diff --git a/cpu/stm32/include/periph/cpu_usbdev.h b/cpu/stm32/include/periph/cpu_usbdev.h
index 8e97b0b440bd..63219683952a 100644
--- a/cpu/stm32/include/periph/cpu_usbdev.h
+++ b/cpu/stm32/include/periph/cpu_usbdev.h
@@ -10,7 +10,7 @@
 #pragma once
 
 /**
- * @ingroup         cpu_stm32
+ * @ingroup         cpu_stm32_usbdev
  * @{
  *
  * @file
@@ -38,18 +38,30 @@ extern "C" {
  */
 #define USBDEV_CPU_DMA_REQUIREMENTS    __attribute__((aligned(USBDEV_CPU_DMA_ALIGNMENT)))
 
+/**
+ * @name Flags used in @ref stm32_usbdev_fs_config_t
+ * @{
+ */
+/**
+ * @brief Indicates that logic levels are inverted compared to a GPIO connected
+ *        directly via a 1.5 kOhm resistor to the USB D+ signal.
+ */
+#define STM32_USBDEV_FS_CONFIG_FLAG_DISCONN_INVERTED 0x01
+/** @} */
+
 /**
  * @brief stm32 USB device FS configuration
  */
 typedef struct {
     uintptr_t base_addr;            /**< USB peripheral base address */
     uint32_t rcc_mask;              /**< bit in clock enable register */
-    uint8_t irqn;                   /**< IRQ channel */
-    uint8_t apb;                    /**< APB bus */
     gpio_t dm;                      /**< Data- gpio */
     gpio_t dp;                      /**< Data+ gpio */
     gpio_af_t af;                   /**< Alternative function */
     gpio_t disconn;                 /**< GPIO if used for USB disconnect */
+    uint8_t irqn;                   /**< IRQ channel */
+    uint8_t apb;                    /**< APB bus */
+    uint8_t flags;                  /**< Configuration flags */
 } stm32_usbdev_fs_config_t;
 
 #ifdef __cplusplus
diff --git a/cpu/stm32/periph/usbdev_fs.c b/cpu/stm32/periph/usbdev_fs.c
index 5ffd3d837741..88cd6743d49f 100644
--- a/cpu/stm32/periph/usbdev_fs.c
+++ b/cpu/stm32/periph/usbdev_fs.c
@@ -240,7 +240,7 @@ static void _enable_gpio(const stm32_usbdev_fs_config_t *conf)
         /* In case the MCU has no internal D+ pullup, a GPIO is used to
          * connect/disconnect from USB bus */
         gpio_init(conf->disconn, GPIO_OUT);
-        gpio_clear(conf->disconn);
+        gpio_write(conf->disconn, (conf->flags & STM32_USBDEV_FS_CONFIG_FLAG_DISCONN_INVERTED));
     }
 }
 
@@ -283,7 +283,7 @@ static inline void _usb_attach(stm32_usbdev_fs_t *usbdev)
 #else
     /* If configuration uses a GPIO for USB connect/disconnect */
     if (conf->disconn != GPIO_UNDEF) {
-        gpio_set(conf->disconn);
+        gpio_write(conf->disconn, !(conf->flags & STM32_USBDEV_FS_CONFIG_FLAG_DISCONN_INVERTED));
     }
 #endif /* USB_BCDR_DPPU */
 }
@@ -301,7 +301,7 @@ static inline void _usb_detach(stm32_usbdev_fs_t *usbdev)
 #else
     /* If configuration uses a GPIO for USB connect/disconnect */
     if (conf->disconn != GPIO_UNDEF) {
-        gpio_clear(conf->disconn);
+        gpio_write(conf->disconn, (conf->flags & STM32_USBDEV_FS_CONFIG_FLAG_DISCONN_INVERTED));
     }
 #endif
 }