is traced, rather than tracing peptides.
I was wondering if is possible to output in the tool not only the peptide coordinates but also the PTMs coordinates.
The text was updated successfully, but these errors were encountered: