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<title></title>
<desc>Creator: FreeHEP Graphics2D Driver Producer: org.freehep.graphicsio.svg.SVGGraphics2D Revision Source:  Date: Thursday, February 15, 2024 at 8:36:28 PM Central European Standard Time</desc>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">persistent, cytotoxicity (pleura </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">or peritoneum) </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">disease </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Release, Cytokine</text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Activation, TGF-beta pathway</text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Inactivation of PPAR&#x03b3;</text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Airway Surface Liquid Height, </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Motile Cilia Number/Length, </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">FOXJ1 Protein, Decreased</text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">proliferation and myofibroblast </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Accumulation, Collagen</text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Increased, activation of T (T) </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">helper (h) type 2 cells </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Secondary genotoxicity</text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Activation, Transforming Growth </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Factor beta pathway </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Interferon-I antiviral response, </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">antagonized by SARS-CoV-2 </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Increase, Cell Proliferation</text>
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<g fill="#b6d7a8" fill-rule="nonzero" fill-opacity="1" stroke="none">
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Growth Factor Beta 1 </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Increased SARS-CoV-2 </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">cells) </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Increased, secretion of </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">lung resident cell membrane </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Increased, Reactive oxygen </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">species </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Increased neurokinin A (NKA) by </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Increase, Mutations</text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Increase, goblet cell number</text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Increased CGRP, neuronal </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">release of CGRP </text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">Deposition of Energy</text>
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<text font-weight="normal" font-size="12" font-family="Helvetica" font-style="normal" fill="#000000" fill-opacity="1" stroke="none" x="0" y="0">and Chronic Cough, </text>
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