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Adaptive Color Deconvolution (ACD)

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This is an implementation of the color normalization for histological images based on the adaptive color deconvolution as described in our paper:

Yushan Zheng, Zhiguo Jiang, Haopeng Zhang, Fengying Xie, Jun Shi, and Chenghai Xue, Adaptive Color Deconvolution for Histological WSI Normalization, Computer Methods and Programs in Biomedicine, v170 (2019) pp.107-120.

Requirements

  • TensorFlow (1.3 or later)
  • python 3.6
  • numpy 1.14.0
  • opencv-python 3.4.1

Cite

Please cite the following paper if you use this code in your own work:

@article{zhengCMPB2019,
  title   = {Adaptive color deconvolution for histological WSI normalization},
  author  = {Yushan Zheng and Zhiguo Jiang and Haopeng Zhang and Fengying Xie and Jun Shi and Chenghai Xue},
  journal = {Computer Methods and Programs in Biomedicine},
  volume  = {170},
  pages   = {107-120},
  doi     = {doi.org/10.1016/j.cmpb.2019.01.008},
  year    = {2019}
}