Dependency issue

[vishnusharma03]

Collecting Mako (from alembic->optuna==2.10.0->-r requirements.txt (line 4))
Using cached Mako-1.2.4-py3-none-any.whl (78 kB)
Using cached Mako-1.2.3-py3-none-any.whl (78 kB)
Using cached Mako-1.2.2-py3-none-any.whl (78 kB)
Using cached Mako-1.2.1-py3-none-any.whl (78 kB)
Using cached Mako-1.2.0-py3-none-any.whl (78 kB)
Using cached Mako-1.1.6-py2.py3-none-any.whl (75 kB)
Using cached Mako-1.1.5-py2.py3-none-any.whl (75 kB)
Using cached Mako-1.1.4-py2.py3-none-any.whl (75 kB)
Using cached Mako-1.1.3-py2.py3-none-any.whl (75 kB)
Using cached Mako-1.1.2-py2.py3-none-any.whl (75 kB)
Using cached Mako-1.1.1.tar.gz (468 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.1.0.tar.gz (463 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.14.tar.gz (462 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.13.tar.gz (460 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.12.tar.gz (460 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.11.tar.gz (461 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.10.tar.gz (460 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.9.tar.gz (459 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.8.tar.gz (468 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.7.tar.gz (564 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.6.tar.gz (575 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.5.tar.gz (574 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.4.tar.gz (574 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.3.tar.gz (565 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.2.tar.gz (564 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.1.tar.gz (473 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-1.0.0.tar.gz (470 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-0.9.1.tar.gz (421 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-0.9.0.tar.gz (420 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-0.8.1.tar.gz (407 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-0.8.0.tar.gz (407 kB)
Preparing metadata (setup.py) ... done
Using cached Mako-0.7.3.tar.gz (401 kB)
Preparing metadata (setup.py) ... error
error: subprocess-exited-with-error

× python setup.py egg_info did not run successfully.
│ exit code: 1
╰─> [1 lines of output]
error in Mako setup command: use_2to3 is invalid.
[end of output]

note: This error originates from a subprocess, and is likely not a problem with pip.
error: metadata-generation-failed

× Encountered error while generating package metadata.
╰─> See above for output.

note: This is an issue with the package mentioned above, not pip.

While installing the requirements, I am getting this error even I am using a virtual environment,
Can anyone explain how to resolve the issue?

[ashutosh1619]

install all the packages with given versions listed in requirements.txt one by one, do not use pip install -r requirements.txt
Also change markupsafe==2.1.